Reviewed, UniProtKB/Swiss-Prot P06495 (CBP_SACER)

Names and origin

Protein names	Recommended name:     Calerythrin Alternative name(s):     Calcium-binding protein
Organism	Saccharopolyspora erythraea (Streptomyces erythraeus)
Taxonomic identifier	1836 [NCBI]
Taxonomic lineage	Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous	This protein binds calcium.
Sequence similarities	Contains 4 EF-hand domains.

Ontologies

Keywords
Domain	Repeat
Ligand	Calcium
Technical term	3D-structure
Gene Ontology (GO)
Molecular function	calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 177

177

Calerythrin

PRO_0000073580

Regions

Domain

5 – 40

36

EF-hand 1

Domain

45 – 90

46

EF-hand 2

Domain

100 – 134

35

EF-hand 3

Domain

134 – 169

36

EF-hand 4

Calcium binding

18 – 29

12

1 Potential

Calcium binding

113 – 124

12

2 Potential

Calcium binding

147 – 158

12

3 Potential

Secondary structure

1

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177

Helix Strand Turn

Details...

Helix

5 – 16

12

Beta strand

23 – 25

3

Helix

28 – 40

13

Beta strand

45 – 47

3

Helix

48 – 68

21

Helix

78 – 89

12

Beta strand

90 – 92

3

Helix

94 – 111

18

Beta strand

118 – 121

4

Helix

122 – 131

10

Helix

136 – 146

11

Beta strand

151 – 155

5

Helix

156 – 163

8

Beta strand

167 – 169

3

Sequences

	Sequence		Length	Mass (Da)
	P06495-1 [UniParc]. Last modified January 1, 1988. Version 1. Checksum: A2FE8EDDC19405DC	FASTA	177	19,245
	10 20 30 40 50 60 MTTAIASDRL KKRFDRWDFD GNGALERADF EKEAQHIAEA FGKDAGAAEV QTLKNAFGGL 70 80 90 100 110 120 FDYLAKEAGV GSDGSLTEEQ FIRVTENLIF EQGEASFNRV LGPVVKGTWG MCDKNADGQI 130 140 150 160 170 NADEFAAWLT ALGMSKAEAA EAFNQVDTNG NGELSLDELL TAVRDFHFGR LDVELLG

References

[1]	"A bacterial calcium-binding protein homologous to calmodulin." Swan D.G., Hale R.S., Dhillon N., Leadlay P.F. Nature 329:84-85(1987) [PubMed: 3627246] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Cloning, characterization, and heterologous expression of the Saccharopolyspora erythraea (Streptomyces erythraeus) gene encoding an EF-hand calcium-binding protein." Swan D.G., Cortes J., Hale R.S., Leadlay P.F. J. Bacteriol. 171:5614-5619(1989) [PubMed: 2676983] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

M29700 Genomic DNA. Translation: AAA26481.1.

PIR

A29289. A45916.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1NYA	NMR	-	A	2-177	[»]

ModBase

Search...

Family and domain databases

InterPro

IPR011992. EF-Hand_type.
IPR018248. EF_hand.
IPR018247. EF_HAND_1.
IPR018249. EF_HAND_2.
IPR002048. EF_hand_Ca_bd.
[Graphical view]

Gene3D

G3DSA:1.10.238.10. EF-Hand_type. 1 hit.

Pfam

PF00036. efhand. 2 hits.
[Graphical view]

ProDom

PD000012. EF-hand. 1 hit.
[Graphical view] [Entries sharing at least one domain]

SMART

SM00054. EFh. 3 hits.
[Graphical view]

PROSITE

PS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 3 hits.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

CBP_SACER

Accession

Primary (citable) accession number: P06495

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 1, 1988
Last sequence update:	January 1, 1988
Last modified:	June 16, 2009
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)