60S ribosomal protein L36-A - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

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P05745 (RL36A_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 107. History...

Clusters with 100%, 90%, 50% identity |

Documents (5) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
60S ribosomal protein L36-A

Alternative name(s):
L39
YL39

Gene names

Name:	RPL36A
Synonyms:	RPL39A
Ordered Locus Names:	YMR194W
ORF Names:	YM9646.06

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length	100 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.3
Subcellular location	Cytoplasm Ref.5.
Post-translational modification	N-terminally acetylated by acetyltransferase NatA.
Miscellaneous	Present with 31600 molecules/cell in log phase SD medium. There are 2 genes for L36 in yeast.
Sequence similarities	Belongs to the ribosomal protein L36e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Acetylation Phosphoprotein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cytoplasmic translation Inferred from direct assay PubMed 18782943. Source: SGD
Cellular_component	cytosolic large ribosomal subunit Inferred from direct assay PubMed 18782943. Source: SGD
Molecular_function	RNA binding Inferred from direct assay PubMed 6337137. Source: SGD structural constituent of ribosome Inferred from direct assay PubMed 18782943. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

Removed Ref.4

Chain

2 – 100

60S ribosomal protein L36-A

PRO_0000195020

Amino acid modifications

Modified residue

N-acetylthreonine Ref.4

Modified residue

Phosphoserine Ref.9

Modified residue

Phosphoserine Ref.7 Ref.8

Modified residue

Phosphoserine Ref.9

Sequences

Sequence

Length

Mass (Da)

Tools

P05745 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 9CAA7BFFF33D0C25
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FASTA

100

11,124

        10         20         30         40         50         60 
MTVKTGIAIG LNKGKKVTSM TPAPKISYKK GAASNRTKFV RSLVREIAGL SPYERRLIDL 

        70         80         90        100 
IRNSGEKRAR KVAKKRLGSF TRAKAKVEEM NNIIAASRRH

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. Barrell B.G. Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[4]	"The action of N-terminal acetyltransferases on yeast ribosomal proteins." Arnold R.J., Polevoda B., Reilly J.P., Sherman F. J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract] Cited for: CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT THR-2 BY NATA.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]	"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway." Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N. Mol. Cell. Proteomics 4:310-327(2005) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-79, MASS SPECTROMETRY. Strain: YAL6B.
[8]	"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry." Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F. Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-79, MASS SPECTROMETRY.
[9]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19 AND SER-97, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

Z47815 Genomic DNA. Translation: CAA87815.1.
BK006946 Genomic DNA. Translation: DAA10092.1.

PIR

S50922. S11263.

RefSeq

NP_013920.1. NM_001182701.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IZS	electron microscopy	-	k	1-100	[»]
3U5E	X-ray	3.00	i	1-100	[»]
3U5I	X-ray	3.00	i	1-100	[»]
4B6A	electron microscopy	8.10	i	1-100	[»]

ProteinModelPortal

P05745.

SMR

P05745. Positions 2-100.

ModBase

Search...

Protein-protein interaction databases

IntAct

P05745. 12 interactions.

STRING

4932.YMR194W.

Proteomic databases

PaxDb

P05745.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblFungi

YMR194W; YMR194W; YMR194W.

GeneID

855232.

KEGG

sce:YMR194W.

Organism-specific databases

SGD

S000004807. RPL36A.

Phylogenomic databases

eggNOG

COG5051.

GeneTree

ENSGT00390000011943.

HOGENOM

HOG000155312.

K02920.

OMA

AGSAPYE.

OrthoDB

EOG43FM69.

Gene expression databases

Genevestigator

P05745.

GermOnline

YMR194W. Saccharomyces cerevisiae.

Family and domain databases

InterPro

IPR000509. Ribosomal_L36e.
[Graphical view]

PANTHER

PTHR10114. PTHR10114. 1 hit.

Pfam

PF01158. Ribosomal_L36e. 1 hit.
[Graphical view]

PROSITE

PS01190. RIBOSOMAL_L36E. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

NextBio

978774.

Entry information

Entry name

RL36A_YEAST

Accession

Primary (citable) accession number: P05745
Secondary accession number(s): D6W018

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1988
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 107 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program