P05078 (2B_TRVTC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Protein 2b Alternative name(s): 29.1 kDa protein
Organism	Tobacco rattle virus (strain TCM)
Taxonomic identifier	12299 [NCBI]
Taxonomic lineage	Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Virgaviridae › Tobravirus › Tobacco rattle virus
Virus host	Beta vulgaris (Sugar beet) [TaxID: 161934] Capsicum annuum (Bell pepper) [TaxID: 4072] Hyacinthus [TaxID: 82024] Narcissus pseudonarcissus (Daffodil) [TaxID: 39639] Nicotiana tabacum (Common tobacco) [TaxID: 4097] Solanum tuberosum (Potato) [TaxID: 4113] Spinacia oleracea (Spinach) [TaxID: 3562] Stellaria media (Common chickweed) (Alsine media) [TaxID: 13274] Tulipa [TaxID: 13305] Viola arvensis (European field pansy) (Field violet) [TaxID: 97415]

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May function by interacting with a small, flexible domain located at the C-terminus of the CP, forming a bridge between the virus particle and the internal surface of the vector nematode feeding apparatus.
Subcellular location	Virion Ref.2.
Miscellaneous	The genome of this virus consists of two linear, positive, single-stranded RNAs encapsidated in separate virions. They are designated RNA-1 and RNA-2. This protein was translated from the RNA-2.
Sequence similarities	Belongs to the tobravirus protein 2b family.

Ontologies

Keywords
Cellular component	Virion
Gene Ontology (GO)
Biological_process	transmission of virus Inferred from electronic annotation. Source: InterPro
Cellular_component	virion Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	Protein 2b		PRO_0000222515

Sequences

	Sequence		Length	Mass (Da)
	P05078 [UniParc]. Last modified August 13, 1987. Version 1. Checksum: D61FA04867DC132C	FASTA	255	29,018
	10 20 30 40 50 60 MGNGDWSSKW PNDHLFIDDF GKLVWFDVLT DIVKISHFVS QVPTDLSPIP SSYISFIDGR 70 80 90 100 110 120 IPMCINHLGW VYIRVKFESE EVFYQKFGEV DVSRFGESEL PPDFEVTFSK VTTLVNKSLV 130 140 150 160 170 180 RKSELLEKMN NELKQELTNK LDSLEKVNVQ LKKELSQAQQ SNFTELRDGL ILNFSKVGGR 190 200 210 220 230 240 IHRMVVRSIQ NQLKLVSEIN NDGDRWATMG ATVILKEGAQ YLGFVVVKND GKIGVKFDLT 250 RLNSLDNQTL LASVV

References

[1]	"RNA 2 of tobacco rattle virus strain TCM encodes an unexpected gene." Angenent G.C., Linthorst H.J.M., van Belkum A.F., Cornelissen B.J.C., Bol J.F. Nucleic Acids Res. 14:4673-4682(1986) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]	"Immunogold localization of tobravirus 2b nematode transmission helper protein associated with virus particles." Vellios E., Duncan G., Brown D., MacFarlane S. Virology 300:118-124(2002) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION. Strain: Isolate PaY4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X03955 Genomic RNA. Translation: CAA27585.1.
PIR	WMBV2T. A04185.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	P05078.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR007935. Tobravirus_2B. [Graphical view]
Pfam	PF05271. Tobravirus_2B. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

2B_TRVTC

Accession

Primary (citable) accession number: P05078

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 13, 1987
Last sequence update:	August 13, 1987
Last modified:	April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program