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Protein

40S ribosomal protein S6-A

Gene

rps601

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

There are two genes for S6 in S.pombe.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SPO-72702. Ribosomal scanning and start codon recognition.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S6-A
Gene namesi
Name:rps601
Synonyms:rps6, rps6a
ORF Names:SPAC13G6.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC13G6.07c.
PomBaseiSPAC13G6.07c. rps601.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • cytosolic small ribosomal subunit Source: PomBase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001373391 – 23940S ribosomal protein S6-AAdd BLAST239

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei235PhosphoserineSequence analysis1
Modified residuei236PhosphoserineSequence analysis1

Post-translational modificationi

Phosphorylated.

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP05752.
PRIDEiP05752.

Interactioni

Protein-protein interaction databases

BioGridi279315. 3 interactors.
IntActiP05752. 2 interactors.
MINTiMINT-4686842.
STRINGi4896.SPAC13G6.07c.1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000190952.
InParanoidiP05752.
KOiK02991.
OMAiRVLTHGC.
OrthoDBiEOG092C4QCP.
PhylomeDBiP05752.

Family and domain databases

InterProiView protein in InterPro
IPR014401. Ribosomal_S6_euk.
IPR001377. Ribosomal_S6e.
IPR018282. Ribosomal_S6e_CS.
PANTHERiPTHR11502. PTHR11502. 1 hit.
PfamiView protein in Pfam
PF01092. Ribosomal_S6e. 1 hit.
PIRSFiPIRSF002129. Ribosom_S6_euk. 1 hit.
SMARTiView protein in SMART
SM01405. Ribosomal_S6e. 1 hit.
PROSITEiView protein in PROSITE
PS00578. RIBOSOMAL_S6E. 1 hit.

Sequencei

Sequence statusi: Complete.

P05752-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNISYPAN GTQKLIEIDD DRRLRVFMEK RMGQEVPGDS VGPEFAGYVF
60 70 80 90 100
KITGGNDKQG FPMFQGVLLP HRVRLLLRAG HPCYRPRRDG ERKRKSVRGC
110 120 130 140 150
IVGQDLAVLA LAIIKQGEQD IPGLTDVTVP KRLGPKRASK IRRFFNLSKE
160 170 180 190 200
DDVRQFVIRR EVVPKKEGKK PYTKAPKIQR LVTPRTLQHK RHRFALKRRQ
210 220 230
AEKNREEAAE FAQLMAKRVA EAKQKREVVK ARRASSLKK
Length:239
Mass (Da):27,499
Last modified:November 1, 1990 - v2
Checksum:i3C65751DFA2D9E16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M36382 Genomic DNA. Translation: AAA35338.1.
CU329670 Genomic DNA. Translation: CAA91100.1.
PIRiS06463. R3ZP6E.
RefSeqiNP_592833.1. NM_001018234.2.

Genome annotation databases

EnsemblFungiiSPAC13G6.07c.1; SPAC13G6.07c.1:pep; SPAC13G6.07c.
GeneIDi2542870.
KEGGispo:SPAC13G6.07c.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRS6A_SCHPO
AccessioniPrimary (citable) accession number: P05752
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: November 1, 1990
Last modified: July 5, 2017
This is version 133 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families