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P05738

- RL9A_YEAST

UniProt

P05738 - RL9A_YEAST

Protein

60S ribosomal protein L9-A

Gene

RPL9A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 135 (01 Oct 2014)
      Sequence version 2 (01 Dec 1992)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. rRNA binding Source: InterPro
    2. structural constituent of ribosome Source: SGD

    GO - Biological processi

    1. cytoplasmic translation Source: SGD

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30641-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    60S ribosomal protein L9-A
    Alternative name(s):
    L8
    RP24
    YL11
    Gene namesi
    Name:RPL9A
    Synonyms:RPL8A, RPL9
    Ordered Locus Names:YGL147C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VII

    Organism-specific databases

    CYGDiYGL147c.
    SGDiS000003115. RPL9A.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytosolic large ribosomal subunit Source: SGD

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 19119160S ribosomal protein L9-APRO_0000131111Add
    BLAST

    Proteomic databases

    MaxQBiP05738.
    PeptideAtlasiP05738.

    Expressioni

    Gene expression databases

    GenevestigatoriP05738.

    Interactioni

    Subunit structurei

    Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

    Protein-protein interaction databases

    BioGridi33105. 118 interactions.
    DIPiDIP-4826N.
    IntActiP05738. 9 interactions.
    MINTiMINT-493534.
    STRINGi4932.YGL147C.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1K5Ymodel-H7-184[»]
    1S1Ielectron microscopy11.70H1-191[»]
    1VW8electron microscopy6.10I1-191[»]
    1VWUelectron microscopy6.10I1-191[»]
    3IZSelectron microscopy-F1-191[»]
    3J16electron microscopy-F1-191[»]
    3J65electron microscopy8.70F1-191[»]
    3O58X-ray4.00I1-191[»]
    3O5HX-ray4.00I1-191[»]
    3U5EX-ray3.00H1-191[»]
    3U5IX-ray3.00H1-191[»]
    4B6Aelectron microscopy8.10H1-191[»]
    4BYNelectron microscopy4.30H1-191[»]
    4BYUelectron microscopy6.60H1-191[»]
    4CUWelectron microscopy3.70H1-191[»]
    ProteinModelPortaliP05738.
    SMRiP05738. Positions 1-191.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP05738.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L6P family.Curated

    Phylogenomic databases

    GeneTreeiENSGT00390000015224.
    HOGENOMiHOG000039905.
    KOiK02940.
    OMAiEFVGQTA.
    OrthoDBiEOG7FR7TQ.

    Family and domain databases

    Gene3Di3.90.930.12. 2 hits.
    InterProiIPR000702. Ribosomal_L6.
    IPR020040. Ribosomal_L6_a/b-dom.
    IPR002359. Ribosomal_L6_CS2.
    [Graphical view]
    PANTHERiPTHR11655. PTHR11655. 1 hit.
    PfamiPF00347. Ribosomal_L6. 2 hits.
    [Graphical view]
    PIRSFiPIRSF002162. Ribosomal_L6. 1 hit.
    SUPFAMiSSF56053. SSF56053. 2 hits.
    PROSITEiPS00700. RIBOSOMAL_L6_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P05738-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKYIQTEQQI EVPEGVTVSI KSRIVKVVGP RGTLTKNLKH IDVTFTKVNN    50
    QLIKVAVHNG GRKHVAALRT VKSLVDNMIT GVTKGYKYKM RYVYAHFPIN 100
    VNIVEKDGAK FIEVRNFLGD KKIRNVPVRD GVTIEFSTNV KDEIVLSGNS 150
    VEDVSQNAAD LQQICRVRNK DIRKFLDGIY VSHKGFITED L 191
    Length:191
    Mass (Da):21,569
    Last modified:December 1, 1992 - v2
    Checksum:iCAA342FCDD061175
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60190 Genomic DNA. Translation: CAA42746.1.
    X99960 Genomic DNA. Translation: CAA68215.1.
    Z72669 Genomic DNA. Translation: CAA96859.1.
    BK006941 Genomic DNA. Translation: DAA07963.1.
    PIRiS19077. R5BYL9.
    RefSeqiNP_011368.3. NM_001181012.3.

