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Protein

Myosin essential light chain, striated adductor muscle

Gene
N/A
Organism
Argopecten irradians (Bay scallop) (Aequipecten irradians)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca2+ dependent binding and Ca2+ dependent Mg-ATPase activity.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, Muscle protein, Myosin

Names & Taxonomyi

Protein namesi
Recommended name:
Myosin essential light chain, striated adductor muscle
Short name:
E-LC
Alternative name(s):
Sulfhydryl light chain
Short name:
SHLC
OrganismiArgopecten irradians (Bay scallop) (Aequipecten irradians)
Taxonomic identifieri31199 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaPectinoidaPectinoideaPectinidaeArgopecten

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001987182 – 157Myosin essential light chain, striated adductor muscleAdd BLAST156

Proteomic databases

PRIDEiP07291.

Structurei

Secondary structure

1157
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 22Combined sources17
Beta strandi25 – 27Combined sources3
Helixi31 – 33Combined sources3
Helixi34 – 40Combined sources7
Helixi47 – 52Combined sources6
Beta strandi57 – 61Combined sources5
Beta strandi63 – 65Combined sources3
Helixi66 – 76Combined sources11
Helixi84 – 92Combined sources9
Beta strandi96 – 103Combined sources8
Helixi104 – 113Combined sources10
Beta strandi114 – 116Combined sources3
Helixi120 – 130Combined sources11
Beta strandi138 – 141Combined sources4
Helixi142 – 151Combined sources10
Turni152 – 155Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B7TX-ray2.50Z2-157[»]
1DFKX-ray4.20Z4-155[»]
1DFLX-ray4.20X/Z4-155[»]
1KK7X-ray3.20Z2-157[»]
1KK8X-ray2.30C2-155[»]
1KQMX-ray3.00C2-157[»]
1KWOX-ray3.80C2-157[»]
1L2OX-ray2.80C2-157[»]
1QVIX-ray2.54Z2-157[»]
1S5GX-ray3.10Z2-157[»]
1SCMX-ray2.80C5-153[»]
1SR6X-ray2.75C2-157[»]
1WDCX-ray2.00C2-157[»]
2W4Telectron microscopy35.00Z5-155[»]
2W4Velectron microscopy35.00Z5-155[»]
2W4Welectron microscopy35.00Z5-155[»]
3JTDX-ray2.57C2-156[»]
3JVTX-ray2.10C2-157[»]
ProteinModelPortaliP07291.
SMRiP07291.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP07291.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 44EF-hand 1PROSITE-ProRule annotationAdd BLAST38
Domaini82 – 117EF-hand 2PROSITE-ProRule annotationAdd BLAST36

Sequence similaritiesi

Contains 2 EF-hand domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

CDDicd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS50222. EF_HAND_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P07291-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKLSQDEID DLKDVFELFD FWDGRDGAVD AFKLGDVCRC LGINPRNEDV
60 70 80 90 100
FAVGGTHKMG EKSLPFEEFL PAYEGLMDCE QGTFADYMEA FKTFDREGQG
110 120 130 140 150
FISGAELRHV LTALGERLSD EDVDEIIKLT DLQEDLEGNV KYEDFVKKVM

AGPYPDK
Length:157
Mass (Da):17,748
Last modified:January 23, 2007 - v2
Checksum:iC34640DDE2A27386
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M17201 mRNA. Translation: AAA27714.1.
PIRiA25183.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M17201 mRNA. Translation: AAA27714.1.
PIRiA25183.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B7TX-ray2.50Z2-157[»]
1DFKX-ray4.20Z4-155[»]
1DFLX-ray4.20X/Z4-155[»]
1KK7X-ray3.20Z2-157[»]
1KK8X-ray2.30C2-155[»]
1KQMX-ray3.00C2-157[»]
1KWOX-ray3.80C2-157[»]
1L2OX-ray2.80C2-157[»]
1QVIX-ray2.54Z2-157[»]
1S5GX-ray3.10Z2-157[»]
1SCMX-ray2.80C5-153[»]
1SR6X-ray2.75C2-157[»]
1WDCX-ray2.00C2-157[»]
2W4Telectron microscopy35.00Z5-155[»]
2W4Velectron microscopy35.00Z5-155[»]
2W4Welectron microscopy35.00Z5-155[»]
3JTDX-ray2.57C2-156[»]
3JVTX-ray2.10C2-157[»]
ProteinModelPortaliP07291.
SMRiP07291.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP07291.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP07291.

Family and domain databases

CDDicd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS50222. EF_HAND_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMLE_ARGIR
AccessioniPrimary (citable) accession number: P07291
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: January 23, 2007
Last modified: November 30, 2016
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.