Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P05743

- RL26A_YEAST

UniProt

P05743 - RL26A_YEAST

Protein

60S ribosomal protein L26-A

Gene

RPL26A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. RNA binding Source: SGD
    2. structural constituent of ribosome Source: SGD

    GO - Biological processi

    1. cytoplasmic translation Source: SGD

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32420-MONOMER.
    ReactomeiREACT_188965. SRP-dependent cotranslational protein targeting to membrane.
    REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_217188. Formation of a pool of free 40S subunits.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    60S ribosomal protein L26-A
    Alternative name(s):
    L33
    YL33
    Gene namesi
    Name:RPL26A
    Synonyms:RPL26, RPL33A
    Ordered Locus Names:YLR344W
    ORF Names:L8300.4
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XII

    Organism-specific databases

    SGDiS000004336. RPL26A.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytosolic large ribosomal subunit Source: SGD

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 12712660S ribosomal protein L26-APRO_0000130801Add
    BLAST

    Proteomic databases

    PeptideAtlasiP05743.

    Expressioni

    Gene expression databases

    GenevestigatoriP05743.

    Interactioni

    Subunit structurei

    Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

    Protein-protein interaction databases

    BioGridi31607. 37 interactions.
    DIPiDIP-5584N.
    IntActiP05743. 7 interactions.
    MINTiMINT-8285368.
    STRINGi4932.YLR344W.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1K5Ymodel-U9-123[»]
    1S1Ielectron microscopy11.70U2-127[»]
    1VW8electron microscopy6.10Z1-127[»]
    1VWUelectron microscopy6.10Z1-127[»]
    2WW9electron microscopy8.60L1-127[»]
    2WWAelectron microscopy8.90L1-127[»]
    2WWBelectron microscopy6.48L1-127[»]
    3IZSelectron microscopy-Y1-123[»]
    3J65electron microscopy8.70X1-127[»]
    3O58X-ray4.00X1-127[»]
    3O5HX-ray4.00X1-127[»]
    3U5EX-ray3.00Y1-127[»]
    3U5IX-ray3.00Y1-127[»]
    4B6Aelectron microscopy8.10Y1-127[»]
    4BYNelectron microscopy4.30Y2-127[»]
    4BYUelectron microscopy6.60Y2-127[»]
    4CUWelectron microscopy3.70Y1-127[»]
    ProteinModelPortaliP05743.
    SMRiP05743. Positions 2-127.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP05743.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L24P family.Curated

    Phylogenomic databases

    GeneTreeiENSGT00390000014165.
    HOGENOMiHOG000216571.
    KOiK02898.
    OMAiCITENIR.
    OrthoDBiEOG747PX1.

    Family and domain databases

    Gene3Di2.30.30.30. 1 hit.
    InterProiIPR005824. KOW.
    IPR014722. Rib_L2_dom2.
    IPR005825. Ribosomal_L24/26_CS.
    IPR005756. Ribosomal_L26/L24P_euk/arc.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view]
    PANTHERiPTHR11143. PTHR11143. 1 hit.
    PfamiPF00467. KOW. 1 hit.
    [Graphical view]
    SMARTiSM00739. KOW. 1 hit.
    [Graphical view]
    SUPFAMiSSF50104. SSF50104. 1 hit.
    TIGRFAMsiTIGR01080. rplX_A_E. 1 hit.
    PROSITEiPS01108. RIBOSOMAL_L24. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P05743-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKQSLDVSS DRRKARKAYF TAPSSQRRVL LSAPLSKELR AQYGIKALPI    50
    RRDDEVLVVR GSKKGQEGKI SSVYRLKFAV QVDKVTKEKV NGASVPINLH 100
    PSKLVITKLH LDKDRKALIQ RKGGKLE 127
    Length:127
    Mass (Da):14,234
    Last modified:January 23, 2007 - v3
    Checksum:i3888654AC1587E8E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U19028 Genomic DNA. Translation: AAB67254.1.
    BK006945 Genomic DNA. Translation: DAA09649.1.
    PIRiS51347.
    RefSeqiNP_013448.1. NM_001182233.1.

