P06610 (BTUE_ECOLI) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 97.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Vitamin B12 transport periplasmic protein BtuE EC=1.-.-.- | ||||
| Gene names |
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| Organism | Escherichia coli (strain K12) | ||||
| Taxonomic identifier | 83333 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 183 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Not essential for B12 transport; however, it is an auxiliary component of the transport system. |
| Subcellular location | Periplasm Probable. |
| Sequence similarities | Belongs to the glutathione peroxidase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cobalt transport Ion transport Transport |
| Cellular component | Periplasm |
| Ligand | Cobalt |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | cobalt ion transport Inferred from electronic annotation. Source: UniProtKB-KW response to hydroperoxideInferred from expression pattern. Source: EcoCyc |
| Cellular component | periplasmic space Inferred from direct assay. Source: EcoliWiki |
| Molecular function | glutathione peroxidase activity Inferred from direct assay. Source: EcoCyc thioredoxin peroxidase activityInferred from direct assay. Source: EcoCyc |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 183 | 183 | Vitamin B12 transport periplasmic protein BtuE | PRO_0000066664 | |||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Nucleotide sequence of the btuCED genes involved in vitamin B12 transport in Escherichia coli and homology with components of periplasmic-binding-protein-dependent transport systems." Friedrich M.J., Deveaux L.C., Kadner R.J. J. Bacteriol. 167:928-934(1986) [PubMed: 3528129] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. Horiuchi T.DNA Res. 3:363-377(1996) [PubMed: 9097039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911. |
| [3] | "The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076. |
| [4] | "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | M14031 Genomic DNA. Translation: AAA23527.1. U00096 Genomic DNA. Translation: AAC74780.1. AP009048 Genomic DNA. Translation: BAA15478.1. |
| PIR | QRECBE. F64929. |
| RefSeq | NP_416225.1. NC_000913.2. |
3D structure databases | |
| ProteinModelPortal | P06610. |
| SMR | P06610. Positions 3-183. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P06610. 17 interactions. |
Protein family/group databases | |
| PeroxiBase | 3987. EcoGPx01. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBESCT00000004469; EBESCP00000004469; EBESCG00000003646. EBESCT00000018139; EBESCP00000017430; EBESCG00000017194. |
| GeneID | 945915. |
| GenomeReviews | Gene locus JW1700 in contig AP009048_GR. Gene locus b1710 in contig U00096_GR. |
| KEGG | ecj:JW1700. eco:b1710. |
| PATRIC | 32118726. VBIEscCol129921_1781. |
Organism-specific databases | |
| EchoBASE | EB0127. |
| EcoGene | EG10129. btuE. |
Phylogenomic databases | |
| eggNOG | COG0386. |
| GeneTree | EBGT00050000010776. |
| HOGENOM | HBG648990. |
| OMA | QQKETDF. |
| PhylomeDB | P06610. |
| ProtClustDB | PRK10606. |
Enzyme and pathway databases | |
| BioCyc | EcoCyc:BTUE-MONOMER. MetaCyc:BTUE-MONOMER. |
Gene expression databases | |
| Genevestigator | P06610. |
Family and domain databases | |
| InterPro | IPR000889. Glutathione_peroxidase. IPR012336. Thioredoxin-like_fold. [Graphical view] |
| Gene3D | G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. |
| KO | K00432. |
| PANTHER | PTHR11592. Glut_peroxidase. 1 hit. |
| Pfam | PF00255. GSHPx. 1 hit. [Graphical view] |
| PIRSF | PIRSF000303. Glutathion_perox. 1 hit. |
| PRINTS | PR01011. GLUTPROXDASE. |
| SUPFAM | SSF52833. Thiordxn-like_fd. 1 hit. |
| PROSITE | PS00460. GLUTATHIONE_PEROXID_1. 1 hit. PS00763. GLUTATHIONE_PEROXID_2. 1 hit. PS51355. GLUTATHIONE_PEROXID_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BTUE_ECOLI | ||||||||
| Accession | Primary (citable) accession number: P06610 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Escherichia coli Escherichia coli (strain K12): entries and cross-references to EcoGene |
| SIMILARITY comments Index of protein domains and families |

Clusters with