Reviewed, UniProtKB/Swiss-Prot P06188 (ARAB_SALTY)

Names and origin

Protein names

Recommended name:
    Ribulokinase
    EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	STM0103

Organism

Salmonella typhimurium [Complete proteome] [HAMAP]

Taxonomic identifier

90371 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	569 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacteria route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 569	568	Ribulokinase HAMAP MF_00520		PRO_0000198364

Sequences

	Sequence		Length	Mass (Da)
	P06188-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: AD510072F244EC34	FASTA	569	61,752
	10 20 30 40 50 60 MAIAIGLDFG SDSVRALAVD CATGDEIATS VEWYPRWQEG RYCDGPNNQF RHHPRDYMES 70 80 90 100 110 120 MEAALKAVLA QLSAAQRANV VGIGVDSTGS TPAPIDADGN VLALRPEFAE NPNAMFVLWK 130 140 150 160 170 180 DHTAVEEADE ITRLCHKPGK VDYSRYIGGI YSSEWFWAKI LHVTRQDSAV AQAAVSWIEL 190 200 210 220 230 240 CDWVPALLSG TTRPQDIRRG RCSAGHKTLW HESWGGLPPA SFFDELDPCI NRHLRYPLFS 250 260 270 280 290 300 ETFTADLPVG TLCAEWAQRL DLPESVVISG GAFDCHMGAV GAGAQPNTLV KVIGTSTCDI 310 320 330 340 350 360 LIADKQSVGD RAVKGICGQV DGSVVPNFIG LEAGQSAFGD IYAWFSRVLS WPLEQLAAQH 370 380 390 400 410 420 PELKPQINAS QKQLLPALTD AWAKNPSLDH LPVVLDWFNG RRTPNANQRL KGVITDLNLA 430 440 450 460 470 480 TDAPALFGGL VASTAFGARA IQECFTDQGI AVNNVMALGG IARKNQVIMQ VCCDVLNRPL 490 500 510 520 530 540 QIVASDQCCA LGAAIFAAVA AKVHADIPAA QQSMASAVER TLRPHPEQAQ RFEQLYRRYQ 550 560 QWALSAEQHY LPTAAPAPTT PANQAILTH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The araBAD operon of Salmonella typhimurium LT2. I. Nucleotide sequence of araB and primary structure of its product, ribulokinase." Lin H.-C., Lei S.-P., Wilcox G. Gene 34:111-122(1985) [PubMed: 2989100] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K. Nature 413:852-856(2001) [PubMed: 11677609] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M11047 Genomic DNA. Translation: AAA27023.1. AE008698 Genomic DNA. Translation: AAL19067.1.
PIR	A24984.
RefSeq	NP_459108.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1251621.
GenomeReviews	Gene locus STM0103 in contig AE006468_GR.
KEGG	stm:STM0103.
NMPDR	fig|99287.1.peg.101.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P06188.
OMA	P06188. NGRRTPD.
Enzyme and pathway databases
BioCyc	STYP99287:STM0103-MON.
BRENDA	2.7.1.16. 2.
Family and domain databases
HAMAP	MF_00520. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01234. L-ribulokinase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAB_SALTY

Accession

Primary (citable) accession number: P06188

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 1, 1988
Last sequence update:	January 23, 2007
Last modified:	June 16, 2009
This is version 61 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)