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P04920

- B3A2_HUMAN

UniProt

P04920 - B3A2_HUMAN

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Protein

Anion exchange protein 2

Gene
SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Plasma membrane anion exchange protein of wide distribution.

GO - Molecular functioni

  1. anion transmembrane transporter activity Source: ProtInc
  2. chloride transmembrane transporter activity Source: Ensembl
  3. inorganic anion exchanger activity Source: InterPro

GO - Biological processi

  1. anion transport Source: ProtInc
  2. bicarbonate transport Source: Reactome
  3. ion transport Source: Reactome
  4. transmembrane transport Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Anion exchange, Antiport, Ion transport, Transport

Enzyme and pathway databases

ReactomeiREACT_19298. Bicarbonate transporters.

Protein family/group databases

TCDBi2.A.31.1.2. the anion exchanger (ae) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Anion exchange protein 2
Short name:
AE 2
Short name:
Anion exchanger 2
Alternative name(s):
Non-erythroid band 3-like protein
Short name:
BND3L
Solute carrier family 4 member 2
Gene namesi
Name:SLC4A2
Synonyms:AE2, EPB3L1, HKB3, MPB3L
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:11028. SLC4A2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 707707Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei708 – 73124Helical; Reviewed predictionAdd
BLAST
Transmembranei737 – 77438Helical; Reviewed predictionAdd
BLAST
Transmembranei784 – 81633Helical; Reviewed predictionAdd
BLAST
Transmembranei826 – 84722Helical; Reviewed predictionAdd
BLAST
Topological domaini848 – 90053Extracellular Reviewed predictionAdd
BLAST
Transmembranei901 – 91818Helical; Reviewed predictionAdd
BLAST
Topological domaini919 – 93315Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei934 – 95421Helical; Reviewed predictionAdd
BLAST
Transmembranei988 – 101023Helical; Reviewed predictionAdd
BLAST
Transmembranei1036 – 105924Helical; Reviewed predictionAdd
BLAST
Transmembranei1091 – 113646Helical; Reviewed predictionAdd
BLAST
Transmembranei1163 – 119937Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. basolateral plasma membrane Source: Ensembl
  2. integral component of membrane Source: UniProtKB-KW
  3. membrane Source: ProtInc
  4. plasma membrane Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35896.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12411241Anion exchange protein 2PRO_0000079215Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei113 – 1131Phosphoserine1 Publication
Modified residuei132 – 1321Phosphoserine1 Publication
Modified residuei144 – 1441Phosphoserine1 Publication
Modified residuei170 – 1701Phosphoserine By similarity
Modified residuei172 – 1721Phosphoserine By similarity
Modified residuei173 – 1731Phosphoserine1 Publication
Modified residuei183 – 1831Phosphothreonine1 Publication
Modified residuei257 – 2571Phosphothreonine By similarity
Modified residuei443 – 4431Phosphoserine1 Publication
Glycosylationi859 – 8591N-linked (GlcNAc...) Reviewed prediction
Glycosylationi868 – 8681N-linked (GlcNAc...) Reviewed prediction
Glycosylationi882 – 8821N-linked (GlcNAc...) Reviewed prediction
Lipidationi1173 – 11731S-palmitoyl cysteine By similarity

Keywords - PTMi

Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein

Proteomic databases

MaxQBiP04920.
PaxDbiP04920.
PeptideAtlasiP04920.
PRIDEiP04920.

PTM databases

PhosphoSiteiP04920.

Expressioni

Gene expression databases

ArrayExpressiP04920.
BgeeiP04920.
CleanExiHS_SLC4A2.
GenevestigatoriP04920.

Organism-specific databases

HPAiHPA019339.

Interactioni

Protein-protein interaction databases

BioGridi112413. 2 interactions.
IntActiP04920. 4 interactions.
STRINGi9606.ENSP00000311402.

Structurei

3D structure databases

ProteinModelPortaliP04920.
SMRiP04920. Positions 322-637, 692-733.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni708 – 1241534Membrane (anion exchange)Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi5 – 320316Pro-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG268067.
HOVERGENiHBG004326.
InParanoidiP04920.
KOiK13855.
OMAiDREMKCL.
OrthoDBiEOG7TMZR0.
PhylomeDBiP04920.
TreeFamiTF313630.

