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P07331 (MOS_MSVMH) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase-transforming protein mos

EC=2.7.11.1
Gene names
Name:V-MOS
OrganismMoloney murine sarcoma virus (strain HT-1) (MoMSV)
Taxonomic identifier11810 [NCBI]
Taxonomic lineageVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeGammaretrovirus
Virus hostMus musculus (Mouse) [TaxID: 10090]

Protein attributes

Sequence length374 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 374374Serine/threonine-protein kinase-transforming protein mos
PRO_0000086359

Regions

Domain94 – 370277Protein kinase
Nucleotide binding100 – 1089ATP By similarity

Sites

Active site2291Proton acceptor By similarity
Binding site1211ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P07331 [UniParc].

Last modified April 1, 1988. Version 1.
Checksum: B124C62202DCBB0C

FASTA37441,094
        10         20         30         40         50         60 
MARSTPCSQT SLAVPTHFSL VSHVTVPSEG VMPSPLSLCR YLPRELSPSV DSRSCSIPLV 

        70         80         90        100        110        120 
APRKAGKLFL GTTPPRAPGL PRRLAWFSID WEQVCLMHRL GSGGFGSVYK ATYHGVPVAI 

       130        140        150        160        170        180 
KQVNKCTKDL RASQRSFWAE LNIARLRHDN IVRVVAASTR TPEDSNSLGT IIMEFGGNVT 

       190        200        210        220        230        240 
LHQVIYGATR SPEPLSCREQ LSLGKCLKYS LDVVNGLLFL HSQSILHLDL KPANILISEQ 

       250        260        270        280        290        300 
DVCKISDFGC SQKLQDLRCR QASPHHIGGT YTHQAPEILK GEIATPKADI YSFGITLWQM 

       310        320        330        340        350        360 
TTREVPYSGE PQYVQYAVVA YNLRPSLAGA VFTASLTGKT LQNIIQSCWE ARALQRPGAE 

       370 
LLQRDLKAFR GALG 

« Hide

References

[1]"Nucleotide sequence and biochemical activities of the Moloney murine sarcoma virus strain HT-1 mos gene."
Seth A., Vande Woude G.F.
J. Virol. 56:144-152(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M11909 mRNA. Translation: AAA46496.1.
PIRTVMVHT. A25318.

3D structure databases

ProteinModelPortalP07331.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BRENDA2.7.10.2. 3394.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMOS_MSVMH
AccessionPrimary (citable) accession number: P07331
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: October 16, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families