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Protein

HTH-type transcriptional regulator DicA

Gene

dicA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

This protein is a repressor of division inhibition gene dicB.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi23 – 42H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

  • DNA binding Source: EcoCyc
  • sequence-specific DNA binding Source: InterPro

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processCell cycle, Cell division, Transcription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG10226-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator DicA
Alternative name(s):
Repressor protein of division inhibition gene dicA
Gene namesi
Name:dicA
Ordered Locus Names:b1570, JW1562
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10226 dicA

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001497251 – 135HTH-type transcriptional regulator DicAAdd BLAST135

Proteomic databases

PaxDbiP06966
PRIDEiP06966

Interactioni

Protein-protein interaction databases

IntActiP06966, 5 interactors
STRINGi316385.ECDH10B_1702

Structurei

3D structure databases

ProteinModelPortaliP06966
SMRiP06966
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 66HTH cro/C1-typePROSITE-ProRule annotationAdd BLAST55

Phylogenomic databases

eggNOGiENOG41087BU Bacteria
COG1396 LUCA
HOGENOMiHOG000120198
InParanoidiP06966
KOiK22300
OMAiNESIGAR

Family and domain databases

CDDicd00093 HTH_XRE, 1 hit
InterProiView protein in InterPro
IPR001387 Cro/C1-type_HTH
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF01381 HTH_3, 1 hit
SMARTiView protein in SMART
SM00530 HTH_XRE, 1 hit
SUPFAMiSSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS50943 HTH_CROC1, 1 hit

Sequencei

Sequence statusi: Complete.

P06966-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKNLTIGE RIRYRRKNLK HTQRSLAKAL KISHVSVSQW ERGDSEPTGK
60 70 80 90 100
NLFALSKVLQ CSPTWILFGD EDKQPTPPVE KPVALSPKEL ELLELFNALP
110 120 130
ESEQDTQLAE MRARVKNFNK LFEELLKARQ RTNKR
Length:135
Mass (Da):15,656
Last modified:April 1, 1988 - v1
Checksum:iF95F3BB666D6C6B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07465 Genomic DNA Translation: CAA30349.1
U00096 Genomic DNA Translation: AAC74643.1
AP009048 Genomic DNA Translation: BAA15275.1
PIRiS05260 BVECDA
RefSeqiNP_416088.1, NC_000913.3
WP_000448564.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74643; AAC74643; b1570
BAA15275; BAA15275; BAA15275
GeneIDi946241
KEGGiecj:JW1562
eco:b1570
PATRICifig|1411691.4.peg.693

Similar proteinsi

Entry informationi

Entry nameiDICA_ECOLI
AccessioniPrimary (citable) accession number: P06966
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: March 28, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health