Family and domain databases

Gene3Di3.40.1100.10. 1 hit.
InterProiIPR001717. Anion_exchange.
IPR002978. Anion_exchange_2.
IPR018241. Anion_exchange_CS.
IPR013769. Band3_cytoplasmic_dom.
IPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
IPR016152. PTrfase/Anion_transptr.
[Graphical view]
PANTHERiPTHR11453. PTHR11453. 1 hit.
PTHR11453:SF14. PTHR11453:SF14. 1 hit.
PfamiPF07565. Band_3_cyto. 1 hit.
PF00955. HCO3_cotransp. 1 hit.
[Graphical view]
PRINTSiPR00165. ANIONEXCHNGR.
PR01188. ANIONEXHNGR2.
PR01231. HCO3TRNSPORT.
SUPFAMiSSF55804. SSF55804. 2 hits.
TIGRFAMsiTIGR00834. ae. 1 hit.
PROSITEiPS00219. ANION_EXCHANGER_1. 1 hit.
PS00220. ANION_EXCHANGER_2. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Note: Additional isoforms seem to exist.

Isoform A (identifier: P04920-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSSAPRRPAK GADSFCTPEP ESLGPGTPGF PEQEEDELHR TLGVERFEEI     50
LQEAGSRGGE EPGRSYGEED FEYHRQSSHH IHHPLSTHLP PDARRRKTPQ 100
GPGRKPRRRP GASPTGETPT IEEGEEDEDE ASEAEGARAL TQPSPVSTPS 150
SVQFFLQEDD SADRKAERTS PSSPAPLPHQ EATPRASKGA QAGTQVEEAE 200
AEAVAVASGT AGGDDGGASG RPLPKAQPGH RSYNLQERRR IGSMTGAEQA 250
LLPRVPTDEI EAQTLATADL DLMKSHRFED VPGVRRHLVR KNAKGSTQSG 300
REGREPGPTP RARPRAPHKP HEVFVELNEL LLDKNQEPQW RETARWIKFE 350
EDVEEETERW GKPHVASLSF RSLLELRRTL AHGAVLLDLD QQTLPGVAHQ 400
VVEQMVISDQ IKAEDRANVL RALLLKHSHP SDEKDFSFPR NISAGSLGSL 450
LGHHHGQGAE SDPHVTEPLM GGVPETRLEV ERERELPPPA PPAGITRSKS 500
KHELKLLEKI PENAEATVVL VGCVEFLSRP TMAFVRLREA VELDAVLEVP 550
VPVRFLFLLL GPSSANMDYH EIGRSISTLM SDKQFHEAAY LADEREDLLT 600
AINAFLDCSV VLPPSEVQGE ELLRSVAHFQ RQMLKKREEQ GRLLPTGAGL 650
EPKSAQDKAL LQMVEAAGAA EDDPLRRTGR PFGGLIRDVR RRYPHYLSDF 700
RDALDPQCLA AVIFIYFAAL SPAITFGGLL GEKTQDLIGV SELIMSTALQ 750
GVVFCLLGAQ PLLVIGFSGP LLVFEEAFFS FCSSNHLEYL VGRVWIGFWL 800
VFLALLMVAL EGSFLVRFVS RFTQEIFAFL ISLIFIYETF YKLVKIFQEH 850
PLHGCSASNS SEVDGGENMT WAGARPTLGP GNRSLAGQSG QGKPRGQPNT 900
ALLSLVLMAG TFFIAFFLRK FKNSRFFPGR IRRVIGDFGV PIAILIMVLV 950
DYSIEDTYTQ KLSVPSGFSV TAPEKRGWVI NPLGEKSPFP VWMMVASLLP 1000
AILVFILIFM ETQITTLIIS KKERMLQKGS GFHLDLLLIV AMGGICALFG 1050
LPWLAAATVR SVTHANALTV MSKAVAPGDK PKIQEVKEQR VTGLLVALLV 1100
GLSIVIGDLL RQIPLAVLFG IFLYMGVTSL NGIQFYERLH LLLMPPKHHP 1150
DVTYVKKVRT LRMHLFTALQ LLCLALLWAV MSTAASLAFP FILILTVPLR 1200
MVVLTRIFTD REMKCLDANE AEPVFDEREG VDEYNEMPMP V 1241
Length:1,241
Mass (Da):137,009
Last modified:January 24, 2006 - v4
Checksum:i35E32D9FC34DFB61
GO
Isoform B1 (identifier: P04920-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: MSSAPRRPAKGADSFCT → MTQ

Show »
Length:1,227
Mass (Da):135,606
Checksum:iBA59FBFDF46178F2
GO
Isoform 3 (identifier: P04920-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: MSSAPRRPAKGADSFCT → MDFLLRPQ

Note: No experimental confirmation available.

