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P07173 (CYCR_BLAVI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 111. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Photosynthetic reaction center cytochrome c subunit
Alternative name(s):
Cytochrome c558/c559
Gene names
Name:pufC
Synonyms:cytC
OrganismBlastochloris viridis (Rhodopseudomonas viridis)
Taxonomic identifier1079 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesHyphomicrobiaceaeBlastochloris

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.

Subcellular location

Cell membrane; Lipid-anchor.

Post-translational modification

Binds 4 heme groups per subunit.

After the signal sequence is removed, the N-terminal cysteine is modified to form a diacylglyceride thioether, but the alpha-amino group is free and is not N-palmitoylated.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020
Chain21 – 356336Photosynthetic reaction center cytochrome c subunit
PRO_0000006551

Sites

Metal binding941Iron (heme 1 axial ligand)
Metal binding1111Iron (heme 1 axial ligand)
Metal binding1301Iron (heme 2 axial ligand)
Metal binding1441Iron (heme 4 axial ligand)
Metal binding1561Iron (heme 2 axial ligand)
Metal binding2531Iron (heme 3 axial ligand)
Metal binding2681Iron (heme 3 axial ligand)
Metal binding3291Iron (heme 4 axial ligand)
Binding site1071Heme 1 (covalent)
Binding site1101Heme 1 (covalent)
Binding site1521Heme 2 (covalent)
Binding site1551Heme 2 (covalent)
Binding site2641Heme 3 (covalent)
Binding site2671Heme 3 (covalent)
Binding site3251Heme 4 (covalent)
Binding site3281Heme 4 (covalent)
Site211Not N-palmitoylated

Amino acid modifications

Lipidation211S-diacylglycerol cysteine

Secondary structure

............................................................. 356
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P07173 [UniParc].

Last modified April 1, 1988. Version 1.
Checksum: ECE3D64F1BB0877A

FASTA35639,371
        10         20         30         40         50         60 
MKQLIVNSVA TVALASLVAG CFEPPPATTT QTGFRGLSMG EVLHPATVKA KKERDAQYPP 

        70         80         90        100        110        120 
ALAAVKAEGP PVSQVYKNVK VLGNLTEAEF LRTMTAITEW VSPQEGCTYC HDENNLASEA 

       130        140        150        160        170        180 
KYPYVVARRM LEMTRAINTN WTQHVAQTGV TCYTCHRGTP LPPYVRYLEP TLPLNNRETP 

       190        200        210        220        230        240 
THVERVETRS GYVVRLAKYT AYSALNYDPF TMFLANDKRQ VRVVPQTALP LVGVSRGKER 

       250        260        270        280        290        300 
RPLSDAYATF ALMMSISDSL GTNCTFCHNA QTFESWGKKS TPQRAIAWWG IRMVRDLNMN 

       310        320        330        340        350 
YLAPLNASLP ASRLGRQGEA PQADCRTCHQ GVTKPLFGAS RLKDYPELGP IKAAAK 

« Hide

References

[1]"Amino acid sequence of the cytochrome subunit of the photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis."
Weyer K.A., Lottspeich F., Lang F., Oesterhelt D., Michel H.
EMBO J. 6:2197-2202(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE.
Strain: ATCC 19567 / DSM 133 / F.
[2]"The cytochrome subunit of the photosynthetic reaction center from Rhodopseudomonas viridis is a lipoprotein."
Weyer K.A., Schaefer W., Lottspeich F., Michel H.
Biochemistry 26:2909-2914(1987)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-46, DIACYLGLYCEROL AT CYS-21.
[3]"Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3-A resolution."
Deisenhofer J., Epp O., Miki K., Huber R., Michel H.
Nature 318:618-624(1985)
Cited for: X-RAY CRYSTALLOGRAPHY (3 ANGSTROMS).
[4]"X-ray structure analysis of a membrane protein complex. Electron density map at 3-A resolution and a model of the chromophores of the photosynthetic reaction center from Rhodopseudomonas viridis."
Deisenhofer J., Epp O., Miki K., Huber R., Michel H.
J. Mol. Biol. 180:385-398(1984) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3 ANGSTROMS).
[5]"The coupling of light-induced electron transfer and proton uptake as derived from crystal structures of reaction centres from Rhodopseudomonas viridis modified at the binding site of the secondary quinone, QB."
Lancaster C.R.D., Michel H.
Structure 5:1339-1359(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.45 ANGSTROMS).
Strain: ATCC 19567 / DSM 133 / F.
[6]"Refined crystal structures of reaction centres from Rhodopseudomonas viridis in complexes with the herbicide atrazine and two chiral atrazine derivatives also lead to a new model of the bound carotenoid."
Lancaster C.R.D., Michel H.
J. Mol. Biol. 286:883-898(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS).
Strain: ATCC 19567 / DSM 133 / F.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X05768 Genomic DNA. Translation: CAA29223.1.
M16317 Genomic DNA. Translation: AAA26093.1.
PIRS00139.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1DXRX-ray2.00C21-352[»]
1PRCX-ray2.30C21-356[»]
1R2CX-ray2.86C21-356[»]
1VRNX-ray2.20C21-352[»]
2I5NX-ray1.96C21-356[»]
2JBLX-ray2.40C1-356[»]
2PRCX-ray2.45C21-356[»]
2WJMX-ray1.95C21-356[»]
2WJNX-ray1.86C21-356[»]
2X5UX-ray3.00C21-356[»]
2X5VX-ray3.00C21-356[»]
3D38X-ray3.21C21-356[»]
3G7FX-ray2.50C21-356[»]
3PRCX-ray2.40C21-356[»]
3T6DX-ray1.95C1-356[»]
3T6EX-ray1.92C1-356[»]
4AC5X-ray8.20C21-356[»]
4CASX-ray3.50A1-356[»]
5PRCX-ray2.35C21-356[»]
6PRCX-ray2.30C21-356[»]
7PRCX-ray2.65C21-356[»]
ProteinModelPortalP07173.
SMRP07173. Positions 21-352.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.468.10. 2 hits.
InterProIPR011031. Multihaem_cyt.
IPR023119. Multihaem_cyt_PRC_cyt_su-like.
IPR003158. Photosyn_RC_cyt_c-su.
[Graphical view]
PfamPF02276. CytoC_RC. 1 hit.
[Graphical view]
PIRSFPIRSF000017. RC_cytochrome. 1 hit.
PROSITEPS51008. MULTIHEME_CYTC. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP07173.

Entry information

Entry nameCYCR_BLAVI
AccessionPrimary (citable) accession number: P07173
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: July 9, 2014
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references