    Genome annotation databases

    EnsemblFungiiYLR344W; YLR344W; YLR344W.
    GeneIDi851058.
    KEGGisce:YLR344W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U19028 Genomic DNA. Translation: AAB67254.1 .
    BK006945 Genomic DNA. Translation: DAA09649.1 .
    PIRi S51347.
    RefSeqi NP_013448.1. NM_001182233.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1K5Y model - U 9-123 [» ]
    1S1I electron microscopy 11.70 U 2-127 [» ]
    1VW8 electron microscopy 6.10 Z 1-127 [» ]
    1VWU electron microscopy 6.10 Z 1-127 [» ]
    2WW9 electron microscopy 8.60 L 1-127 [» ]
    2WWA electron microscopy 8.90 L 1-127 [» ]
    2WWB electron microscopy 6.48 L 1-127 [» ]
    3IZS electron microscopy - Y 1-123 [» ]
    3J65 electron microscopy 8.70 X 1-127 [» ]
    3O58 X-ray 4.00 X 1-127 [» ]
    3O5H X-ray 4.00 X 1-127 [» ]
    3U5E X-ray 3.00 Y 1-127 [» ]
    3U5I X-ray 3.00 Y 1-127 [» ]
    4B6A electron microscopy 8.10 Y 1-127 [» ]
    4BYN electron microscopy 4.30 Y 2-127 [» ]
    4BYU electron microscopy 6.60 Y 2-127 [» ]
    4CUW electron microscopy 3.70 Y 1-127 [» ]
    ProteinModelPortali P05743.
    SMRi P05743. Positions 2-127.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 31607. 37 interactions.
    DIPi DIP-5584N.
    IntActi P05743. 7 interactions.
    MINTi MINT-8285368.
    STRINGi 4932.YLR344W.

    Proteomic databases

    PeptideAtlasi P05743.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YLR344W ; YLR344W ; YLR344W .
    GeneIDi 851058.
    KEGGi sce:YLR344W.

    Organism-specific databases

    SGDi S000004336. RPL26A.

    Phylogenomic databases

    GeneTreei ENSGT00390000014165.
    HOGENOMi HOG000216571.
    KOi K02898.
    OMAi CITENIR.
    OrthoDBi EOG747PX1.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32420-MONOMER.
    Reactomei REACT_188965. SRP-dependent cotranslational protein targeting to membrane.
    REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_217188. Formation of a pool of free 40S subunits.

    Miscellaneous databases

    EvolutionaryTracei P05743.
    NextBioi 967681.

    Gene expression databases

    Genevestigatori P05743.

    Family and domain databases

    Gene3Di 2.30.30.30. 1 hit.
    InterProi IPR005824. KOW.
    IPR014722. Rib_L2_dom2.
    IPR005825. Ribosomal_L24/26_CS.
    IPR005756. Ribosomal_L26/L24P_euk/arc.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view ]
    PANTHERi PTHR11143. PTHR11143. 1 hit.
    Pfami PF00467. KOW. 1 hit.
    [Graphical view ]
    SMARTi SM00739. KOW. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50104. SSF50104. 1 hit.
    TIGRFAMsi TIGR01080. rplX_A_E. 1 hit.
    PROSITEi PS01108. RIBOSOMAL_L24. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
      Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H.
      , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
      Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. "Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes."
      Otaka E., Higo K., Itoh T.
      Mol. Gen. Genet. 195:544-546(1984) [PubMed] [Europe PMC] [Abstract]
      Cited for: PARTIAL PROTEIN SEQUENCE OF 2-41, CLEAVAGE OF INITIATOR METHIONINE.
    4. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
      Planta R.J., Mager W.H.
      Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NOMENCLATURE, SUBUNIT.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. "Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-ribosome and subunit-subunit interactions."
      Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G., Frank J.
      Cell 107:373-386(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: 3D-STRUCTURE MODELING OF 9-123, ELECTRON MICROSCOPY.
    7. "Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation."
      Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R., Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J.
      EMBO J. 23:1008-1019(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: 3D-STRUCTURE MODELING, ELECTRON MICROSCOPY.
    8. "Crystal structure of the eukaryotic ribosome."
      Ben-Shem A., Jenner L., Yusupova G., Yusupov M.
      Science 330:1203-1209(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
    9. Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME.

    Entry informationi

    Entry nameiRL26A_YEAST
    AccessioniPrimary (citable) accession number: P05743
    Secondary accession number(s): D6VYY3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1988
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 131 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    There are 2 genes for L26 in yeast.

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families
    4. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    5. Yeast chromosome XII
      Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

    External Data

    Dasty 3