60S ribosomal protein L26-A - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

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P05743 (RL26A_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 121. History...

Clusters with 100%, 90%, 50% identity |

Documents (5) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
60S ribosomal protein L26-A

Alternative name(s):
L33
YL33

Gene names

Name:	RPL26A
Synonyms:	RPL26, RPL33A
Ordered Locus Names:	YLR344W
ORF Names:	L8300.4

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length	127 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.4
Subcellular location	Cytoplasm Ref.5.
Miscellaneous	There are 2 genes for L26 in yeast.
Sequence similarities	Belongs to the ribosomal protein L24P family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	cytoplasmic translation Inferred from direct assay PubMed 18782943. Source: SGD
Cellular_component	cytosolic large ribosomal subunit Inferred from direct assay PubMed 18782943 PubMed 9672752. Source: SGD
Molecular_function	RNA binding Inferred from direct assay PubMed 6337137. Source: SGD structural constituent of ribosome Inferred from direct assay PubMed 18782943. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

Removed Ref.3

Chain

2 – 127

126

60S ribosomal protein L26-A

PRO_0000130801

Sequences

Sequence

Length

Mass (Da)

Tools

P05743 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 3888654AC1587E8E
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FASTA

127

14,234

        10         20         30         40         50         60 
MAKQSLDVSS DRRKARKAYF TAPSSQRRVL LSAPLSKELR AQYGIKALPI RRDDEVLVVR 

        70         80         90        100        110        120 
GSKKGQEGKI SSVYRLKFAV QVDKVTKEKV NGASVPINLH PSKLVITKLH LDKDRKALIQ 


RKGGKLE

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. Hoheisel J.D. Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes." Otaka E., Higo K., Itoh T. Mol. Gen. Genet. 195:544-546(1984) Cited for: PROTEIN SEQUENCE OF 2-41.
[4]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-ribosome and subunit-subunit interactions." Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G., Frank J. Cell 107:373-386(2001) [PubMed] [Europe PMC] [Abstract] Cited for: 3D-STRUCTURE MODELING OF 9-123, ELECTRON MICROSCOPY.
[7]	"Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation." Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R., Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J. EMBO J. 23:1008-1019(2004) [PubMed] [Europe PMC] [Abstract] Cited for: 3D-STRUCTURE MODELING, ELECTRON MICROSCOPY.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U19028 Genomic DNA. Translation: AAB67254.1.
BK006945 Genomic DNA. Translation: DAA09649.1.

PIR

S51347.

RefSeq

NP_013448.1. NM_001182233.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1K5Y	model	-	U	9-123	[»]
1S1I	electron microscopy	11.70	U	2-127	[»]
2WW9	electron microscopy	8.60	L	1-127	[»]
2WWA	electron microscopy	8.90	L	1-127	[»]
3IZS	electron microscopy	-	Y	1-123	[»]
3O58	X-ray	4.00	X	1-127	[»]
3O5H	X-ray	4.00	X	1-127	[»]
3U5E	X-ray	3.00	Y	1-127	[»]
3U5I	X-ray	3.00	Y	1-127	[»]
4B6A	electron microscopy	8.10	Y	1-127	[»]

ProteinModelPortal

P05743.

SMR

P05743. Positions 2-127.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-5584N.

IntAct

P05743. 4 interactions.

MINT

MINT-497199.

STRING

4932.YLR344W.

Proteomic databases

PeptideAtlas

P05743.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblFungi

YLR344W; YLR344W; YLR344W.

GeneID

851058.

KEGG

sce:YLR344W.

Organism-specific databases

SGD

S000004336. RPL26A.

Phylogenomic databases

GeneTree

ENSGT00390000014165.

HOGENOM

HOG000216571.

K02898.

OMA

VRIMRGD.

OrthoDB

EOG4KM2CK.

Gene expression databases

Genevestigator

P05743.

GermOnline

YLR344W. Saccharomyces cerevisiae.

Family and domain databases

Gene3D

2.30.30.30. 1 hit.

InterPro

IPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR005825. Ribosomal_L24/26_CS.
IPR005756. Ribosomal_L26/L24P_euk/arc.
IPR008991. Translation_prot_SH3-like.
[Graphical view]

PANTHER

PTHR11143. PTHR11143. 1 hit.

Pfam

PF00467. KOW. 1 hit.
[Graphical view]

SMART

SM00739. KOW. 1 hit.
[Graphical view]

SUPFAM

SSF50104. Transl_SH3_like. 1 hit.

TIGRFAMs

TIGR01080. rplX_A_E. 1 hit.

PROSITE

PS01108. RIBOSOMAL_L24. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

P05743.

NextBio

967681.

Entry information

Entry name

RL26A_YEAST

Accession

Primary (citable) accession number: P05743
Secondary accession number(s): D6VYY3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1988
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 121 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program