Show »
Length:1,232
Mass (Da):136,247
Checksum:iC57606D7CA9D34D2
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti26 – 261G → E.1 Publication
Corresponds to variant rs2303929 [ dbSNP | Ensembl ].
VAR_025168
Natural varianti202 – 2021E → V.1 Publication
Corresponds to variant rs2229551 [ dbSNP | Ensembl ].
VAR_025169
Natural varianti208 – 2081S → T.
Corresponds to variant rs2229552 [ dbSNP | Ensembl ].
VAR_048349
Natural varianti311 – 3111R → W.1 Publication
Corresponds to variant rs35016052 [ dbSNP | Ensembl ].
VAR_025170
Natural varianti1204 – 12041L → F.1 Publication
Corresponds to variant rs34918764 [ dbSNP | Ensembl ].
VAR_025171

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 1717MSSAP…DSFCT → MDFLLRPQ in isoform 3. VSP_045953Add
BLAST
Alternative sequencei1 – 1717MSSAP…DSFCT → MTQ in isoform B1. VSP_000456Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti7 – 71R → L in CAA44067. 1 Publication
Sequence conflicti68 – 681E → M in CAA44067. 1 Publication
Sequence conflicti74 – 741H → R in CAA44067. 1 Publication
Sequence conflicti92 – 921D → G in CAA44067. 1 Publication
Sequence conflicti122 – 1221E → V in CAA44067. 1 Publication
Sequence conflicti157 – 1571Q → R in CAA44067. 1 Publication
Sequence conflicti248 – 2481E → R in CAA44067. 1 Publication
Sequence conflicti399 – 3991Missing in CAA27556. 1 Publication
Sequence conflicti447 – 4471L → V in CAA44067. 1 Publication
Sequence conflicti450 – 47526LLGHH…GGVPE → CWGITMVRGLRVTPTSPSLS WEVFLR in CAA27556. 1 PublicationAdd
BLAST
Sequence conflicti485 – 4862EL → DV in CAA44067. 1 Publication
Sequence conflicti485 – 4862EL → DV in CAA27556. 1 Publication
Sequence conflicti571 – 5711E → K in BAG58592. 1 Publication
Sequence conflicti666 – 68116AAGAA…RTGRP → RQGQLKMIPSADGAA in CAA44067. 1 PublicationAdd
BLAST
Sequence conflicti666 – 68116AAGAA…RTGRP → RQGQLKMIPSADGAA in CAA27556. 1 PublicationAdd
BLAST
Sequence conflicti824 – 8241Q → R in CAA44067. 1 Publication
Sequence conflicti824 – 8241Q → R in CAA27556. 1 Publication
Sequence conflicti902 – 9021L → P in CAA44067. 1 Publication
Sequence conflicti902 – 9021L → P in CAA27556. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X62137 mRNA. Translation: CAA44067.1.
DQ149844 Genomic DNA. Translation: AAZ38724.1.
AK295767 mRNA. Translation: BAG58592.1.
AK312699 mRNA. Translation: BAG35577.1.
AC010973 Genomic DNA. No translation available.
CH471173 Genomic DNA. Translation: EAW54046.1.
CH471173 Genomic DNA. Translation: EAW54047.1.
BC009386 mRNA. Translation: AAH09386.1.
BC009434 mRNA. Translation: AAH09434.1.
X03918 mRNA. Translation: CAA27556.1.
CCDSiCCDS56520.1. [P04920-3]
CCDS56521.1. [P04920-2]
CCDS5917.1. [P04920-1]
PIRiS21086.
RefSeqiNP_001186621.1. NM_001199692.1. [P04920-1]
NP_001186622.1. NM_001199693.1. [P04920-3]
NP_001186623.1. NM_001199694.1. [P04920-2]
NP_003031.3. NM_003040.3. [P04920-1]
UniGeneiHs.647069.

Genome annotation databases

EnsembliENST00000392826; ENSP00000376571; ENSG00000164889. [P04920-3]
ENST00000413384; ENSP00000405600; ENSG00000164889. [P04920-1]
ENST00000461735; ENSP00000419164; ENSG00000164889. [P04920-2]
ENST00000485713; ENSP00000419412; ENSG00000164889. [P04920-1]
GeneIDi6522.
KEGGihsa:6522.
UCSCiuc003wit.4. human. [P04920-1]
uc003wiu.4. human. [P04920-2]

Polymorphism databases

DMDMi85687559.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

NIEHS-SNPs

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X62137 mRNA. Translation: CAA44067.1 .
DQ149844 Genomic DNA. Translation: AAZ38724.1 .
AK295767 mRNA. Translation: BAG58592.1 .
AK312699 mRNA. Translation: BAG35577.1 .
AC010973 Genomic DNA. No translation available.
CH471173 Genomic DNA. Translation: EAW54046.1 .
CH471173 Genomic DNA. Translation: EAW54047.1 .
BC009386 mRNA. Translation: AAH09386.1 .
BC009434 mRNA. Translation: AAH09434.1 .
X03918 mRNA. Translation: CAA27556.1 .
CCDSi CCDS56520.1. [P04920-3 ]
CCDS56521.1. [P04920-2 ]
CCDS5917.1. [P04920-1 ]
PIRi S21086.
RefSeqi NP_001186621.1. NM_001199692.1. [P04920-1 ]
NP_001186622.1. NM_001199693.1. [P04920-3 ]
NP_001186623.1. NM_001199694.1. [P04920-2 ]
NP_003031.3. NM_003040.3. [P04920-1 ]
UniGenei Hs.647069.

