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Protein

Myosin essential light chain, striated adductor muscle

Gene
N/A
Organism
Argopecten irradians (Bay scallop) (Aequipecten irradians)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca2+ dependent binding and Ca2+ dependent Mg-ATPase activity.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, Muscle protein, Myosin

Names & Taxonomyi

Protein namesi
Recommended name:
Myosin essential light chain, striated adductor muscle
Short name:
E-LC
Alternative name(s):
Sulfhydryl light chain
Short name:
SHLC
OrganismiArgopecten irradians (Bay scallop) (Aequipecten irradians)
Taxonomic identifieri31199 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaPectinoidaPectinoideaPectinidaeArgopecten

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 157156Myosin essential light chain, striated adductor musclePRO_0000198718Add
BLAST

Structurei

Secondary structure

1
157
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 2217Combined sources
Beta strandi25 – 273Combined sources
Helixi31 – 333Combined sources
Helixi34 – 407Combined sources
Helixi47 – 526Combined sources
Beta strandi57 – 615Combined sources
Beta strandi63 – 653Combined sources
Helixi66 – 7611Combined sources
Helixi84 – 929Combined sources
Beta strandi96 – 1038Combined sources
Helixi104 – 11310Combined sources
Beta strandi114 – 1163Combined sources
Helixi120 – 13011Combined sources
Beta strandi138 – 1414Combined sources
Helixi142 – 15110Combined sources
Turni152 – 1554Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1B7TX-ray2.50Z2-157[»]
1DFKX-ray4.20Z4-155[»]
1DFLX-ray4.20X/Z4-155[»]
1KK7X-ray3.20Z2-157[»]
1KK8X-ray2.30C2-155[»]
1KQMX-ray3.00C2-157[»]
1KWOX-ray3.80C2-157[»]
1L2OX-ray2.80C2-157[»]
1QVIX-ray2.54Z2-157[»]
1S5GX-ray3.10Z2-157[»]
1SCMX-ray2.80C5-153[»]
1SR6X-ray2.75C2-157[»]
1WDCX-ray2.00C2-157[»]
2W4Telectron microscopy35.00Z5-155[»]
2W4Velectron microscopy35.00Z5-155[»]
2W4Welectron microscopy35.00Z5-155[»]
3JTDX-ray2.57C2-156[»]
3JVTX-ray2.10C2-157[»]
ProteinModelPortaliP07291.
SMRiP07291. Positions 2-156.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP07291.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 4438EF-hand 1PROSITE-ProRule annotationAdd
BLAST
Domaini82 – 11736EF-hand 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 EF-hand domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS50222. EF_HAND_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P07291-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKLSQDEID DLKDVFELFD FWDGRDGAVD AFKLGDVCRC LGINPRNEDV
60 70 80 90 100
FAVGGTHKMG EKSLPFEEFL PAYEGLMDCE QGTFADYMEA FKTFDREGQG
110 120 130 140 150
FISGAELRHV LTALGERLSD EDVDEIIKLT DLQEDLEGNV KYEDFVKKVM

AGPYPDK
Length:157
Mass (Da):17,748
Last modified:January 23, 2007 - v2
Checksum:iC34640DDE2A27386
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M17201 mRNA. Translation: AAA27714.1.
PIRiA25183.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M17201 mRNA. Translation: AAA27714.1.
PIRiA25183.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1B7TX-ray2.50Z2-157[»]
1DFKX-ray4.20Z4-155[»]
1DFLX-ray4.20X/Z4-155[»]
1KK7X-ray3.20Z2-157[»]
1KK8X-ray2.30C2-155[»]
1KQMX-ray3.00C2-157[»]
1KWOX-ray3.80C2-157[»]
1L2OX-ray2.80C2-157[»]
1QVIX-ray2.54Z2-157[»]
1S5GX-ray3.10Z2-157[»]
1SCMX-ray2.80C5-153[»]
1SR6X-ray2.75C2-157[»]
1WDCX-ray2.00C2-157[»]
2W4Telectron microscopy35.00Z5-155[»]
2W4Velectron microscopy35.00Z5-155[»]
2W4Welectron microscopy35.00Z5-155[»]
3JTDX-ray2.57C2-156[»]
3JVTX-ray2.10C2-157[»]
ProteinModelPortaliP07291.
SMRiP07291. Positions 2-156.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP07291.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS50222. EF_HAND_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMLE_ARGIR
AccessioniPrimary (citable) accession number: P07291
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: January 23, 2007
Last modified: May 11, 2016
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.