P07169 (VIRBB_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein VirB11

Gene names

Name:	virB11
Ordered Locus Names:	Atu6177
ORF Names:	AGR_pTi_14

Encoded on

Plasmid pTiC58

Organism

Agrobacterium tumefaciens (strain C58 / ATCC 33970) [Reference proteome] [HAMAP]

Taxonomic identifier

176299 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium › Agrobacterium tumefaciens complex › Agrobacterium fabrum

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the transfer of T-DNA to plants. Couples energy, by means of ATP hydrolysis, to T-DNA transport.
Subcellular location	Cytoplasm Probable.
Post-translational modification	Autophosphorylated.
Sequence similarities	Belongs to the GSP E family.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cytoplasm
Disease	Crown gall tumor
Ligand	ATP-binding Nucleotide-binding
PTM	Phosphoprotein
Technical term	Complete proteome Plasmid Reference proteome
Gene Ontology (GO)
Biological_process	pathogenesis Inferred from electronic annotation. Source: InterPro protein secretion by the type IV secretion system Inferred from genomic context Ref.1. Source: PAMGO_GAT
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell type IV secretion system complex Inferred from genomic context Ref.1. Source: PAMGO_GAT
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Protein VirB11		PRO_0000207302
Regions
	Nucleotide binding	169 – 176	8	ATP Potential
Experimental info
	Sequence conflict	136	1	D → A in CAA37364. Ref.1
	Sequence conflict	136	1	D → A in AAA91601. Ref.2
	Sequence conflict	136	1	D → A in AAD15210. Ref.6
	Sequence conflict	136	1	D → A in CAA68594. Ref.6

Sequences

	Sequence		Length	Mass (Da)
	P07169 [UniParc]. Last modified March 27, 2002. Version 3. Checksum: 90FFF1BE8D27348F	FASTA	344	38,140
	10 20 30 40 50 60 MEVDPQLRIL LKPILEWLDD PRTEEVAINR PGEAFVRQAG AFLKFPLPVS YDDLEDIAIL 70 80 90 100 110 120 AGALRKQDVG PRNPLCATEL PDGERLQICL PPTVPSGTVS LTIRRPSSRV SSLKEVSSRY 130 140 150 160 170 180 DAPRWNQWKE RKKRHDQHDE AILRYYDNGD LEAFLHACVV GRLTMLLCGP TGSGKTTMSK 190 200 210 220 230 240 TLINAIPPQE RLITIEDTLE LVIPHENHVR LLYSKNGAGL GAVTAEHLLQ ASLRMRPDRI 250 260 270 280 290 300 LLGEIRDDAA WAYLSEVVSG HPGSISTIHG ANPVQGFKKL FSLVKSSAQG ASLEDRTLID 310 320 330 340 MLATAVDVIV PFRAHGDIYE VGEIWLAADA RRRGETIGDL LNQQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The virB operon of Agrobacterium tumefaciens pTiC58 encodes 11 open reading frames." Kuldau G.A., de Vos G., Owen J., McCaffrey G., Zambryski P. Mol. Gen. Genet. 221:256-266(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Molecular characterization of the vir regulon of Agrobacterium tumefaciens: complete nucleotide sequence and gene organization of the 28.63-kbp regulon cloned as a single unit." Rogowsky P.M., Powell B.S., Shirasu K., Lin T.-S., Morel P., Zyprian E.M., Steck T.R., Kado C.I. Plasmid 23:85-106(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis." Shirasu K., Morel P., Kado C.I. Mol. Microbiol. 4:1153-1163(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[4]	"The genome of the natural genetic engineer Agrobacterium tumefaciens C58." Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J. , Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W. Science 294:2317-2323(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58." Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C. , Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S. Science 294:2323-2328(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.
[6]	"Nucleotide sequence of the virG locus of the Agrobacterium tumefaciens plasmid pTiC58." Powell B.S., Powell G.K., Morris R.O., Rogowsky P.M., Kado C.I. Mol. Microbiol. 1:309-316(1987) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 94-344.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X53264 Genomic DNA. Translation: CAA37364.1. J03320 Genomic DNA. Translation: AAA91601.1. AE007871 Genomic DNA. Translation: AAK90939.2. Y00535 Genomic DNA. Translation: CAA68594.1. M36786 Genomic DNA. Translation: AAD15210.1.
PIR	AG3249. BXAG58. S12351.
RefSeq	NP_396498.2. NC_003065.3.
3D structure databases
ProteinModelPortal	P07169.
ModBase	Search...
Protein-protein interaction databases
STRING	176299.Atu6177.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK90939; AAK90939; Atu6177.
GeneID	1137500.
KEGG	atu:Atu6177.
PATRIC	20820554. VBIAgrTum91616_5371.
Phylogenomic databases
eggNOG	COG0630.
HOGENOM	HOG000119934.
KO	K03196.
OMA	TMSKTLI.
ProtClustDB	PRK13851.
Family and domain databases
InterPro	IPR001482. T2SS_protein-E. IPR014155. VirB11. [Graphical view]
Pfam	PF00437. T2SE. 1 hit. [Graphical view]
TIGRFAMs	TIGR02788. VirB11. 1 hit.
PROSITE	PS00662. T2SP_E. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VIRBB_AGRT5

Accession

Primary (citable) accession number: P07169

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1988
Last sequence update:	March 27, 2002
Last modified:	May 1, 2013
This is version 106 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program