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P05160

- F13B_HUMAN

UniProt

P05160 - F13B_HUMAN

Protein

Coagulation factor XIII B chain

Gene

F13B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 148 (01 Oct 2014)
      Sequence version 3 (17 Apr 2007)
      Previous versions | rss
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    Functioni

    The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin.

    GO - Biological processi

    1. blood coagulation Source: Reactome

    Keywords - Biological processi

    Blood coagulation, Hemostasis

    Enzyme and pathway databases

    ReactomeiREACT_1439. Common Pathway.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Coagulation factor XIII B chain
    Alternative name(s):
    Fibrin-stabilizing factor B subunit
    Protein-glutamine gamma-glutamyltransferase B chain
    Transglutaminase B chain
    Gene namesi
    Name:F13B
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:3534. F13B.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Involvement in diseasei

    Factor XIII subunit B deficiency (FA13BD) [MIM:613235]: An autosomal recessive hematologic disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.2 Publications
    Note: The disease is caused by mutations affecting the gene represented in this entry.
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti450 – 4501C → F in FA13BD. 1 Publication
    VAR_007475

    Keywords - Diseasei

    Disease mutation

    Organism-specific databases

    MIMi134580. gene+phenotype.
    613235. phenotype.
    Orphaneti331. Congenital factor XIII deficiency.
    PharmGKBiPA27944.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Add
    BLAST
    Chaini21 – 661641Coagulation factor XIII B chainPRO_0000021222Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi25 ↔ 76PROSITE-ProRule annotation
    Disulfide bondi59 ↔ 87PROSITE-ProRule annotation
    Disulfide bondi91 ↔ 135PROSITE-ProRule annotation
    Disulfide bondi118 ↔ 146PROSITE-ProRule annotation
    Disulfide bondi153 ↔ 197PROSITE-ProRule annotation
    Glycosylationi162 – 1621N-linked (GlcNAc...)1 Publication
    Disulfide bondi180 ↔ 208PROSITE-ProRule annotation
    Disulfide bondi213 ↔ 255PROSITE-ProRule annotation
    Disulfide bondi241 ↔ 267PROSITE-ProRule annotation
    Disulfide bondi274 ↔ 316PROSITE-ProRule annotation
    Disulfide bondi302 ↔ 327PROSITE-ProRule annotation
    Disulfide bondi336 ↔ 378PROSITE-ProRule annotation
    Disulfide bondi364 ↔ 389PROSITE-ProRule annotation
    Disulfide bondi396 ↔ 439PROSITE-ProRule annotation
    Disulfide bondi425 ↔ 450PROSITE-ProRule annotation
    Disulfide bondi454 ↔ 505PROSITE-ProRule annotation
    Disulfide bondi486 ↔ 515PROSITE-ProRule annotation
    Disulfide bondi524 ↔ 567PROSITE-ProRule annotation
    Glycosylationi545 – 5451N-linked (GlcNAc...)1 Publication
    Disulfide bondi553 ↔ 578PROSITE-ProRule annotation
    Disulfide bondi582 ↔ 636PROSITE-ProRule annotation
    Disulfide bondi616 ↔ 646PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiP05160.
    PeptideAtlasiP05160.
    PRIDEiP05160.

    PTM databases

    PhosphoSiteiP05160.

    Expressioni

    Gene expression databases

    BgeeiP05160.
    CleanExiHS_F13B.
    GenevestigatoriP05160.

    Organism-specific databases

    HPAiHPA003827.

    Interactioni

    Subunit structurei

    Tetramer of two A chains and two B chains.

    Protein-protein interaction databases

    BioGridi108463. 2 interactions.
    STRINGi9606.ENSP00000356382.

    Structurei

    3D structure databases

    ProteinModelPortaliP05160.
    SMRiP05160. Positions 23-649.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini24 – 8865Sushi 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini89 – 14860Sushi 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini151 – 21060Sushi 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini211 – 26959Sushi 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini272 – 32958Sushi 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini334 – 39158Sushi 6PROSITE-ProRule annotationAdd
    BLAST
    Domaini394 – 45259Sushi 7PROSITE-ProRule annotationAdd
    BLAST
    Domaini453 – 51664Sushi 8PROSITE-ProRule annotationAdd
    BLAST
    Domaini522 – 58059Sushi 9PROSITE-ProRule annotationAdd
    BLAST
    Domaini581 – 64767Sushi 10PROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi617 – 6193Cell attachment site

    Sequence similaritiesi

    Contains 10 Sushi (CCP/SCR) domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Signal, Sushi

    Phylogenomic databases

    eggNOGiNOG146710.
    HOGENOMiHOG000049250.
    HOVERGENiHBG005626.
    InParanoidiP05160.
    KOiK03906.
    OMAiNFGWYPE.
    OrthoDBiEOG7CNZF8.
    PhylomeDBiP05160.
    TreeFamiTF326157.

