P07296 (VNCS_PAVBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Non-capsid protein NS-1

Alternative name(s):
Non-structural protein NS1

Gene names

Name:

NS1

Organism

Bovine parvovirus (isolate pAT153/1986) (BPV)

Taxonomic identifier

648243 [NCBI]

Taxonomic lineage

Viruses › ssDNA viruses › Parvoviridae › Parvovirinae › Bocavirus

Virus host

Bos taurus (Bovine) [TaxID: 9913]

Protein attributes

Sequence length	726 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the parvoviruses non-capsid protein family. Contains 1 SF3 helicase domain.

Ontologies

Keywords
Biological process	DNA replication Initiation of viral infection Viral penetration into host cytoplasm Viral penetration via permeabilization of host organellar membrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW viral genome replication Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 726	726	Non-capsid protein NS-1		PRO_0000222471
Regions
	Domain	284 – 439	156	SF3 helicase
	Nucleotide binding	310 – 317	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P07296 [UniParc]. Last modified April 1, 1988. Version 1. Checksum: 42659A611A3AF038	FASTA	726	81,189
	10 20 30 40 50 60 MQPSRGLYSA LHSFKHLLIT IRQRTHAPDT VLSRDELNAW NWLQKIAQRV MRGDMDDIVD 70 80 90 100 110 120 ILKCRKANGT LVAQAINGTE FITRYMLPKN RKVADTVLTR HTTPEQSYDS TWGKTYGFAV 130 140 150 160 170 180 CNGETVSEFT RKDLWKVLYN IYTAHPAENM LNSNPSVWGD LPRVSANRID ADDAEARSRP 190 200 210 220 230 240 IKLSRKQKIM AEVIQRATDG LLLTYNDLVV HLSDLMLMLE GMPGGSKTAE QLLTMIHIKL 250 260 270 280 290 300 CAKYNAYEFM LMKTPATQNM NPGAPHYDCQ GNLVFKLLNL QGYNPWQVGH WLVMMLSKKT 310 320 330 340 350 360 GKRNSTLFYG PASTGKTNLA KAICHAVGLY GCVNHNNKQF PFNDAPNKMI LWWEECIMTT 370 380 390 400 410 420 DYVEAAKCVL GGTHVRVDVK HKDSRELPQI PVLLSSNHDV YTVVGGNATF GVHAAPLKER 430 440 450 460 470 480 ITQMNFMKQL PNTFGEITPG MISNWLSHCA HIHQEHLSLE GFAIKWDVQS VGNSFPLQTL 490 500 510 520 530 540 CPGHSQNWTF SENGVCWHCG GFIQPTPESD TDSDGDPDPD GAVAGDSDTS ANSESTVSFS 550 560 570 580 590 600 SNDSGLGSVT SSAPSVPDRA EEIEEIPSEC LEWMREEVDR LSAHDINSLA HQATGFILDP 610 620 630 640 650 660 IPEEPEEGER DLAREDAEPE ASTSHTPATK RARVEEGEPW DGTQPITEGD WIDFESRQKR 670 680 690 700 710 720 RRLEREEKGG EDEDMEVQES DPSAWGEKLG IVEKPGEEPI VLYCFETLPE SDEEGDSDKE NKTHTV

References

[1]	"Complete nucleotide sequence and genome organization of bovine parvovirus." Chen K.C., Shull B.C., Moses E.A., Lederman M., Stout E.R., Bates R.C. J. Virol. 60:1085-1097(1986) [PubMed: 3783814] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M14363 Genomic DNA. Translation: AAB59845.1.
PIR	UYPVS1. C26104.
RefSeq	NP_041402.1. NC_001540.1.
3D structure databases
ProteinModelPortal	P07296.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1724585.
Family and domain databases
InterPro	IPR014015. Helicase_SF3_DNA-vir. IPR001257. Parvovirus_NS1_helicase. [Graphical view]
Pfam	PF01057. Parvo_NS1. 1 hit. [Graphical view]
PROSITE	PS51206. SF3_HELICASE_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VNCS_PAVBP

Accession

Primary (citable) accession number: P07296

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1988
Last sequence update:	April 1, 1988
Last modified:	September 21, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program