Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c oxidase subunit 3

Gene

ctaE

Organism
Paracoccus denitrificans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Oxidase aa(3) subunit 3
Gene namesi
Name:ctaE
Synonyms:coiII
OrganismiParacoccus denitrificans
Taxonomic identifieri266 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini2 – 15CytoplasmicAdd BLAST14
Transmembranei16 – 36HelicalAdd BLAST21
Topological domaini37 – 48PeriplasmicAdd BLAST12
Transmembranei49 – 77HelicalAdd BLAST29
Topological domaini78 – 79Cytoplasmic2
Transmembranei80 – 115HelicalAdd BLAST36
Topological domaini116 – 139PeriplasmicAdd BLAST24
Transmembranei140 – 166HelicalAdd BLAST27
Topological domaini167 – 168Cytoplasmic2
Transmembranei169 – 197HelicalAdd BLAST29
Topological domaini198 – 203Periplasmic6
Transmembranei204 – 237HelicalAdd BLAST34
Topological domaini238 – 244Cytoplasmic7
Transmembranei245 – 274HelicalAdd BLAST30

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001838862 – 274Cytochrome c oxidase subunit 3Add BLAST273

Interactioni

Protein-protein interaction databases

STRINGi318586.Pden_4317.

Structurei

Secondary structure

1274
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi17 – 36Combined sources20
Beta strandi42 – 44Combined sources3
Turni51 – 53Combined sources3
Helixi54 – 75Combined sources22
Helixi81 – 114Combined sources34
Turni119 – 123Combined sources5
Turni138 – 140Combined sources3
Helixi141 – 165Combined sources25
Helixi169 – 175Combined sources7
Helixi177 – 180Combined sources4
Helixi182 – 193Combined sources12
Helixi194 – 196Combined sources3
Beta strandi201 – 203Combined sources3
Helixi205 – 235Combined sources31
Turni236 – 238Combined sources3
Helixi246 – 267Combined sources22
Helixi268 – 272Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QLEX-ray3.00C2-274[»]
ProteinModelPortaliP06030.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP06030.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QS1. Bacteria.
COG1845. LUCA.

Family and domain databases

CDDicd01665. Cyt_c_Oxidase_III. 1 hit.
Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR033945. Cyt_c_oxase_su3_dom.
IPR000298. Cyt_c_oxidase-like_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P06030-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHVKNHDYQ ILPPSIWPFF GAIGAFVMLT GAVAWMKGIT FFGLPVEGPW
60 70 80 90 100
MFLIGLVGVL YVMFGWWADV VNEGETGEHT PVVRIGLQYG FILFIMSEVM
110 120 130 140 150
FFVAWFWAFI KNALYPMGPD SPIKDGVWPP EGIVTFDPWH LPLINTLILL
160 170 180 190 200
LSGVAVTWAH HAFVLEGDRK TTINGLIVAV ILGVCFTGLQ AYEYSHAAFG
210 220 230 240 250
LADTVYAGAF YMATGFHGAH VIIGTIFLFV CLIRLLKGQM TQKQHVGFEA
260 270
AAWYWHFVDV VWLFLFVVIY IWGR
Length:274
Mass (Da):30,786
Last modified:January 23, 2007 - v3
Checksum:i082F95AF9AD4A27B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04406 Genomic DNA. Translation: CAA27995.1.
X05828 Genomic DNA. Translation: CAA29272.1.
PIRiS03807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04406 Genomic DNA. Translation: CAA27995.1.
X05828 Genomic DNA. Translation: CAA29272.1.
PIRiS03807.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QLEX-ray3.00C2-274[»]
ProteinModelPortaliP06030.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi318586.Pden_4317.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4107QS1. Bacteria.
COG1845. LUCA.

Miscellaneous databases

EvolutionaryTraceiP06030.

Family and domain databases

CDDicd01665. Cyt_c_Oxidase_III. 1 hit.
Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR033945. Cyt_c_oxase_su3_dom.
IPR000298. Cyt_c_oxidase-like_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCOX3_PARDE
AccessioniPrimary (citable) accession number: P06030
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: January 23, 2007
Last modified: November 30, 2016
This is version 105 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.