Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Caltractin

Gene
N/A
Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

This calcium-binding protein is found in the basal body complexes (the functional homolog of the centrosome in animal cell). In mitotic cells it is specifically associated with the poles of the mitotic spindles at the sites of the duplicated basal body complexes.

Miscellaneous

Binds four moles of calcium per mole of protein.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi38 – 491CuratedAdd BLAST12
Calcium bindingi74 – 852CuratedAdd BLAST12
Calcium bindingi111 – 1223CuratedAdd BLAST12
Calcium bindingi147 – 1584CuratedAdd BLAST12

GO - Molecular functioni

  • calcium ion binding Source: InterPro
  • dynein heavy chain binding Source: GO_Central

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Mitosis
LigandCalcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Caltractin
Alternative name(s):
20 kDa calcium-binding protein
Centrin
OrganismiChlamydomonas reinhardtii (Chlamydomonas smithii)
Taxonomic identifieri3055 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesChlamydomonadaceaeChlamydomonas

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000735711 – 169CaltractinAdd BLAST169

Proteomic databases

PaxDbiP05434.
ProMEXiP05434.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
O123692EBI-983707,EBI-983753From Laguna Negra orthohantavirus.

GO - Molecular functioni

  • dynein heavy chain binding Source: GO_Central

Protein-protein interaction databases

IntActiP05434. 1 interactor.

Structurei

Secondary structure

1169
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi24 – 37Combined sources14
Beta strandi43 – 45Combined sources3
Helixi47 – 56Combined sources10
Helixi63 – 73Combined sources11
Beta strandi75 – 82Combined sources8
Helixi83 – 110Combined sources28
Beta strandi115 – 118Combined sources4
Helixi120 – 129Combined sources10
Helixi136 – 146Combined sources11
Beta strandi149 – 152Combined sources4
Helixi156 – 163Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OQPNMR-A95-169[»]
2AMINMR-A1-94[»]
3QRXX-ray2.20A1-169[»]
ProteinModelPortaliP05434.
SMRiP05434.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP05434.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 60EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini61 – 96EF-hand 2PROSITE-ProRule annotationAdd BLAST36
Domaini98 – 133EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini134 – 169EF-hand 4PROSITE-ProRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the centrin family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0028. Eukaryota.
COG5126. LUCA.
KOiK16465.
OMAiEPRKEEM.

Family and domain databases

CDDicd00051. EFh. 1 hit.
InterProiView protein in InterPro
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
PfamiView protein in Pfam
PF13499. EF-hand_7. 2 hits.
SMARTiView protein in SMART
SM00054. EFh. 4 hits.
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.

Sequencei

Sequence statusi: Complete.

P05434-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYKAKTVVS ARRDQKKGRV GLTEEQKQEI REAFDLFDTD GSGTIDAKEL
60 70 80 90 100
KVAMRALGFE PKKEEIKKMI SEIDKDGSGT IDFEEFLTMM TAKMGERDSR
110 120 130 140 150
EEILKAFRLF DDDNSGTITI KDLRRVAKEL GENLTEEELQ EMIAEADRND
160
DNEIDEDEFI RIMKKTSLF
Length:169
Mass (Da):19,459
Last modified:November 1, 1988 - v1
Checksum:i731D171794EAD983
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X12634 mRNA. Translation: CAA31163.1.
X57973 Genomic DNA. Translation: CAA41039.1.
PIRiA28216. BCKM.
RefSeqiXP_001699499.1. XM_001699447.1.
UniGeneiCre.13742.

Genome annotation databases

EnsemblPlantsiEDO98562; EDO98562; CHLREDRAFT_159554.
GeneIDi5725094.
GrameneiEDO98562; EDO98562; CHLREDRAFT_159554.
KEGGicre:CHLREDRAFT_159554.

Similar proteinsi

Entry informationi

Entry nameiCATR_CHLRE
AccessioniPrimary (citable) accession number: P05434
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: November 1, 1988
Last modified: October 25, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families