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Protein

Somatoliberin

Gene

GHRH

Organism
Ovis aries (Sheep)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone.

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Somatoliberin
Alternative name(s):
Growth hormone-releasing factor
Short name:
GRF
Growth hormone-releasing hormone
Short name:
GHRH
Gene namesi
Name:GHRH
OrganismiOvis aries (Sheep)
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis
Proteomesi
  • UP000002356 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001489221 – 44SomatoliberinAdd BLAST44

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei44Leucine amide1 Publication1

Keywords - PTMi

Amidation

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the glucagon family.Curated

Phylogenomic databases

HOVERGENiHBG017807.

Family and domain databases

InterProiView protein in InterPro
IPR000532. Glucagon_GIP_secretin_VIP.
PfamiView protein in Pfam
PF00123. Hormone_2. 1 hit.
SMARTiView protein in SMART
SM00070. GLUCA. 1 hit.
PROSITEiView protein in PROSITE
PS00260. GLUCAGON. 1 hit.

Sequencei

Sequence statusi: Complete.

P07217-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
YADAIFTNSY RKILGQLSAR KLLQDIMNRQ QGERNQEQGA KVRL
Length:44
Mass (Da):5,123
Last modified:April 1, 1988 - v1
Checksum:i9F907C6769F48030
GO

Sequence databases

UniGeneiOar.14370.
Oar.5775.

Similar proteinsi

Entry informationi

Entry nameiSLIB_SHEEP
AccessioniPrimary (citable) accession number: P07217
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: August 30, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families