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P06703

- S10A6_HUMAN

UniProt

P06703 - S10A6_HUMAN

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Protein
Protein S100-A6
Gene
S100A6, CACY
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi20 – 331411 Publication
Add
BLAST
Calcium bindingi61 – 721221 Publication
Add
BLAST

GO - Molecular functioni

  1. S100 protein binding Source: UniProtKB
  2. calcium ion binding Source: UniProtKB
  3. calcium-dependent protein binding Source: UniProtKB
  4. ion transmembrane transporter activity Source: Ensembl
  5. protein binding Source: UniProtKB
  6. protein homodimerization activity Source: UniProtKB
  7. tropomyosin binding Source: UniProtKB
  8. zinc ion binding Source: Ensembl

GO - Biological processi

  1. axonogenesis Source: UniProtKB
  2. positive regulation of fibroblast proliferation Source: UniProtKB
  3. signal transduction Source: UniProtKB
Complete GO annotation...

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein S100-A6
Alternative name(s):
Calcyclin
Growth factor-inducible protein 2A9
MLN 4
Prolactin receptor-associated protein
Short name:
PRA
S100 calcium-binding protein A6
Gene namesi
Name:S100A6
Synonyms:CACY
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:10496. S100A6.

Subcellular locationi

Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side 3 Publications

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. cytosol Source: UniProtKB
  3. extracellular vesicular exosome Source: UniProt
  4. extrinsic component of cytoplasmic side of plasma membrane Source: UniProtKB
  5. nuclear envelope Source: UniProtKB
  6. nucleus Source: UniProtKB
  7. perinuclear region of cytoplasm Source: UniProtKB
  8. ruffle Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane, Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34908.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9090Protein S100-A6
PRO_0000143984Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei40 – 401N6-acetyllysine1 Publication
Modified residuei47 – 471N6-acetyllysine; alternate By similarity
Modified residuei47 – 471N6-succinyllysine; alternate By similarity

Post-translational modificationi

The N-terminus is blocked.

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiP06703.
PaxDbiP06703.
PeptideAtlasiP06703.
PRIDEiP06703.

2D gel databases

DOSAC-COBS-2DPAGEP06703.

PTM databases

PhosphoSiteiP06703.

Expressioni

Inductioni

Preferentially expressed when quiescent fibroblasts are stimulated to proliferate. It is inducible by growth factors and overexpressed in acute myeloid leukemias.

Gene expression databases

BgeeiP06703.
CleanExiHS_S100A6.
GenevestigatoriP06703.

Organism-specific databases

HPAiCAB002601.
CAB040549.
HPA007575.

Interactioni

Subunit structurei

Homodimer; head to tail assembly of 2 subunits. Interacts with CACYBP in a calcium-dependent manner. Interacts with ANXA2 and ANXA11 (via N-terminus). Interacts with SUGT1. Interacts with TP53; has higher affinity for TP53 that is phosphorylated on its N-terminal domain, and lower affinity for TP53 that is phosphorylated on its C-terminal domain. Interacts with tropomyosin. Interacts with FKBP4. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity.6 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
FKBP4Q027903EBI-352877,EBI-1047444
KPNA2P522923EBI-352877,EBI-349938
MDM2Q009872EBI-352877,EBI-389668
PPIDP268823EBI-352877,EBI-6477155From a different organism.
S100BP042715EBI-352877,EBI-458391

Protein-protein interaction databases

BioGridi112185. 19 interactions.
IntActiP06703. 10 interactions.
MINTiMINT-3005220.
STRINGi9606.ENSP00000357708.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi4 – 2017
Beta strandi22 – 243
Beta strandi28 – 303
Helixi31 – 4111
Helixi45 – 473
Helixi51 – 6212
Turni63 – 653
Beta strandi67 – 693
Helixi70 – 8415
Helixi86 – 883

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1K8UX-ray1.15A1-90[»]
1K96X-ray1.44A1-90[»]
1K9KX-ray1.76A/B1-90[»]
1K9PX-ray1.90A1-90[»]
ProteinModelPortaliP06703.
SMRiP06703. Positions 2-90.

Miscellaneous databases

EvolutionaryTraceiP06703.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 4736EF-hand 1
Add
BLAST
Domaini48 – 8336EF-hand 2
Add
BLAST

Sequence similaritiesi

Belongs to the S-100 family.
Contains 2 EF-hand domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG40006.
HOGENOMiHOG000246968.
HOVERGENiHBG001479.
InParanoidiP06703.
OMAiCHLIRIS.
OrthoDBiEOG78WKVD.
PhylomeDBiP06703.
TreeFamiTF332727.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR001751. S100/CaBP-9k_CS.
IPR013787. S100_Ca-bd_sub.
[Graphical view]
PfamiPF01023. S_100. 1 hit.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.
PS00303. S100_CABP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P06703-1 [UniParc]FASTAAdd to Basket

