Reviewed, UniProtKB/Swiss-Prot P05116 (ACCO1_SOLLC)

Names and origin

Protein names

Recommended name:
    1-aminocyclopropane-1-carboxylate oxidase 1
      Short name=ACC oxidase 1
    EC=1.14.17.4
Alternative name(s):
    Ethylene-forming enzyme
      Short name=EFE
    Protein pTOM 13

Gene names

Name:	ACO1
Synonyms:	ETH1

Organism

Solanum lycopersicum (Tomato) (Lycopersicon esculentum)

Taxonomic identifier

4081 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length	315 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	1-aminocyclopropane-1-carboxylate + ascorbate + O2 = ethylene + cyanide + dehydroascorbate + CO2 + 2 H2O.
Cofactor	Iron.
Pathway	Alkene biosynthesis; ethylene biosynthesis via S-adenosyl-L-methionine; ethylene from S-adenosyl-L-methionine: step 2/2.
Tissue specificity	Predominantly expressed in the petals and the stigma and style.
Developmental stage	Expressed during fruit ripening.
Sequence similarities	Belongs to the iron/ascorbate-dependent oxidoreductase family.

Ontologies

Keywords
Biological process	Ethylene biosynthesis Fruit ripening
Ligand	Iron Metal-binding Vitamin C
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	ethylene biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW ripening Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	1-aminocyclopropane-1-carboxylate oxidase activity Inferred from electronic annotation. Source: EC L-ascorbic acid binding Inferred from electronic annotation. Source: UniProtKB-KW iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 315	315	1-aminocyclopropane-1-carboxylate oxidase 1		PRO_0000067261
Sites
	Metal binding	177	1	Iron By similarity
	Metal binding	179	1	Iron By similarity
	Metal binding	234	1	Iron By similarity

Sequences

	Sequence		Length	Mass (Da)
	P05116-1 [UniParc]. Last modified July 1, 1993. Version 2. Checksum: 053E975EC8B5B2E9	FASTA	315	35,813
	10 20 30 40 50 60 MENFPIINLE KLNGDERANT MEMIKDACEN WGFFELVNHG IPHEVMDTVE KMTKGHYKKC 70 80 90 100 110 120 MEQRFKELVA SKGLEAVQAE VTDLDWESTF FLRHLPTSNI SQVPDLDEEY REVMRDFAKR 130 140 150 160 170 180 LEKLAEELLD LLCENLGLEK GYLKNAFYGS KGPNFGTKVS NYPPCPKPDL IKGLRAHTDA 190 200 210 220 230 240 GGIILLFQDD KVSGLQLLKD EQWIDVPPMR HSIVVNLGDQ LEVITNGKYK SVLHRVIAQT 250 260 270 280 290 300 DGTRMSLASF YNPGSDAVIY PAKTLVEKEA EESTQVYPKF VFDDYMKLYA GLKFQAKEPR 310 FEAMKAMESD PIASA

References

[1]	"eth1, a gene involved in ethylene synthesis in tomato." Koeck M., Hamilton A.J., Grierson D. Plant Mol. Biol. 17:141-142(1991) [PubMed: 1868215] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Ailsa Craig.
[2]	"Structure and expression of an ethylene-related mRNA from tomato." Holdsworth M.J., Bird C.R., Ray J., Schuch W., Grierson D. Nucleic Acids Res. 15:731-739(1987) [PubMed: 3029690] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 21-315. Strain: cv. Ailsa Craig.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X58273 Genomic DNA. Translation: CAA41212.1. X04792 mRNA. Translation: CAA28479.1.
PIR	S16591.
UniGene	Les.19419
3D structure databases
HSSP	HSSP built from PDB template 1GP6 based on UniProtKB Q96323.
SMR	P05116. Positions 2-307.
ModBase	Search...
Family and domain databases
InterPro	IPR005123. Oxoglutarate/Fe-dep_Oase. [Graphical view]
Pfam	PF03171. 2OG-FeII_Oxy. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACCO1_SOLLC

Accession

Primary (citable) accession number: P05116

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 13, 1987
Last sequence update:	July 1, 1993
Last modified:	May 5, 2009
This is version 67 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)