Reviewed, UniProtKB/Swiss-Prot P04940 (KV6A6_MOUSE)

Names and origin

Protein names	Recommended name:     Ig kappa chain V-VI region NQ2-17.4.1
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	107 AA.
Sequence status	Complete.
Protein existence	Predicted.

General annotation (Comments)

Function

Anti-2-phenyl oxazolone (PHOX) Antibody.

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain
PTM	Disulfide bond
Technical term	Hybridoma
Gene Ontology (GO)
Molecular function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›107	›107	Ig kappa chain V-VI region NQ2-17.4.1		PRO_0000059815
Regions
	Region	1 – 23	23	Framework-1
	Region	24 – 33	10	Complementarity-determining-1
	Region	34 – 48	15	Framework-2
	Region	49 – 55	7	Complementarity-determining-2
	Region	56 – 87	32	Framework-3
	Region	88 – 96	9	Complementarity-determining-3
	Region	97 – 106	10	Framework-4
Amino acid modifications
	Disulfide bond	23 ↔ 87		By similarity
Experimental info
	Non-terminal residue	107	1

Sequences

	Sequence		Length	Mass (Da)
	P04940-1 [UniParc]. Last modified August 13, 1987. Version 1. Checksum: 6F694284ECFA68E6	FASTA	107	11,561
	10 20 30 40 50 60 QIVLTQSPAI MSASPGQKVT MTCSASSSVS YMHWYQQKSG TSPKRWIYDT SKLASGVPAR 70 80 90 100 FSGSGSATSY SLTITSMQAE DAATYYCQQW SSNPLTFGAG TKLELKR

References

[1]	"mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification." Kaartinen M., Griffiths G.M., Markham A.F., Milstein C. Nature 304:320-324(1983) [PubMed: 6877353] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	K00735 mRNA. Translation: AAA38680.1.
IPI	IPI00462890.
PIR	B49049. PH1084.
3D structure databases
SMR	P04940. Positions 1-107.
ModBase	Search...
Protein family/group databases
IMGT	Search...
Proteomic databases
PRIDE	P04940.
Phylogenomic databases
HOVERGEN	P04940.
Gene expression databases
Genevestigator	P04940.
GermOnline	ENSMUSG00000071393. Mus musculus.
Family and domain databases
InterPro	IPR007110. Ig-like. IPR013783. Ig-like_fold. IPR013106. Ig_V-set. IPR003596. Ig_V-set_sub. [Graphical view]
Gene3D	G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
Pfam	PF07686. V-set. 1 hit. [Graphical view]
SMART	SM00406. IGv. 1 hit. [Graphical view]
PROSITE	PS50835. IG_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KV6A6_MOUSE

Accession

Primary (citable) accession number: P04940

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 13, 1987
Last sequence update:	August 13, 1987
Last modified:	November 24, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)