« Hide

MACPLDQAIG LLVAIFHKYS GREGDKHTLS KKELKELIQK ELTIGSKLQD   50
AEIARLMEDL DRNKDQEVNF QEYVTFLGAL ALIYNEALKG 90
Length:90
Mass (Da):10,180
Last modified:January 1, 1988 - v1
Checksum:i860CBB1416ACBCA1
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti27 – 271H → R.
Corresponds to variant rs11974 [ dbSNP | Ensembl ].
VAR_011982
Natural varianti69 – 691N → S.
Corresponds to variant rs1802581 [ dbSNP | Ensembl ].
VAR_011983
Natural varianti83 – 831I → T.
Corresponds to variant rs1802582 [ dbSNP | Ensembl ].
VAR_011984
Natural varianti90 – 901G → D.
Corresponds to variant rs2228293 [ dbSNP | Ensembl ].
VAR_029281

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M14300 mRNA. Translation: AAA35886.1.
J02763 Genomic DNA. Translation: AAA51905.1.
M18981 mRNA. Translation: AAA51906.1.
AY034480 Genomic DNA. Translation: AAK59702.1.
BT006965 mRNA. Translation: AAP35611.1.
BX470102 Genomic DNA. Translation: CAI14752.1.
CH471121 Genomic DNA. Translation: EAW53318.1.
CH471121 Genomic DNA. Translation: EAW53320.1.
CH471121 Genomic DNA. Translation: EAW53321.1.
CH471121 Genomic DNA. Translation: EAW53322.1.
CH471121 Genomic DNA. Translation: EAW53323.1.
CH471121 Genomic DNA. Translation: EAW53324.1.
CH471121 Genomic DNA. Translation: EAW53325.1.
CH471121 Genomic DNA. Translation: EAW53326.1.
BC001431 mRNA. Translation: AAH01431.1.
BC009017 mRNA. Translation: AAH09017.1.
CCDSiCCDS1040.1.
PIRiA28363. BCHUY.
RefSeqiNP_055439.1. NM_014624.3.
UniGeneiHs.275243.

Genome annotation databases

EnsembliENST00000368719; ENSP00000357708; ENSG00000197956.
ENST00000368720; ENSP00000357709; ENSG00000197956.
ENST00000496817; ENSP00000473589; ENSG00000197956.
GeneIDi6277.
KEGGihsa:6277.
UCSCiuc001fbw.1. human.

Polymorphism databases

DMDMi116509.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M14300 mRNA. Translation: AAA35886.1 .
J02763 Genomic DNA. Translation: AAA51905.1 .
M18981 mRNA. Translation: AAA51906.1 .
AY034480 Genomic DNA. Translation: AAK59702.1 .
BT006965 mRNA. Translation: AAP35611.1 .
BX470102 Genomic DNA. Translation: CAI14752.1 .
CH471121 Genomic DNA. Translation: EAW53318.1 .
CH471121 Genomic DNA. Translation: EAW53320.1 .
CH471121 Genomic DNA. Translation: EAW53321.1 .
CH471121 Genomic DNA. Translation: EAW53322.1 .
CH471121 Genomic DNA. Translation: EAW53323.1 .
CH471121 Genomic DNA. Translation: EAW53324.1 .
CH471121 Genomic DNA. Translation: EAW53325.1 .
CH471121 Genomic DNA. Translation: EAW53326.1 .
BC001431 mRNA. Translation: AAH01431.1 .
BC009017 mRNA. Translation: AAH09017.1 .
CCDSi CCDS1040.1.
PIRi A28363. BCHUY.
RefSeqi NP_055439.1. NM_014624.3.
UniGenei Hs.275243.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1K8U X-ray 1.15 A 1-90 [» ]
1K96 X-ray 1.44 A 1-90 [» ]
1K9K X-ray 1.76 A/B 1-90 [» ]
1K9P X-ray 1.90 A 1-90 [» ]
ProteinModelPortali P06703.
SMRi P06703. Positions 2-90.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 112185. 19 interactions.
IntActi P06703. 10 interactions.
MINTi MINT-3005220.
STRINGi 9606.ENSP00000357708.

PTM databases

PhosphoSitei P06703.

Polymorphism databases

DMDMi 116509.

2D gel databases

DOSAC-COBS-2DPAGE P06703.

Proteomic databases

MaxQBi P06703.
PaxDbi P06703.
PeptideAtlasi P06703.
PRIDEi P06703.

Protocols and materials databases

DNASUi 6277.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000368719 ; ENSP00000357708 ; ENSG00000197956 .
ENST00000368720 ; ENSP00000357709 ; ENSG00000197956 .
ENST00000496817 ; ENSP00000473589 ; ENSG00000197956 .
GeneIDi 6277.
KEGGi hsa:6277.
UCSCi uc001fbw.1. human.

