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P06304

- PAHO_ANSAN

UniProt

P06304 - PAHO_ANSAN

Protein

Pancreatic hormone

Gene

PPY

Organism
Anser anser anser (Western graylag goose)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.

    Keywords - Molecular functioni

    Hormone

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pancreatic hormone
    Short name:
    PH
    Alternative name(s):
    Pancreatic polypeptide
    Short name:
    PP
    Gene namesi
    Name:PPY
    OrganismiAnser anser anser (Western graylag goose)
    Taxonomic identifieri8844 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeAnseriformesAnatidaeAnser

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Peptidei1 – 3636Pancreatic hormonePRO_0000044803Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei36 – 361Tyrosine amideBy similarity

    Keywords - PTMi

    Amidation

    Structurei

    3D structure databases

    ProteinModelPortaliP06304.
    SMRiP06304. Positions 1-36.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NPY family.Curated

    Phylogenomic databases

    HOVERGENiHBG096194.

    Family and domain databases

    InterProiIPR001955. Pancreatic_hormone-like.
    IPR020392. Pancreatic_hormone-like_CS.
    [Graphical view]
    PfamiPF00159. Hormone_3. 1 hit.
    [Graphical view]
    PRINTSiPR00278. PANCHORMONE.
    ProDomiPD001267. Pancreatic_hormone-like. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00309. PAH. 1 hit.
    [Graphical view]
    PROSITEiPS00265. PANCREATIC_HORMONE_1. 1 hit.
    PS50276. PANCREATIC_HORMONE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P06304-1 [UniParc]FASTAAdd to Basket

    « Hide

    GPSQPTYPGN DAPVEDLRFY YDNLQQYRLN VFRHRY                  36
    Length:36
    Mass (Da):4,391
    Last modified:April 1, 1988 - v1
    Checksum:i32141F4536F427EF
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti30 – 301N → V.

    Sequence databases

    PIRiA01576. PCGS.

    Cross-referencesi

    Sequence databases

    PIRi A01576. PCGS.

    3D structure databases

    ProteinModelPortali P06304.
    SMRi P06304. Positions 1-36.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG096194.

    Family and domain databases

    InterProi IPR001955. Pancreatic_hormone-like.
    IPR020392. Pancreatic_hormone-like_CS.
    [Graphical view ]
    Pfami PF00159. Hormone_3. 1 hit.
    [Graphical view ]
    PRINTSi PR00278. PANCHORMONE.
    ProDomi PD001267. Pancreatic_hormone-like. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00309. PAH. 1 hit.
    [Graphical view ]
    PROSITEi PS00265. PANCREATIC_HORMONE_1. 1 hit.
    PS50276. PANCREATIC_HORMONE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and sequence determination of goose pancreatic polypeptide."
      Xu Y., Lin N., Zhang Y.S.
      Sci. Sin., Ser. B Chem. Biol. Agric. Med. Earth Sci. 27:590-592(1984) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
    2. Cited for: PROTEIN SEQUENCE.

    Entry informationi

    Entry nameiPAHO_ANSAN
    AccessioniPrimary (citable) accession number: P06304
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 1, 1988
    Last sequence update: April 1, 1988
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3