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P05416

- GLGA_SALTY

UniProt

P05416 - GLGA_SALTY

Protein

Glycogen synthase

Gene

glgA

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 2 (19 Dec 2001)
      Previous versions | rss
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    Functioni

    Synthesizes alpha-1,4-glucan chains using ADP-glucose.

    Catalytic activityi

    ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151ADP-glucoseBy similarity

    GO - Molecular functioni

    1. starch synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Glycogen biosynthesis

    Enzyme and pathway databases

    BioCyciSENT99287:GCTI-3558-MONOMER.
    UniPathwayiUPA00164.

    Protein family/group databases

    CAZyiGT5. Glycosyltransferase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycogen synthase (EC:2.4.1.21)
    Alternative name(s):
    Starch [bacterial glycogen] synthase
    Gene namesi
    Name:glgA
    Ordered Locus Names:STM3535
    OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    Taxonomic identifieri99287 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001014: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 477477Glycogen synthasePRO_0000188644Add
    BLAST

    Proteomic databases

    PRIDEiP05416.

    Interactioni

    Protein-protein interaction databases

    STRINGi99287.STM3535.

    Structurei

    3D structure databases

    ProteinModelPortaliP05416.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    HOGENOMiHOG000294941.
    KOiK00703.
    OMAiPYHDESQ.
    OrthoDBiEOG6JTC6Z.
    PhylomeDBiP05416.

    Family and domain databases

    HAMAPiMF_00484. Glycogen_synth.
    InterProiIPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view]
    PfamiPF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02095. glgA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P05416-1 [UniParc]FASTAAdd to Basket

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    MQVLHVCSEM FPLLKTGGLA DVIGALPAAQ IADGVDVRVL LPGFPDIRRG    50
    IPDAHVVSRR DTFAGKISLL FGHYNGVGIY LIDAPHLYER PGSPYHDTNL 100
    YAYTDNVLRF ALLGWVGCEM ACGLDPFWRP DVVHAHDWHA GLAPAYLAAR 150
    GRPAKSVFTV HNLAYQGMFY AKHMDDIELP WSFFNMHGLE FNGQLSFLKA 200
    GLYYADHITA VSPTYAREIT EPQFAYGMEG LLRQRHLEGR LSGILNGVDE 250
    KIWNPESDLL LASRYTRDTL EEKAENKRQL QIAMGLKVND KVPLFAVVSR 300
    LTNQKGLDLV LEALPGLLEQ GGQLALLGAG DPVLQEGFLA AAAEHPGQVG 350
    VQIGYHEAFS HRIMGGADVI LVPSRFEPCG LTQLYGLKYG TLPLVRRTGG 400
    LADTVSDSSL ENLADGIASG FVFEDSNAWS LLRAIRRAFV LWSRPSLWRF 450
    VQRQAMAMDF SWQVAAKSYR ELYYRLK 477
    Length:477
    Mass (Da):52,946
    Last modified:December 19, 2001 - v2
    Checksum:i004D2E49B6AA380D
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti29 – 291A → R in AAA27133. (PubMed:3040691)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL22395.1.
    M17363 Genomic DNA. Translation: AAA27133.1.
    RefSeqiNP_462436.1. NC_003197.1.

    Genome annotation databases

    EnsemblBacteriaiAAL22395; AAL22395; STM3535.
    GeneIDi1255058.
    KEGGistm:STM3535.
    PATRICi32385879. VBISalEnt20916_3737.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL22395.1 .
    M17363 Genomic DNA. Translation: AAA27133.1 .
    RefSeqi NP_462436.1. NC_003197.1.

    3D structure databases

    ProteinModelPortali P05416.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 99287.STM3535.

    Protein family/group databases

    CAZyi GT5. Glycosyltransferase Family 5.

    Proteomic databases

    PRIDEi P05416.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL22395 ; AAL22395 ; STM3535 .
    GeneIDi 1255058.
    KEGGi stm:STM3535.
    PATRICi 32385879. VBISalEnt20916_3737.

    Phylogenomic databases

    HOGENOMi HOG000294941.
    KOi K00703.
    OMAi PYHDESQ.
    OrthoDBi EOG6JTC6Z.
    PhylomeDBi P05416.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .
    BioCyci SENT99287:GCTI-3558-MONOMER.

    Family and domain databases

    HAMAPi MF_00484. Glycogen_synth.
    InterProi IPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view ]
    Pfami PF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02095. glgA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LT2 / SGSC1412 / ATCC 700720.
    2. "Biosynthesis of bacterial glycogen: primary structure of Salmonella typhimurium ADPglucose synthetase as deduced from the nucleotide sequence of the glgC gene."
      Leung P.S.C., Preiss J.
      J. Bacteriol. 169:4355-4360(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-29.

    Entry informationi

    Entry nameiGLGA_SALTY
    AccessioniPrimary (citable) accession number: P05416
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1988
    Last sequence update: December 19, 2001
    Last modified: October 1, 2014
    This is version 95 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3