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P06311 (KV311_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ig kappa chain V-III region IARC/BL41
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length128 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020
Chain21 – 128108Ig kappa chain V-III region IARC/BL41
PRO_0000015178

Regions

Region21 – 4323Framework-1
Region44 – 5411Complementarity-determining-1
Region55 – 6915Framework-2
Region70 – 767Complementarity-determining-2
Region77 – 10832Framework-3
Region109 – 1179Complementarity-determining-3
Region118 – 12811JK1 segment

Amino acid modifications

Disulfide bond43 ↔ 108 By similarity

Experimental info

Non-terminal residue1281

Sequences

Sequence LengthMass (Da)Tools
P06311 [UniParc].

Last modified January 1, 1988. Version 1.
Checksum: CC8957F0FE3B9012

FASTA12814,070
        10         20         30         40         50         60 
METPAQLLFL LLLWLPDTTG EIVLTQSPGT LSLSPGESAT LSCRASQSVS SNLAWYQQKR 

        70         80         90        100        110        120 
GQSPRLLIRD ASSRANGIPD RFSGSGSGTD FTLIISRLEP EDFAVYYCQQ YSTSPYTFGQ 


GTKLEIKR 

« Hide

References

[1]"Human immunoglobulin kappa light chain genes of subgroups II and III."
Klobeck H.G., Meindl A., Combriato G., Solomon A., Zachau H.G.
Nucleic Acids Res. 13:6499-6513(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z00021 Genomic DNA. Translation: CAA77316.1.
PIRK3HU41. A01899.

3D structure databases

ProteinModelPortalP06311.
SMRP06311. Positions 21-128.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSI43.001.
IMGTSearch...

Proteomic databases

PeptideAtlasP06311.
PRIDEP06311.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG018013.
PhylomeDBP06311.

Enzyme and pathway databases

ReactomeREACT_160300. Binding and Uptake of Ligands by Scavenger Receptors.
REACT_6900. Immune System.

Gene expression databases

GenevestigatorP06311.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamPF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00406. IGv. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35537734.

Entry information

Entry nameKV311_HUMAN
AccessionPrimary (citable) accession number: P06311
Entry history
Integrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 1, 1988
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.