Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

T-cell surface glycoprotein CD4

Gene

CD4

Organism
Ovis aries (Sheep)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.

GO - Biological processi

  • adaptive immune response Source: UniProtKB-KW
  • T cell differentiation Source: UniProtKB
  • T cell selection Source: UniProtKB

Keywordsi

Biological processAdaptive immunity, Immunity

Names & Taxonomyi

Protein namesi
Recommended name:
T-cell surface glycoprotein CD4
Alternative name(s):
T-cell surface antigen T4/Leu-3
CD_antigen: CD4
Gene namesi
Name:CD4
OrganismiOvis aries (Sheep)
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis
Proteomesi
  • UP000002356 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000726751 – ›20T-cell surface glycoprotein CD4Add BLAST›20

Interactioni

Subunit structurei

Associates with p56-LCK. Interacts with SPG21 (By similarity).By similarity

Family & Domainsi

Keywords - Domaini

Immunoglobulin domain

Sequencei

Sequence statusi: Fragment.

P05542-1 [UniParc]FASTAAdd to basket

« Hide

        10         20
KAVVLGKAGG TAELPCQASQ
Length:20
Mass (Da):1,928
Last modified:November 1, 1988 - v1
Checksum:i421F09570FEA97EE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei201

Sequence databases

PIRiB47642.
UniGeneiOar.1014.

Similar proteinsi

Entry informationi

Entry nameiCD4_SHEEP
AccessioniPrimary (citable) accession number: P05542
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: November 1, 1988
Last modified: June 8, 2016
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome