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P05743 (RL26A_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 128. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L26-A
Alternative name(s):
L33
YL33
Gene names
Name:RPL26A
Synonyms:RPL26, RPL33A
Ordered Locus Names:YLR344W
ORF Names:L8300.4
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length127 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.4

Subcellular location

Cytoplasm Ref.5.

Miscellaneous

There are 2 genes for L26 in yeast.

Sequence similarities

Belongs to the ribosomal protein L24P family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.3
Chain2 – 12712660S ribosomal protein L26-A
PRO_0000130801

Sequences

Sequence LengthMass (Da)Tools
P05743 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 3888654AC1587E8E

FASTA12714,234
        10         20         30         40         50         60 
MAKQSLDVSS DRRKARKAYF TAPSSQRRVL LSAPLSKELR AQYGIKALPI RRDDEVLVVR 

        70         80         90        100        110        120 
GSKKGQEGKI SSVYRLKFAV QVDKVTKEKV NGASVPINLH PSKLVITKLH LDKDRKALIQ 


RKGGKLE 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. expand/collapse author list , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes."
Otaka E., Higo K., Itoh T.
Mol. Gen. Genet. 195:544-546(1984) [PubMed] [Europe PMC] [Abstract]
Cited for: PARTIAL PROTEIN SEQUENCE OF 2-41, CLEAVAGE OF INITIATOR METHIONINE.
[4]"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
Planta R.J., Mager W.H.
Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE, SUBUNIT.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-ribosome and subunit-subunit interactions."
Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G., Frank J.
Cell 107:373-386(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: 3D-STRUCTURE MODELING OF 9-123, ELECTRON MICROSCOPY.
[7]"Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation."
Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R., Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J.
EMBO J. 23:1008-1019(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: 3D-STRUCTURE MODELING, ELECTRON MICROSCOPY.
[8]"Crystal structure of the eukaryotic ribosome."
Ben-Shem A., Jenner L., Yusupova G., Yusupov M.
Science 330:1203-1209(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
[9]"The structure of the eukaryotic ribosome at 3.0 A resolution."
Ben-Shem A., Garreau de Loubresse N., Melnikov S., Jenner L., Yusupova G., Yusupov M.
Science 334:1524-1529(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U19028 Genomic DNA. Translation: AAB67254.1.
BK006945 Genomic DNA. Translation: DAA09649.1.
PIRS51347.
RefSeqNP_013448.1. NM_001182233.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1K5Ymodel-U9-123[»]
1S1Ielectron microscopy11.70U2-127[»]
2WW9electron microscopy8.60L1-127[»]
2WWAelectron microscopy8.90L1-127[»]
3IZSelectron microscopy-Y1-123[»]
3O58X-ray4.00X1-127[»]
3O5HX-ray4.00X1-127[»]
3U5EX-ray3.00Y1-127[»]
3U5IX-ray3.00Y1-127[»]
4B6Aelectron microscopy8.10Y1-127[»]
4BYNelectron microscopy4.30Y2-127[»]
4BYUelectron microscopy6.60Y2-127[»]
ProteinModelPortalP05743.
SMRP05743. Positions 2-127.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31607. 37 interactions.
DIPDIP-5584N.
IntActP05743. 7 interactions.
MINTMINT-8285368.
STRING4932.YLR344W.

Proteomic databases

PeptideAtlasP05743.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYLR344W; YLR344W; YLR344W.
GeneID851058.
KEGGsce:YLR344W.

Organism-specific databases

SGDS000004336. RPL26A.

Phylogenomic databases

GeneTreeENSGT00390000014165.
HOGENOMHOG000216571.
KOK02898.
OMAVRIMRGD.
OrthoDBEOG747PX1.

Enzyme and pathway databases

BioCycYEAST:G3O-32420-MONOMER.

Gene expression databases

GenevestigatorP05743.

Family and domain databases

Gene3D2.30.30.30. 1 hit.
InterProIPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR005825. Ribosomal_L24/26_CS.
IPR005756. Ribosomal_L26/L24P_euk/arc.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERPTHR11143. PTHR11143. 1 hit.
PfamPF00467. KOW. 1 hit.
[Graphical view]
SMARTSM00739. KOW. 1 hit.
[Graphical view]
SUPFAMSSF50104. SSF50104. 1 hit.
TIGRFAMsTIGR01080. rplX_A_E. 1 hit.
PROSITEPS01108. RIBOSOMAL_L24. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP05743.
NextBio967681.

Entry information

Entry nameRL26A_YEAST
AccessionPrimary (citable) accession number: P05743
Secondary accession number(s): D6VYY3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 128 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XII

Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references