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P05491 (COX2_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 2

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide II
Gene names
Name:COX2
Synonyms:COII, COXII
Encoded onMitochondrion
OrganismGlycine max (Soybean) (Glycine hispida)
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja

Protein attributes

Sequence length260 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Cofactor

Copper A.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein.

Miscellaneous

The gene coding for this protein is probably silent. Soybean nuclear genome encode an active cox2.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 260260Cytochrome c oxidase subunit 2
PRO_0000183693

Regions

Topological domain1 – 3939Mitochondrial intermembrane Potential
Transmembrane40 – 6122Helical; Potential
Topological domain62 – 7615Mitochondrial matrix Potential
Transmembrane77 – 10428Helical; Potential
Topological domain105 – 260156Mitochondrial intermembrane Potential

Sites

Metal binding1861Copper A Probable
Metal binding2211Copper A Probable
Metal binding2251Copper A Probable
Metal binding2291Copper A Probable

Sequences

Sequence LengthMass (Da)Tools
P05491 [UniParc].

Last modified November 1, 1995. Version 2.
Checksum: 400FCAE14AD98000

FASTA26029,437
        10         20         30         40         50         60 
MKFEWLFLTI APCDAAEPWQ LGFQDAATPM MQGIIDLHHD IFFFLILILV FVSRILVRAL 

        70         80         90        100        110        120 
WHFHYKKNPI PQRIVHGTTI EILRTIFPSI IPMFIAIPSF ALLYSMDEVV VDPAITIKAI 

       130        140        150        160        170        180 
GHQWYRTYEY SDYNSSDEQS LTFDSYTIPE DDLELGQSRL LEVDNRVVVP AKTHLRIIVT 

       190        200        210        220        230        240 
PADVPHSWAV PSLGVKCDAV PGRLNQISIS VQREGVYYGQ CSEICGTNHA FTPIVVEAVP 

       250        260 
SKDYGSRVFN QLIPQTTGEA 

« Hide

References

[1]"Cytochrome oxidase subunit II gene is adjacent to an initiator methionine tRNA gene in soybean mitochondrial DNA."
Grabau E.A.
Curr. Genet. 11:287-293(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X04825 Genomic DNA. Translation: CAA28508.1.
PIRS07169.
RefSeqYP_007516925.1. NC_020455.1.

3D structure databases

ProteinModelPortalP05491.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID15308623.
KEGGgmx:15308623.

Phylogenomic databases

KOK02261.

Gene expression databases

GenevestigatorP05491.

Family and domain databases

Gene3D1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProIPR008972. Cupredoxin.
IPR014222. Cyt_c_oxidase_su2.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
[Graphical view]
PfamPF00116. COX2. 1 hit.
PF02790. COX2_TM. 1 hit.
[Graphical view]
SUPFAMSSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
TIGRFAMsTIGR02866. CoxB. 1 hit.
PROSITEPS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX2_SOYBN
AccessionPrimary (citable) accession number: P05491
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families