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Protein

Sporulation initiation phosphotransferase B

Gene

spo0B

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Key element in the phosphorelay regulating sporulation initiation. Acts on spo0A. Mediates reversible phosphoryl transfer from spo0F to spo0A.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processSensory transduction, Sporulation

Enzyme and pathway databases

BioCyciBSUB:BSU27930-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Sporulation initiation phosphotransferase B (EC:2.7.-.-)
Alternative name(s):
Stage 0 sporulation protein B
Stage 0 sporulation protein D
Gene namesi
Name:spo0B
Synonyms:spo0D
Ordered Locus Names:BSU27930
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi30H → A: Loss of sporulation. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000720521 – 192Sporulation initiation phosphotransferase BAdd BLAST192

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei30Phosphohistidine1 Publication1

Post-translational modificationi

Phosphorylated by spo0F.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP06535
PRIDEiP06535

PTM databases

iPTMnetiP06535

Expressioni

Developmental stagei

Expressed during sporulation.

Interactioni

Subunit structurei

Homodimer. Dimerization is essential for activity as both monomers contribute to the formation of the active site.

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100015266

Structurei

Secondary structure

1192
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi15 – 44Combined sources30
Helixi48 – 69Combined sources22
Turni70 – 72Combined sources3
Helixi74 – 82Combined sources9
Helixi83 – 85Combined sources3
Beta strandi89 – 99Combined sources11
Turni104 – 106Combined sources3
Helixi107 – 124Combined sources18
Beta strandi127 – 129Combined sources3
Beta strandi132 – 138Combined sources7
Beta strandi142 – 154Combined sources13
Helixi159 – 161Combined sources3
Helixi163 – 166Combined sources4
Beta strandi175 – 180Combined sources6
Beta strandi182 – 191Combined sources10

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1F51X-ray3.00A/B/C/D11-192[»]
1IXMX-ray2.60A/B1-192[»]
2FTKX-ray3.05A/B/C/D1-192[»]
ProteinModelPortaliP06535
SMRiP06535
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP06535

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000097276
KOiK06375
OMAiRHARHDW

Family and domain databases

Gene3Di3.30.565.30, 1 hit
InterProiView protein in InterPro
IPR016120 Sig_transdc_His_kin_SpoOB
IPR037100 Spo0B_C_sf
IPR016122 SpoOB_C
PfamiView protein in Pfam
PF14682 SPOB_ab, 1 hit
SMARTiView protein in SMART
SM01317 SPOB_ab, 1 hit
SUPFAMiSSF55890 SSF55890, 1 hit

Sequencei

Sequence statusi: Complete.

P06535-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDVSKNQEE NISDTALTNE LIHLLGHSRH DWMNKLQLIK GNLSLQKYDR
60 70 80 90 100
VFEMIEEMVI DAKHESKLSN LKTPHLAFDF LTFNWKTHYM TLEYEVLGEI
110 120 130 140 150
KDLSAYDQKL AKLMRKLFHL FDQAVSRESE NHLTVSLQTD HPDRQLILYL
160 170 180 190
DFHGAFADPS AFDDIRQNGY EDVDIMRFEI TSHECLIEIG LD
Length:192
Mass (Da):22,543
Last modified:January 1, 1988 - v1
Checksum:i3A9A38B5FFB55647
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02655 Genomic DNA Translation: CAA26489.1
M24537 Genomic DNA Translation: AAA22504.1
K02664 Genomic DNA Translation: AAB05348.1
AL009126 Genomic DNA Translation: CAB14753.1
PIRiA22974 SZBS0B
RefSeqiNP_390671.1, NC_000964.3
WP_004399131.1, NZ_JNCM01000036.1

Genome annotation databases

EnsemblBacteriaiCAB14753; CAB14753; BSU27930
GeneIDi935956
KEGGibsu:BSU27930
PATRICifig|224308.179.peg.3034

Similar proteinsi

Entry informationi

Entry nameiSP0B_BACSU
AccessioniPrimary (citable) accession number: P06535
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 1, 1988
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

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