    Family and domain databases

    InterProiIPR000436. Sushi_SCR_CCP.
    [Graphical view]
    PfamiPF00084. Sushi. 8 hits.
    [Graphical view]
    SMARTiSM00032. CCP. 8 hits.
    [Graphical view]
    SUPFAMiSSF57535. SSF57535. 10 hits.
    PROSITEiPS50923. SUSHI. 7 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P05160-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLKNLTFII ILIISGELYA EEKPCGFPHV ENGRIAQYYY TFKSFYFPMS    50
    IDKKLSFFCL AGYTTESGRQ EEQTTCTTEG WSPEPRCFKK CTKPDLSNGY 100
    ISDVKLLYKI QENMRYGCAS GYKTTGGKDE EVVQCLSDGW SSQPTCRKEH 150
    ETCLAPELYN GNYSTTQKTF KVKDKVQYEC ATGYYTAGGK KTEEVECLTY 200
    GWSLTPKCTK LKCSSLRLIE NGYFHPVKQT YEEGDVVQFF CHENYYLSGS 250
    DLIQCYNFGW YPESPVCEGR RNRCPPPPLP INSKIQTHST TYRHGEIVHI 300
    ECELNFEIHG SAEIRCEDGK WTEPPKCIEG QEKVACEEPP FIENGAANLH 350
    SKIYYNGDKV TYACKSGYLL HGSNEITCNR GKWTLPPECV ENNENCKHPP 400
    VVMNGAVADG ILASYATGSS VEYRCNEYYL LRGSKISRCE QGKWSSPPVC 450
    LEPCTVNVDY MNRNNIEMKW KYEGKVLHGD LIDFVCKQGY DLSPLTPLSE 500
    LSVQCNRGEV KYPLCTRKES KGMCTSPPLI KHGVIISSTV DTYENGSSVE 550
    YRCFDHHFLE GSREAYCLDG MWTTPPLCLE PCTLSFTEME KNNLLLKWDF 600
    DNRPHILHGE YIEFICRGDT YPAELYITGS ILRMQCDRGQ LKYPRCIPRQ 650
    STLSYQEPLR T 661
    Length:661
    Mass (Da):75,511
    Last modified:April 17, 2007 - v3
    Checksum:i57A2FD2A0E35B812
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti49 – 491M → V.1 Publication
    Corresponds to variant rs6002 [ dbSNP | Ensembl ].
    VAR_013930
    Natural varianti115 – 1151R → H.4 Publications
    Corresponds to variant rs6003 [ dbSNP | Ensembl ].
    VAR_013931
    Natural varianti342 – 3421I → T.1 Publication
    Corresponds to variant rs17514281 [ dbSNP | Ensembl ].
    VAR_020612
    Natural varianti350 – 3501H → R.2 Publications
    Corresponds to variant rs5999 [ dbSNP | Ensembl ].
    VAR_013932
    Natural varianti388 – 3881E → V.1 Publication
    Corresponds to variant rs5991 [ dbSNP | Ensembl ].
    VAR_013933
    Natural varianti450 – 4501C → F in FA13BD. 1 Publication
    VAR_007475
    Natural varianti529 – 5291L → P.1 Publication
    Corresponds to variant rs17549671 [ dbSNP | Ensembl ].
    VAR_020613
    Natural varianti543 – 5431Y → S.1 Publication
    Corresponds to variant rs6001 [ dbSNP | Ensembl ].
    VAR_013934
    Natural varianti569 – 5691D → E.3 Publications
    Corresponds to variant rs6000 [ dbSNP | Ensembl ].
    VAR_013935

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64554 Genomic DNA. Translation: AAA51821.1. Sequence problems.
    M14057 mRNA. Translation: AAA88042.1.
    AK290560 mRNA. Translation: BAF83249.1.
    AY692223 Genomic DNA. Translation: AAT85802.1.
    AL353809 Genomic DNA. Translation: CAH72549.1.
    X51823 mRNA. Translation: CAA36123.1.
    CCDSiCCDS1388.1.
    PIRiA36397. KFHU13.
    RefSeqiNP_001985.2. NM_001994.2.
    UniGeneiHs.435782.

    Genome annotation databases

    EnsembliENST00000367412; ENSP00000356382; ENSG00000143278.
    GeneIDi2165.
    KEGGihsa:2165.
    UCSCiuc001gtt.1. human.

