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Protein

NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic

Gene

ndhF

Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).By similarity

Catalytic activityi

NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTransport
LigandNAD, NADP, Plastoquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic (EC:1.6.5.-)
Alternative name(s):
NAD(P)H dehydrogenase subunit 5
NADH-plastoquinone oxidoreductase subunit 5
Gene namesi
Name:ndhF
Synonyms:ndh5
Encoded oniPlastid; Chloroplast
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei125 – 145HelicalSequence analysisAdd BLAST21
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21
Transmembranei219 – 239HelicalSequence analysisAdd BLAST21
Transmembranei258 – 278HelicalSequence analysisAdd BLAST21
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei327 – 347HelicalSequence analysisAdd BLAST21
Transmembranei354 – 374HelicalSequence analysisAdd BLAST21
Transmembranei396 – 416HelicalSequence analysisAdd BLAST21
Transmembranei425 – 445HelicalSequence analysisAdd BLAST21
Transmembranei543 – 563HelicalSequence analysisAdd BLAST21
Transmembranei602 – 622HelicalSequence analysisAdd BLAST21
Transmembranei717 – 737HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001182061 – 740NAD(P)H-quinone oxidoreductase subunit 5, chloroplasticAdd BLAST740

Keywords - PTMi

Quinone

Interactioni

Subunit structurei

NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I subunit 5 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

InterProiView protein in InterPro
IPR002128. NADH_UbQ_OxRdtase_chlpt_su5_C.
IPR003945. NADHpl_OxRdtase_5.
IPR018393. NADHpl_OxRdtase_5_subgr.
IPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
PfamiView protein in Pfam
PF01010. Proton_antipo_C. 1 hit.
PF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
PRINTSiPR01435. NPOXDRDTASE5.
TIGRFAMsiTIGR01974. NDH_I_L. 1 hit.

Sequencei

Sequence statusi: Complete.

P06265-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQTYEYAWI IPFIPLPVPM LIGAGLFLFP TATKSFRRMW AFQSVLLLSI
60 70 80 90 100
VMVFSIYLSI QQINSSSFYQ YVWSWIINND FSLDFGYLID PLTSIMSILI
110 120 130 140 150
TTVGIMVLIY SDNYMAHDQG YLRFFAYMSF FSTSMLGLVT SSNLIQIYIF
160 170 180 190 200
WELVGLCSYL LIGFWFTRPV AANACQKAFV TNRVGDFGLL LGILGFYWIT
210 220 230 240 250
GSFEFRDLFE IFNNLIYNNE VDFLFVTLCA VLLFAGAVAK SAQFPLHVWL
260 270 280 290 300
PDAMEGPTPI SALIHAATMV AAGIFLVARL LPLFRVIPYI MYLISVIGII
310 320 330 340 350
TVLLGATLAL AQKDIKRGLA YSTMSQLGYM MLALGMGSYR SALFHLITHA
360 370 380 390 400
YSKALLFLGS GSIIHSMETI VGYSPAKSQN MGLMGGLRKH VPISKITFLL
410 420 430 440 450
GTLSLCGIPP LACFWSKDEI LNDSWLYSPI FAIIAWATAG LTAFYMFRIY
460 470 480 490 500
LLTFEGHLNA HFPNYGGKQK TPFYSISLWG KNGVKKNSCL LTMNNNESTY
510 520 530 540 550
FFAKTKYPID KNGRKMTRPF MTIAHFEHKA VYSYPYESDN TMLFPIFVLG
560 570 580 590 600
LFTLFVGSIG IPFNQEGGNL DILSKWLAPS INLLHQKSNN SMDWNEFLKD
610 620 630 640 650
AVLSVSIAYF GIFIASFLYK PIYSSLKNFE LINSFVKKGP KRILWDKIIN
660 670 680 690 700
GIYDWSYNRA YIDAFYTRFL VGGIRGLAEF THFFDRRVID GMTNGVGVIS
710 720 730 740
FIVGEGIKYI GGGRISSYLF LYLAYVSIFL LVYYLLFSTL
Length:740
Mass (Da):83,717
Last modified:June 1, 1994 - v2
Checksum:iD69519BAF8BF0B54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L14953 Genomic DNA. Translation: AAA84685.1.
Z00044 Genomic DNA. Translation: CAA77430.1.
PIRiS37352. DENTN5.
RefSeqiNP_054554.1. NC_001879.2.

Genome annotation databases

GeneIDi800484.
KEGGinta:800484.

Similar proteinsi

Entry informationi

Entry nameiNU5C_TOBAC
AccessioniPrimary (citable) accession number: P06265
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: June 1, 1994
Last modified: May 10, 2017
This is version 89 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families