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Protein

ATP synthase subunit alpha, chloroplastic

Gene

atpA

Organism
Spinacia oleracea (Spinach)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei363Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi170 – 177ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alpha, chloroplasticUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
Encoded oniPlastid; Chloroplast
OrganismiSpinacia oleracea (Spinach)
Taxonomic identifieri3562 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesChenopodiaceaeChenopodioideaeAnserineaeSpinacia
Proteomesi
  • UP000054095 Componenti: Chloroplast

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CF(1), Chloroplast, Membrane, Plastid, Thylakoid

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL2366567

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001443921 – 507ATP synthase subunit alpha, chloroplasticAdd BLAST507

Proteomic databases

PRIDEiP06450

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has four main subunits: a, b, b' and c.UniRule annotation

Protein-protein interaction databases

MINTiP06450

Structurei

Secondary structure

1507
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni26 – 28Combined sources3
Beta strandi29 – 32Combined sources4
Beta strandi37 – 44Combined sources8
Beta strandi54 – 56Combined sources3
Beta strandi61 – 67Combined sources7
Beta strandi69 – 76Combined sources8
Helixi80 – 82Combined sources3
Beta strandi88 – 90Combined sources3
Beta strandi97 – 103Combined sources7
Beta strandi111 – 113Combined sources3
Beta strandi116 – 119Combined sources4
Beta strandi125 – 131Combined sources7
Beta strandi137 – 140Combined sources4
Turni152 – 157Combined sources6
Beta strandi167 – 175Combined sources9
Helixi176 – 185Combined sources10
Turni189 – 191Combined sources3
Beta strandi193 – 200Combined sources8
Helixi203 – 212Combined sources10
Turni213 – 217Combined sources5
Helixi218 – 220Combined sources3
Beta strandi221 – 227Combined sources7
Beta strandi229 – 231Combined sources3
Helixi233 – 235Combined sources3
Helixi238 – 252Combined sources15
Beta strandi256 – 262Combined sources7
Helixi264 – 277Combined sources14
Helixi284 – 286Combined sources3
Turni293 – 298Combined sources6
Helixi299 – 301Combined sources3
Beta strandi303 – 305Combined sources3
Turni307 – 310Combined sources4
Beta strandi313 – 316Combined sources4
Beta strandi319 – 321Combined sources3
Helixi330 – 336Combined sources7
Beta strandi339 – 342Combined sources4
Beta strandi347 – 353Combined sources7
Turni360 – 362Combined sources3
Helixi368 – 371Combined sources4
Helixi374 – 393Combined sources20
Turni394 – 396Combined sources3
Helixi397 – 399Combined sources3
Helixi405 – 421Combined sources17
Helixi431 – 442Combined sources12
Beta strandi445 – 449Combined sources5
Helixi451 – 467Combined sources17
Helixi470 – 479Combined sources10
Helixi484 – 498Combined sources15

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FX0X-ray3.20A1-507[»]
1KMHX-ray3.40A1-507[»]
ProteinModelPortaliP06450
SMRiP06450
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP06450

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

KOiK02111

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
PIRSFiPIRSF039088 F_ATPase_subunit_alpha, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

P06450-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATIRADEIS KIIRERIEGY NREVKVVNTG TVLQVGDGIA RIHGLDEVMA
60 70 80 90 100
GELVEFEEGT IGIALNLESN NVGVVLMGDG LMIQEGSSVK ATGRIAQIPV
110 120 130 140 150
SEAYLGRVIN ALAKPIDGRG EITASESRLI ESPAPGIMSR RSVYEPLQTG
160 170 180 190 200
LIAIDAMIPV GRGQRELIIG DRQTGKTAVA TDTILNQQGQ NVICVYVAIG
210 220 230 240 250
QKASSVAQVV TNFQERGAME YTIVVAETAD SPATLQYLAP YTGAALAEYF
260 270 280 290 300
MYRERHTLII YDDLSKQAQA YRQMSLLLRR PPGREAYPGD VFYLHSRLLE
310 320 330 340 350
RAAKLSSLLG EGSMTALPIV ETQAGDVSAY IPTNVISITD GQIFLSADLF
360 370 380 390 400
NAGIRPAINV GISVSRVGSA AQIKAMKKVA GKLKLELAQF AELEAFAQFA
410 420 430 440 450
SDLDKATQNQ LARGQRLREL LKQPQSAPLT VEEQVMTIYT GTNGYLDSLE
460 470 480 490 500
LDQVRKYLVE LRTYVKTNKP EFQEIISSTK TFTEEAEALL KEAIQEQMER

FLLQEQA
Length:507
Mass (Da):55,451
Last modified:August 1, 1988 - v1
Checksum:i97F0C73CE8B18417
GO

Sequence cautioni

The sequence CAB88710 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03775 Genomic DNA Translation: CAA27403.1
AJ400848 Genomic DNA Translation: CAB88710.1 Different initiation.
PIRiS00584 PWSPA
RefSeqiNP_054917.2, NC_002202.1

Genome annotation databases

GeneIDi2715575
KEGGisoe:2715575

Similar proteinsi

Entry informationi

Entry nameiATPA_SPIOL
AccessioniPrimary (citable) accession number: P06450
Secondary accession number(s): Q9LD04
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: August 1, 1988
Last modified: May 23, 2018
This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

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