Organism-specific databases

CTDi 6277.
GeneCardsi GC01M153507.
HGNCi HGNC:10496. S100A6.
HPAi CAB002601.
CAB040549.
HPA007575.
MIMi 114110. gene.
neXtProti NX_P06703.
PharmGKBi PA34908.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG40006.
HOGENOMi HOG000246968.
HOVERGENi HBG001479.
InParanoidi P06703.
OMAi CHLIRIS.
OrthoDBi EOG78WKVD.
PhylomeDBi P06703.
TreeFami TF332727.

Miscellaneous databases

ChiTaRSi S100A6. human.
EvolutionaryTracei P06703.
GeneWikii S100A6.
GenomeRNAii 6277.
NextBioi 24365.
PROi P06703.
SOURCEi Search...

Gene expression databases

Bgeei P06703.
CleanExi HS_S100A6.
Genevestigatori P06703.

Family and domain databases

Gene3Di 1.10.238.10. 1 hit.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR001751. S100/CaBP-9k_CS.
IPR013787. S100_Ca-bd_sub.
[Graphical view ]
Pfami PF01023. S_100. 1 hit.
[Graphical view ]
PROSITEi PS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.
PS00303. S100_CABP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of the cDNA for a growth factor-inducible gene with strong homology to S-100, a calcium-binding protein."
    Calabretta B., Battini R., Kaczmarek L., de Riel J.K., Baserga R.
    J. Biol. Chem. 261:12628-12632(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Fibroblast.
  2. "Structural and functional analysis of a growth-regulated gene, the human calcyclin."
    Ferrari S., Calabretta B., Deriel J.K., Battini R., Ghezzo F., Lauret E., Griffin C., Emanuel B.S., Gurrieri F., Baserga R.
    J. Biol. Chem. 262:8325-8332(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Cloning and characterization of a cDNA encoding a highly conserved, putative calcium binding protein, identified by an anti-prolactin receptor antiserum."
    Murphy L.C., Murphy L.J., Tsuyuki D., Duckworth M.L., Shiu R.P.C.
    J. Biol. Chem. 263:2397-2401(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  4. "Cloning of human calcyclin and calcyclin binding protein (CacyBP)."
    Wu J., Liu W., Zhou Y., Zhao Z., Peng X., Yuan J., Qiang B.
    Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  5. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  6. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Placenta.
  9. Cited for: PROTEIN SEQUENCE OF 27-31 AND 48-89.
    Tissue: Platelet.
  10. "Identification of a cell cycle-dependent gene product as a sialic acid-binding protein."
    Gabius H.J., Bardosi A., Gabius S., Hellmann K.P., Karas M., Kratzin H.
    Biochem. Biophys. Res. Commun. 163:506-512(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 57-74.
  11. "Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins."
    Nowotny M., Spiechowicz M., Jastrzebska B., Filipek A., Kitagawa K., Kuznicki J.
    J. Biol. Chem. 278:26923-26928(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH SUGT1.
  12. "Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope."
    Tomas A., Moss S.E.
    J. Biol. Chem. 278:20210-20216(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  13. "S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility."
    Nedjadi T., Kitteringham N., Campbell F., Jenkins R.E., Park B.K., Navarro P., Ashcroft F., Tepikin A., Neoptolemos J.P., Costello E.
    Br. J. Cancer 101:1145-1154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH ANXA2; ANXA11 AND TROPOMYOSIN, SUBCELLULAR LOCATION.
  14. "Posttranslational modifications affect the interaction of S100 proteins with tumor suppressor p53."
    van Dieck J., Teufel D.P., Jaulent A.M., Fernandez-Fernandez M.R., Rutherford T.J., Wyslouch-Cieszynska A., Fersht A.R.
    J. Mol. Biol. 394:922-930(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH TP53.
  15. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-40, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  16. "S100 proteins regulate the interaction of Hsp90 with cyclophilin 40 and FKBP52 through their tetratricopeptide repeats."
    Shimamoto S., Kubota Y., Tokumitsu H., Kobayashi R.
    FEBS Lett. 584:1119-1125(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH FKBP4.
  17. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  18. "S100 proteins modulate protein phosphatase 5 function: a link between CA2+ signal transduction and protein dephosphorylation."
    Yamaguchi F., Umeda Y., Shimamoto S., Tsuchiya M., Tokumitsu H., Tokuda M., Kobayashi R.
    J. Biol. Chem. 287:13787-13798(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH PPP5C, SUBCELLULAR LOCATION.
  19. "Crystal structures of S100A6 in the Ca(2+)-free and Ca(2+)-bound states: the calcium sensor mechanism of S100 proteins revealed at atomic resolution."
    Otterbein L.R., Kordowska J., Witte-Hoffmann C., Wang C.-L.A., Dominguez R.
    Structure 10:557-567(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS), SUBUNIT, CALCIUM-BINDING.

Entry informationi

Entry nameiS10A6_HUMAN
AccessioniPrimary (citable) accession number: P06703
Secondary accession number(s): D3DV39, Q5RHS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 1, 1988
Last modified: July 9, 2014
This is version 150 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

This protein co-purified with the prolactin receptor.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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