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P05745 (RL36A_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 114. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L36-A
Alternative name(s):
L39
YL39
Gene names
Name:RPL36A
Synonyms:RPL39A
Ordered Locus Names:YMR194W
ORF Names:YM9646.06
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length100 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.3

Subcellular location

Cytoplasm Ref.5.

Post-translational modification

N-terminally acetylated by acetyltransferase NatA. Ref.4

Miscellaneous

Present with 31600 molecules/cell in log phase SD medium.

There are 2 genes for L36 in yeast.

Sequence similarities

Belongs to the ribosomal protein L36e family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.4
Chain2 – 1009960S ribosomal protein L36-A
PRO_0000195020

Amino acid modifications

Modified residue21N-acetylthreonine Ref.4

Sequences

Sequence LengthMass (Da)Tools
P05745 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 9CAA7BFFF33D0C25

FASTA10011,124
        10         20         30         40         50         60 
MTVKTGIAIG LNKGKKVTSM TPAPKISYKK GAASNRTKFV RSLVREIAGL SPYERRLIDL 

        70         80         90        100 
IRNSGEKRAR KVAKKRLGSF TRAKAKVEEM NNIIAASRRH 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII."
Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. expand/collapse author list , Skelton J., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
Planta R.J., Mager W.H.
Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE, SUBUNIT.
[4]"The action of N-terminal acetyltransferases on yeast ribosomal proteins."
Arnold R.J., Polevoda B., Reilly J.P., Sherman F.
J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT THR-2 BY NATA.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]"Crystal structure of the eukaryotic ribosome."
Ben-Shem A., Jenner L., Yusupova G., Yusupov M.
Science 330:1203-1209(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
[8]"The structure of the eukaryotic ribosome at 3.0 A resolution."
Ben-Shem A., Garreau de Loubresse N., Melnikov S., Jenner L., Yusupova G., Yusupov M.
Science 334:1524-1529(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z47815 Genomic DNA. Translation: CAA87815.1.
BK006946 Genomic DNA. Translation: DAA10092.1.
PIRS50922. S11263.
RefSeqNP_013920.1. NM_001182701.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3IZSelectron microscopy-k1-100[»]
3J65electron microscopy8.70g1-100[»]
3U5EX-ray3.00i1-100[»]
3U5IX-ray3.00i1-100[»]
4B6Aelectron microscopy8.10i1-100[»]
4BYNelectron microscopy4.30i2-100[»]
4BYUelectron microscopy6.60i2-100[»]
ProteinModelPortalP05745.
SMRP05745. Positions 2-100.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35372. 114 interactions.
IntActP05745. 13 interactions.
MINTMINT-1898050.
STRING4932.YMR194W.

Proteomic databases

MaxQBP05745.
PaxDbP05745.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYMR194W; YMR194W; YMR194W.
GeneID855232.
KEGGsce:YMR194W.

Organism-specific databases

SGDS000004807. RPL36A.

Phylogenomic databases

eggNOGCOG5051.
GeneTreeENSGT00390000011943.
HOGENOMHOG000155312.
KOK02920.
OMADIPINES.
OrthoDBEOG712V86.

Enzyme and pathway databases

BioCycYEAST:G3O-32881-MONOMER.

Gene expression databases

GenevestigatorP05745.

Family and domain databases

InterProIPR000509. Ribosomal_L36e.
[Graphical view]
PANTHERPTHR10114. PTHR10114. 1 hit.
PfamPF01158. Ribosomal_L36e. 1 hit.
[Graphical view]
PROSITEPS01190. RIBOSOMAL_L36E. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio978774.

Entry information

Entry nameRL36A_YEAST
AccessionPrimary (citable) accession number: P05745
Secondary accession number(s): D6W018
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 114 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references