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P06030

- COX3_PARDE

UniProt

P06030 - COX3_PARDE

Protein

Cytochrome c oxidase subunit 3

Gene

ctaE

Organism
Paracoccus denitrificans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciRETL1328306-WGS:GSTH-972-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 3
    Cytochrome c oxidase polypeptide III
    Oxidase aa(3) subunit 3
    Gene namesi
    Name:ctaE
    Synonyms:coiII
    OrganismiParacoccus denitrificans
    Taxonomic identifieri266 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 274273Cytochrome c oxidase subunit 3PRO_0000183886Add
    BLAST

    Structurei

    Secondary structure

    1
    274
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi17 – 3620
    Beta strandi42 – 443
    Turni51 – 533
    Helixi54 – 7522
    Helixi81 – 11434
    Turni119 – 1235
    Turni138 – 1403
    Helixi141 – 16525
    Helixi169 – 1757
    Helixi177 – 1804
    Helixi182 – 19312
    Helixi194 – 1963
    Beta strandi201 – 2033
    Helixi205 – 23531
    Turni236 – 2383
    Helixi246 – 26722
    Helixi268 – 2725

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1QLEX-ray3.00C2-274[»]
    ProteinModelPortaliP06030.
    SMRiP06030. Positions 2-274.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP06030.

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini2 – 1514CytoplasmicAdd
    BLAST
    Topological domaini37 – 4812PeriplasmicAdd
    BLAST
    Topological domaini78 – 792Cytoplasmic
    Topological domaini116 – 13924PeriplasmicAdd
    BLAST
    Topological domaini167 – 1682Cytoplasmic
    Topological domaini198 – 2036Periplasmic
    Topological domaini238 – 2447Cytoplasmic

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei16 – 3621HelicalAdd
    BLAST
    Transmembranei49 – 7729HelicalAdd
    BLAST
    Transmembranei80 – 11536HelicalAdd
    BLAST
    Transmembranei140 – 16627HelicalAdd
    BLAST
    Transmembranei169 – 19729HelicalAdd
    BLAST
    Transmembranei204 – 23734HelicalAdd
    BLAST
    Transmembranei245 – 27430HelicalAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P06030-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAHVKNHDYQ ILPPSIWPFF GAIGAFVMLT GAVAWMKGIT FFGLPVEGPW    50
    MFLIGLVGVL YVMFGWWADV VNEGETGEHT PVVRIGLQYG FILFIMSEVM 100
    FFVAWFWAFI KNALYPMGPD SPIKDGVWPP EGIVTFDPWH LPLINTLILL 150
    LSGVAVTWAH HAFVLEGDRK TTINGLIVAV ILGVCFTGLQ AYEYSHAAFG 200
    LADTVYAGAF YMATGFHGAH VIIGTIFLFV CLIRLLKGQM TQKQHVGFEA 250
    AAWYWHFVDV VWLFLFVVIY IWGR 274
    Length:274
    Mass (Da):30,786
    Last modified:January 23, 2007 - v3
    Checksum:i082F95AF9AD4A27B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X04406 Genomic DNA. Translation: CAA27995.1.
    X05828 Genomic DNA. Translation: CAA29272.1.
    PIRiS03807.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X04406 Genomic DNA. Translation: CAA27995.1 .
    X05828 Genomic DNA. Translation: CAA29272.1 .
    PIRi S03807.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1QLE X-ray 3.00 C 2-274 [» ]
    ProteinModelPortali P06030.
    SMRi P06030. Positions 2-274.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    BioCyci RETL1328306-WGS:GSTH-972-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P06030.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and analysis of the genes for cytochrome c oxidase in Paracoccus denitrificans."
      Raitio M., Jalli T., Saraste M.
      EMBO J. 6:2825-2833(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: S1657.
    2. "A gene in Paracoccus for subunit III of cytochrome oxidase."
      Saraste M., Raitio M., Jalli T., Peraemaa A.
      FEBS Lett. 206:154-156(1986) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-144.
      Strain: S1657.
    3. "The Paracoccus denitrificans cytochrome aa3 has a third subunit."
      Haltia T., Puustinen A., Finel M.
      Eur. J. Biochem. 172:543-546(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-16.
    4. "Structure at 2.8-A resolution of cytochrome c oxidase from Paracoccus denitrificans."
      Iwata S., Ostermeier C., Ludwig B., Michel H.
      Nature 376:660-669(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS).

    Entry informationi

    Entry nameiCOX3_PARDE
    AccessioniPrimary (citable) accession number: P06030
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 13, 1987
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 95 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3