P07021 (YFIB_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative lipoprotein YfiB

Gene names

Name:	yfiB
Ordered Locus Names:	b2605, JW2586

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Lipid-anchor Potential.
Sequence similarities	Belongs to the OmpA family. Contains 1 OmpA-like domain.
Sequence caution	The sequence CAA25961.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: InterPro integral to membrane Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 160	142	Putative lipoprotein YfiB		PRO_0000020137
Regions
	Domain	43 – 160	118	OmpA-like
Amino acid modifications
	Lipidation	19	1	N-palmitoyl cysteine Potential
	Lipidation	19	1	S-diacylglycerol cysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	P07021 [UniParc]. Last modified August 1, 1992. Version 2. Checksum: 33FE5FBB174B7889	FASTA	160	17,245
	10 20 30 40 50 60 MIKHLVAPLV FTSLILTGCQ SPQGKFTPEQ VAAMQSYGFT ESAGDWSLGL SDAILFAKND 70 80 90 100 110 120 YKLLPESQQQ IQTMAAKLAS TGLTHARMDG HTDNYGEDSY NEGLSLKRAN VVADAWAMGG 130 140 150 160 QIPRSNLTTQ GLGKKYPIAS NKTAQGRAEN RRVAVVITTP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of an Escherichia coli operon containing genes for the tRNA(m1G)methyltransferase, the ribosomal proteins S16 and L19 and a 21-K polypeptide." Bystroem A.S., Hjalmarsson K.J., Wikstroem P.M., Bjoerk G.R. EMBO J. 2:899-905(1983) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T. , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T. DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]	"The structural gene (trmD) for the tRNA(m1G)methyltransferase is part of a four polypeptide operon in Escherichia coli K-12." Bystroem A.S., Bjoerk G.R. Mol. Gen. Genet. 188:447-454(1982) [PubMed] [Europe PMC] [Abstract] Cited for: SHOWS THAT THE PROTEIN IS EXPRESSED.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X01818 Genomic DNA. Translation: CAA25961.1. Different initiation. U00096 Genomic DNA. Translation: AAC75654.1. AP009048 Genomic DNA. Translation: BAA16490.1.
PIR	H65038.
RefSeq	NP_417096.1. NC_000913.2. YP_490828.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P07021.
SMR	P07021. Positions 48-158.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-12056N.
IntAct	P07021. 1 interaction.
MINT	MINT-1275809.
STRING	511145.b2605.
Proteomic databases
PRIDE	P07021.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC75654; AAC75654; b2605. BAA16490; BAA16490; BAA16490.
GeneID	12931623. 947094.
KEGG	ecj:Y75_p2553. eco:b2605.
PATRIC	32120609. VBIEscCol129921_2703.
Organism-specific databases
EchoBASE	EB1141.
EcoGene	EG11152. yfiB.
Phylogenomic databases
eggNOG	COG2885.
HOGENOM	HOG000189913.
OMA	DNRTSAG.
ProtClustDB	PRK09967.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11152-MONOMER. ECOL316407:JW2586-MONOMER.
Gene expression databases
Genevestigator	P07021.
Family and domain databases
Gene3D	3.30.1330.60. 1 hit.
InterPro	IPR006664. OMP_bac. IPR006665. OmpA/MotB_C. [Graphical view]
Pfam	PF00691. OmpA. 1 hit. [Graphical view]
PRINTS	PR01021. OMPADOMAIN.
SUPFAM	SSF103088. OmpA/MotB_C. 1 hit.
PROSITE	PS01068. OMPA_1. False negative. PS51123. OMPA_2. 1 hit. PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YFIB_ECOLI

Accession

Primary (citable) accession number: P07021

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1988
Last sequence update:	August 1, 1992
Last modified:	May 1, 2013
This is version 112 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program