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Protein

Heat shock protein Hsp-16.41

Gene

hsp-16.41

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • unfolded protein binding Source: WormBase

GO - Biological processi

  • defense response to Gram-negative bacterium Source: WormBase
  • endoplasmic reticulum unfolded protein response Source: WormBase
  • response to heat Source: WormBase

Keywordsi

Biological processStress response

Enzyme and pathway databases

ReactomeiR-CEL-3371571 HSF1-dependent transactivation
R-CEL-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein Hsp-16.41
Gene namesi
Name:hsp-16.41
Synonyms:hsp16-41
ORF Names:Y46H3A.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiY46H3A.2 ; CE22003 ; WBGene00002018 ; hsp-16.41

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001259601 – 143Heat shock protein Hsp-16.41Add BLAST143

Proteomic databases

EPDiP06581
PaxDbiP06581
PeptideAtlasiP06581

Expressioni

Gene expression databases

BgeeiWBGene00002018

Interactioni

GO - Molecular functioni

  • unfolded protein binding Source: WormBase

Protein-protein interaction databases

IntActiP06581, 2 interactors
STRINGi6239.Y46H3A.2

Structurei

3D structure databases

ProteinModelPortaliP06581
SMRiP06581
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 140sHSPPROSITE-ProRule annotationAdd BLAST106

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3591 Eukaryota
ENOG410YERS LUCA
GeneTreeiENSGT00760000119238
HOGENOMiHOG000233954
InParanoidiP06581
OMAiSKNERII
OrthoDBiEOG091G0USC
PhylomeDBiP06581

Family and domain databases

Gene3Di2.60.40.790, 1 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR001436 Alpha-crystallin/HSP
IPR031107 HSP20
IPR008978 HSP20-like_chaperone
PANTHERiPTHR11527 PTHR11527, 1 hit
PfamiView protein in Pfam
PF00011 HSP20, 1 hit
PIRSFiPIRSF036514 Sm_HSP_B1, 1 hit
PRINTSiPR00299 ACRYSTALLIN
SUPFAMiSSF49764 SSF49764, 1 hit
PROSITEiView protein in PROSITE
PS01031 SHSP, 1 hit

Sequencei

Sequence statusi: Complete.

P06581-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLMLRSPYSD SNALDHFLDE LTGSVQFPYW RNADHNSFNF SDNIGEIVND
60 70 80 90 100
ESKFSVQLDV SHFKPENLKI KLDGRELKIE GIQETKSEHG YLKRSFSKMI
110 120 130 140
LLPEDADLPS VKSAISNEGK LQIEAPKKTN SSRSIPINFV AKH
Length:143
Mass (Da):16,252
Last modified:January 1, 1988 - v1
Checksum:iC1D0F59D26E36C24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14334 Genomic DNA Translation: AAA28070.1 Sequence problems.
FO081307 Genomic DNA Translation: CCD70650.1
X01577 mRNA Translation: CAA25732.1
PIRiA25199 HHKW41
RefSeqiNP_872116.2, NM_182316.4
UniGeneiCel.24670

Genome annotation databases

EnsemblMetazoaiY46H3A.2; Y46H3A.2; WBGene00002018
GeneIDi178660
KEGGicel:CELE_Y46H3A.2
UCSCiY46H3A.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiHSP16_CAEEL
AccessioniPrimary (citable) accession number: P06581
Secondary accession number(s): P02514
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 1, 1988
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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