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Protein

Indoleacetamide hydrolase

Gene

iaaH

Organism
Pseudomonas savastanoi (Pseudomonas syringae pv. savastanoi)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

Pathwayi: auxin biosynthesis

This protein is involved in the pathway auxin biosynthesis, which is part of Plant hormone metabolism.
View all proteins of this organism that are known to be involved in the pathway auxin biosynthesis and in Plant hormone metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei71Charge relay systemBy similarity1
Active sitei146Charge relay systemBy similarity1
Active sitei170Acyl-ester intermediateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processAuxin biosynthesis

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-7681
UniPathwayiUPA00151

Names & Taxonomyi

Protein namesi
Recommended name:
Indoleacetamide hydrolase (EC:3.5.1.-)
Short name:
IAH
Alternative name(s):
Indole-3-acetamide hydrolase
Gene namesi
Name:iaaH
Encoded oniPlasmid pIAA10 Publication
OrganismiPseudomonas savastanoi (Pseudomonas syringae pv. savastanoi)
Taxonomic identifieri29438 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001052501 – 455Indoleacetamide hydrolaseAdd BLAST455

Structurei

3D structure databases

ProteinModelPortaliP06618
SMRiP06618
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family.Curated

Family and domain databases

Gene3Di3.90.1300.10, 1 hit
InterProiView protein in InterPro
IPR000120 Amidase
IPR020556 Amidase_CS
IPR023631 Amidase_dom
IPR036928 AS_sf
PANTHERiPTHR11895 PTHR11895, 1 hit
PfamiView protein in Pfam
PF01425 Amidase, 1 hit
SUPFAMiSSF75304 SSF75304, 1 hit
PROSITEiView protein in PROSITE
PS00571 AMIDASES, 1 hit

Sequencei

Sequence statusi: Complete.

P06618-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHEIITLESL CQALADGEIA AAELRERALD TEARLARLNC FIREGDAVSQ
60 70 80 90 100
FGEADHAMKG TPLWGMPVSF KDNICVRGLP LTAGTRGMSG FVSDQDAAIV
110 120 130 140 150
SQLRALGAVV AGKNNMHELS FGVTSINPHW GTVGNPVAPG YCAGGSSGGS
160 170 180 190 200
AAAVASGIVP LSVGTDTGGS IRIPAAFCGI TGFRPTTGRW STAGIIPVSH
210 220 230 240 250
TKDCVGLLTR TAGDAGFLYG LLSGKQQSFP LSRTAPCRIG LPVSMWSDLD
260 270 280 290 300
GEVERACVNA LSLLRKTGFE FIEIDDADIV ELNQTLTFTV PLYEFFADLA
310 320 330 340 350
QSLLSLGWKH GIHHIFAQVD DANVKGIINH HLGEGAIKPA HYLSSLQNGE
360 370 380 390 400
LLKRKMDELF ARHNIELLGY PTVPCRVPHL DHADRPEFFS QAIRNTDLAS
410 420 430 440 450
NAMLPSITIP VGPEGRLPVG LSFDALRGRD ALLLSRVSAI EQVLGFVRKV

LPHTT
Length:455
Mass (Da):48,578
Last modified:January 1, 1988 - v1
Checksum:i85999DD7684D0E53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M11035 Genomic DNA Translation: AAA25853.1
PIRiB25493

Similar proteinsi

Entry informationi

Entry nameiHYIN_PSESS
AccessioniPrimary (citable) accession number: P06618
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 1, 1988
Last modified: October 25, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid
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Main funding by: National Institutes of Health