    Polymorphism databases

    DMDMi145559473.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Web resourcesi

    SHMPD

    The Singapore human mutation and polymorphism database

    Wikipedia

    Factor XIII entry

    SeattleSNPs

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64554 Genomic DNA. Translation: AAA51821.1 . Sequence problems.
    M14057 mRNA. Translation: AAA88042.1 .
    AK290560 mRNA. Translation: BAF83249.1 .
    AY692223 Genomic DNA. Translation: AAT85802.1 .
    AL353809 Genomic DNA. Translation: CAH72549.1 .
    X51823 mRNA. Translation: CAA36123.1 .
    CCDSi CCDS1388.1.
    PIRi A36397. KFHU13.
    RefSeqi NP_001985.2. NM_001994.2.
    UniGenei Hs.435782.

    3D structure databases

    ProteinModelPortali P05160.
    SMRi P05160. Positions 23-649.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 108463. 2 interactions.
    STRINGi 9606.ENSP00000356382.

    PTM databases

    PhosphoSitei P05160.

    Polymorphism databases

    DMDMi 145559473.

    Proteomic databases

    PaxDbi P05160.
    PeptideAtlasi P05160.
    PRIDEi P05160.

    Protocols and materials databases

    DNASUi 2165.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000367412 ; ENSP00000356382 ; ENSG00000143278 .
    GeneIDi 2165.
    KEGGi hsa:2165.
    UCSCi uc001gtt.1. human.

    Organism-specific databases

    CTDi 2165.
    GeneCardsi GC01M197008.
    H-InvDB HIX0028859.
    HGNCi HGNC:3534. F13B.
    HPAi HPA003827.
    MIMi 134580. gene+phenotype.
    613235. phenotype.
    neXtProti NX_P05160.
    Orphaneti 331. Congenital factor XIII deficiency.
    PharmGKBi PA27944.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG146710.
    HOGENOMi HOG000049250.
    HOVERGENi HBG005626.
    InParanoidi P05160.
    KOi K03906.
    OMAi NFGWYPE.
    OrthoDBi EOG7CNZF8.
    PhylomeDBi P05160.
    TreeFami TF326157.

    Enzyme and pathway databases

    Reactomei REACT_1439. Common Pathway.

    Miscellaneous databases

    GeneWikii F13B.
    GenomeRNAii 2165.
    NextBioi 8743.
    PROi P05160.
    SOURCEi Search...

    Gene expression databases

    Bgeei P05160.
    CleanExi HS_F13B.
    Genevestigatori P05160.

    Family and domain databases

    InterProi IPR000436. Sushi_SCR_CCP.
    [Graphical view ]
    Pfami PF00084. Sushi. 8 hits.
    [Graphical view ]
    SMARTi SM00032. CCP. 8 hits.
    [Graphical view ]
    SUPFAMi SSF57535. SSF57535. 10 hits.
    PROSITEi PS50923. SUSHI. 7 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the gene for the b subunit of human factor XIII."
      Bottenus R.E., Ichinose A., Davie E.W.
      Biochemistry 29:11195-11209(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT HIS-115.
    2. "Amino acid sequence of the b subunit of human factor XIII, a protein composed of ten repetitive segments."
      Ichinose A., McMullen B.A., Fujikawa K., Davie E.W.
      Biochemistry 25:4633-4638(1986) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-661, VARIANT HIS-115.
    3. Ichinose A.
      Submitted (FEB-1987) to the EMBL/GenBank/DDBJ databases
      Cited for: SEQUENCE REVISION.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT GLU-569.
      Tissue: Heart.
    5. SeattleSNPs variation discovery resource
      Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS HIS-115; THR-342; ARG-350; PRO-529 AND GLU-569.
    6. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "Complete cDNA sequence encoding the B subunit of human factor XIII."
      Grundmann U., Nerlich C., Rein T., Zettlmeissl G.
      Nucleic Acids Res. 18:2817-2817(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-20.
      Tissue: Liver.
    8. "Truncated mutant B subunit for factor XIII causes its deficiency due to impaired intracellular transportation."
      Koseki S., Souri M., Koga S., Yamakawa M., Shichishima T., Maruyama Y., Yanai F., Ichinose A.
      Blood 97:2667-2672(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: INVOLVEMENT IN FA13BD.
    9. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T., Qian W.-J., Gritsenko M.A., Camp D.G. II, Monroe M.E., Moore R.J., Smith R.D.
      J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-545.
      Tissue: Plasma.
    10. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.
      J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-162.
      Tissue: Liver.
    11. "Two genetic defects in a patient with complete deficiency of the b-subunit for coagulation factor XIII."
      Hashiguchi T., Saito M., Morishita E., Matsuda T., Ichinose A.
      Blood 82:145-150(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: VARIANT FA13BD PHE-450.
    12. Cited for: VARIANTS VAL-49; HIS-115; ARG-350; VAL-388; SER-543 AND GLU-569.

    Entry informationi

    Entry nameiF13B_HUMAN
    AccessioniPrimary (citable) accession number: P05160
    Secondary accession number(s): A8K3E5, Q5VYL5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 13, 1987
    Last sequence update: April 17, 2007
    Last modified: October 1, 2014
    This is version 148 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3