    Genome annotation databases

    EnsemblFungiiYGL147C; YGL147C; YGL147C.
    GeneIDi852730.
    KEGGisce:YGL147C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60190 Genomic DNA. Translation: CAA42746.1 .
    X99960 Genomic DNA. Translation: CAA68215.1 .
    Z72669 Genomic DNA. Translation: CAA96859.1 .
    BK006941 Genomic DNA. Translation: DAA07963.1 .
    PIRi S19077. R5BYL9.
    RefSeqi NP_011368.3. NM_001181012.3.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1K5Y model - H 7-184 [» ]
    1S1I electron microscopy 11.70 H 1-191 [» ]
    1VW8 electron microscopy 6.10 I 1-191 [» ]
    1VWU electron microscopy 6.10 I 1-191 [» ]
    3IZS electron microscopy - F 1-191 [» ]
    3J16 electron microscopy - F 1-191 [» ]
    3J65 electron microscopy 8.70 F 1-191 [» ]
    3O58 X-ray 4.00 I 1-191 [» ]
    3O5H X-ray 4.00 I 1-191 [» ]
    3U5E X-ray 3.00 H 1-191 [» ]
    3U5I X-ray 3.00 H 1-191 [» ]
    4B6A electron microscopy 8.10 H 1-191 [» ]
    4BYN electron microscopy 4.30 H 1-191 [» ]
    4BYU electron microscopy 6.60 H 1-191 [» ]
    4CUW electron microscopy 3.70 H 1-191 [» ]
    ProteinModelPortali P05738.
    SMRi P05738. Positions 1-191.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33105. 118 interactions.
    DIPi DIP-4826N.
    IntActi P05738. 9 interactions.
    MINTi MINT-493534.
    STRINGi 4932.YGL147C.

    Proteomic databases

    MaxQBi P05738.
    PeptideAtlasi P05738.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YGL147C ; YGL147C ; YGL147C .
    GeneIDi 852730.
    KEGGi sce:YGL147C.

    Organism-specific databases

    CYGDi YGL147c.
    SGDi S000003115. RPL9A.

    Phylogenomic databases

    GeneTreei ENSGT00390000015224.
    HOGENOMi HOG000039905.
    KOi K02940.
    OMAi EFVGQTA.
    OrthoDBi EOG7FR7TQ.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30641-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P05738.
    NextBioi 972123.

    Gene expression databases

    Genevestigatori P05738.

    Family and domain databases

    Gene3Di 3.90.930.12. 2 hits.
    InterProi IPR000702. Ribosomal_L6.
    IPR020040. Ribosomal_L6_a/b-dom.
    IPR002359. Ribosomal_L6_CS2.
    [Graphical view ]
    PANTHERi PTHR11655. PTHR11655. 1 hit.
    Pfami PF00347. Ribosomal_L6. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF002162. Ribosomal_L6. 1 hit.
    SUPFAMi SSF56053. SSF56053. 2 hits.
    PROSITEi PS00700. RIBOSOMAL_L6_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and characterisation of a yeast homolog of the mammalian ribosomal protein L9."
      Jones D.G.L., Reusser U., Braus G.H.
      Nucleic Acids Res. 19:5785-5785(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "The sequence of a nearly unclonable 22.8 kb segment on the left arm chromosome VII from Saccharomyces cerevisiae reveals ARO2, RPL9A, TIP1, MRF1 genes and six new open reading frames."
      Voet M., Defoor E., Verhasselt P., Riles L., Robben J., Volckaert G.
      Yeast 13:177-182(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 96604 / S288c / FY1679.
    3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
      Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
      , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
      Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. "Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes."
      Otaka E., Higo K., Itoh T.
      Mol. Gen. Genet. 195:544-546(1984) [PubMed] [Europe PMC] [Abstract]
      Cited for: PARTIAL PROTEIN SEQUENCE OF 1-40.
    6. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
      Planta R.J., Mager W.H.
      Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NOMENCLATURE, SUBUNIT.
    7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    8. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    9. "Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-ribosome and subunit-subunit interactions."
      Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G., Frank J.
      Cell 107:373-386(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: 3D-STRUCTURE MODELING OF 7-184, ELECTRON MICROSCOPY.
    10. "Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation."
      Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R., Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J.
      EMBO J. 23:1008-1019(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: 3D-STRUCTURE MODELING, ELECTRON MICROSCOPY.
    11. "Crystal structure of the eukaryotic ribosome."
      Ben-Shem A., Jenner L., Yusupova G., Yusupov M.
      Science 330:1203-1209(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
    12. Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME.

    Entry informationi

    Entry nameiRL9A_YEAST
    AccessioniPrimary (citable) accession number: P05738
    Secondary accession number(s): D6VU02
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1988
    Last sequence update: December 1, 1992
    Last modified: October 1, 2014
    This is version 135 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 52400 molecules/cell in log phase SD medium.1 Publication
    There are 2 genes for L9 in yeast.

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families
    4. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    5. Yeast chromosome VII
      Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

    External Data

    Dasty 3