P06516 (CAPP_SYNP6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31

Gene names

Name:	ppc
Ordered Locus Names:	syc1846_d

Organism

Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) [Complete proteome] [HAMAP]

Taxonomic identifier

269084 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechococcus › Synechococcus elongatus

Protein attributes

Sequence length	1053 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the PEPCase type 1 family.

Ontologies

Keywords
Biological process	Carbon dioxide fixation
Ligand	Magnesium
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1053	1053	Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595		PRO_0000166638
Sites
	Active site	246	1	By similarity
	Active site	699	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P06516 [UniParc]. Last modified January 1, 1988. Version 1. Checksum: 1EDDA7DD8DFFD364	FASTA	1,053	121,084
	10 20 30 40 50 60 MLAVSLRDHG FPSATVQIRP AFCVQSDVVG SGNPPRMNYC QNARTAMSAA LQSSDDAFRT 70 80 90 100 110 120 VSSPLATDLD LSSPLEFFLR HRLTVVEELW EVVLRQECGQ ELVDILTQLR DLTSPEGQAP 130 140 150 160 170 180 EVGGEALVQV IETLELSDAI RAARAFALYF QLINIVEQHY EQTQYQLAYE RSRLEPLPGP 190 200 210 220 230 240 DESPEGLHTI EIPQHQLDPF AAVIPLNQDP ATFQTLFPRL RQLNVPPQMI QELTDRLDIR 250 260 270 280 290 300 LVFTAHPTEI VRHTIRDKQR RIAYLLRQLD ELETGKNRGF RELEAQNIRQ QLTEEIRLWW 310 320 330 340 350 360 RTDELHQFKP TVLDEVDYAL HYFQEVLFEA IPLLYQRFRL ALQGTFPDLQ PPRYNFCQFG 370 380 390 400 410 420 SWVGSDRDGN PSVTSAVTWQ TACYQRSLVL DRYITAVEHL RNVLSLSMHW SEVLPELLSS 430 440 450 460 470 480 LEQESMLFPE TYEQLAVRYR QEPYRLKLSY ILERLHNTRD RNTRLQQQQE KDPTTPLPEY 490 500 510 520 530 540 RDGTLYQAGT AFLEDLKLIQ HNLKQTGLSC YELEKLICQV EIFGFNLVHL DIRQESSRHS 550 560 570 580 590 600 DAINEICEYL QILPQPYNEL SEAERTAWLV QELKTRRPLV PARMPFSEST REIIETLRMV 610 620 630 640 650 660 KQLQEEFGEA ACQTYIISMS RELSDLLEVL LLAKEVGLYD PVTGKSSLQV IPLFETVEDL 670 680 690 700 710 720 QNAPRVMTAL FELPFYTQLN PTQSEPLQEV MLGYSDSNKD SGFLSSNWEI HKAQKALGTV 730 740 750 760 770 780 ARDHRVKLRI FHGRGGSVGR GGGPAYEAIL AQPGRTTDGR IKITEQGEVL ASKYALPELA 790 800 810 820 830 840 LYNLETITTA VIQSSLLGSG FDDIEPWNQI MEELAARSRR HYRALVYEQP DLVDFFNQVT 850 860 870 880 890 900 PIEEISKLQI SSRPARRKTG KRDLGSLRAI PWVFSWTQSR FLLPSWYGVG TALQEFLQER 910 920 930 940 950 960 PEQNLNLLRY FYEKWPFFRM VISKVEMTLA KVDLQIAHHY VHELANPEDQ ERFERVFSQI 970 980 990 1000 1010 1020 AAEFQLTCHL VLTITNHGRL LDGDPELQRS VQLRNGTIVP LGFLQVALLK RLRQYRQQTE 1030 1040 1050 TTGLMRSRYS KGELLRGALL TINGIAAGMR NTG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of the phosphoenolpyruvate carboxylase gene of the cyanobacterium Anacystis nidulans." Katagiri F., Kodaki T., Fujita N., Izui K., Katsuki H. Gene 38:265-269(1985) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization." Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M. Photosyn. Res. 93:55-67(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27144 / PCC 6301 / SAUG 1402/1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M11198 Genomic DNA. Translation: AAA22052.1. AP008231 Genomic DNA. Translation: BAD80036.1.
PIR	QYYC. A24517.
RefSeq	YP_172556.1. NC_006576.1.
3D structure databases
ProteinModelPortal	P06516.
ModBase	Search...
Protein-protein interaction databases
STRING	269084.syc1846_d.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAD80036; BAD80036; syc1846_d.
GeneID	3199626.
KEGG	syc:syc1846_d.
PATRIC	32489743. VBISynElo117686_2108.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2352.
HOGENOM	HOG000238647.
KO	K01595.
OMA	AIPWVFG.
ProtClustDB	PRK00009.
Family and domain databases
HAMAP	MF_00595. PEPcase_type1.
InterPro	IPR021135. PEP_COase. IPR018129. PEP_COase_AS. IPR022805. PEP_COase_bac/pln-type. IPR015813. Pyrv/PenolPyrv_Kinase. [Graphical view]
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPP_SYNP6

Accession

Primary (citable) accession number: P06516

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 1, 1988
Last sequence update:	January 1, 1988
Last modified:	May 1, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program