3D structure databases

ProteinModelPortali P04920.
SMRi P04920. Positions 322-637, 692-733.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 112413. 2 interactions.
IntActi P04920. 4 interactions.
STRINGi 9606.ENSP00000311402.

Protein family/group databases

TCDBi 2.A.31.1.2. the anion exchanger (ae) family.

PTM databases

PhosphoSitei P04920.

Polymorphism databases

DMDMi 85687559.

Proteomic databases

MaxQBi P04920.
PaxDbi P04920.
PeptideAtlasi P04920.
PRIDEi P04920.

Protocols and materials databases

DNASUi 6522.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000392826 ; ENSP00000376571 ; ENSG00000164889 . [P04920-3 ]
ENST00000413384 ; ENSP00000405600 ; ENSG00000164889 . [P04920-1 ]
ENST00000461735 ; ENSP00000419164 ; ENSG00000164889 . [P04920-2 ]
ENST00000485713 ; ENSP00000419412 ; ENSG00000164889 . [P04920-1 ]
GeneIDi 6522.
KEGGi hsa:6522.
UCSCi uc003wit.4. human. [P04920-1 ]
uc003wiu.4. human. [P04920-2 ]

Organism-specific databases

CTDi 6522.
GeneCardsi GC07P150754.
HGNCi HGNC:11028. SLC4A2.
HPAi HPA019339.
MIMi 109280. gene.
neXtProti NX_P04920.
PharmGKBi PA35896.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG268067.
HOVERGENi HBG004326.
InParanoidi P04920.
KOi K13855.
OMAi DREMKCL.
OrthoDBi EOG7TMZR0.
PhylomeDBi P04920.
TreeFami TF313630.

Enzyme and pathway databases

Reactomei REACT_19298. Bicarbonate transporters.

Miscellaneous databases

ChiTaRSi SLC4A2. human.
GeneWikii SLC4A2.
GenomeRNAii 6522.
NextBioi 25371.
PROi P04920.
SOURCEi Search...

Gene expression databases

ArrayExpressi P04920.
Bgeei P04920.
CleanExi HS_SLC4A2.
Genevestigatori P04920.

Family and domain databases

Gene3Di 3.40.1100.10. 1 hit.
InterProi IPR001717. Anion_exchange.
IPR002978. Anion_exchange_2.
IPR018241. Anion_exchange_CS.
IPR013769. Band3_cytoplasmic_dom.
IPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
IPR016152. PTrfase/Anion_transptr.
[Graphical view ]
PANTHERi PTHR11453. PTHR11453. 1 hit.
PTHR11453:SF14. PTHR11453:SF14. 1 hit.
Pfami PF07565. Band_3_cyto. 1 hit.
PF00955. HCO3_cotransp. 1 hit.
[Graphical view ]
PRINTSi PR00165. ANIONEXCHNGR.
PR01188. ANIONEXHNGR2.
PR01231. HCO3TRNSPORT.
SUPFAMi SSF55804. SSF55804. 2 hits.
TIGRFAMsi TIGR00834. ae. 1 hit.
PROSITEi PS00219. ANION_EXCHANGER_1. 1 hit.
PS00220. ANION_EXCHANGER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete nucleotide sequence of band 3 related anion transport protein AE2 from human kidney."
    Gehrig H., Mueller W., Appelhans H.
    Biochim. Biophys. Acta 1130:326-328(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A).
  2. NIEHS SNPs program
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS GLU-26; VAL-202; TRP-311 AND PHE-1204.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A AND 3).
    Tissue: Hippocampus.
  4. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B1).
    Tissue: Brain.
  7. "Cloning and structural characterization of a human non-erythroid band 3-like protein."
    Demuth D.R., Showe L.C., Ballantine M., Palumbo A., Fraser P.J., Cioe L., Rovera G., Curtis P.J.
    EMBO J. 5:1205-1214(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 375-1241.
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113; SER-132; SER-173 AND THR-183, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-144, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-443, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiB3A2_HUMAN
AccessioniPrimary (citable) accession number: P04920
Secondary accession number(s): B2R6T0
, B4DIT0, D3DX05, F8W682, Q45EY5, Q969L3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: January 24, 2006
Last modified: September 3, 2014
This is version 158 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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