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P04907 (GSTF3_MAIZE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase 3

EC=2.5.1.18
Alternative name(s):
GST class-phi member 3
GST-III
Gene names
Name:GST3
OrganismZea mays (Maize)
Taxonomic identifier4577 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Protein attributes

Sequence length222 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the detoxification of certain herbicides.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subunit structure

Homodimer.

Sequence similarities

Belongs to the GST superfamily. Phi family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Molecular functionTransferase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed
Chain2 – 222221Glutathione S-transferase 3
PRO_0000185842

Regions

Domain2 – 8382GST N-terminal
Domain89 – 219131GST C-terminal
Region41 – 422Glutathione binding By similarity
Region54 – 552Glutathione binding By similarity
Region67 – 682Glutathione binding By similarity

Sites

Binding site121Glutathione By similarity

Experimental info

Sequence conflict1081H → Y Ref.2
Sequence conflict111 – 12717ASPLV…LLGGA → RVAAGVPAAREAAPGRR in CAA27957. Ref.2
Sequence conflict111 – 12717ASPLV…LLGGA → RVAAGVPAAREAAPGRR in CAA28053. Ref.2
Sequence conflict1341E → D in CAA27957. Ref.2
Sequence conflict1341E → D in CAA28053. Ref.2
Sequence conflict149 – 18032AHLAR…TSARP → RTSPATSTSPGTSSRSPTPT TRSYLLYLSKT in CAA27957. Ref.2
Sequence conflict184 – 1896GCVAAR → ARRRP in CAA27957. Ref.2
Sequence conflict2001A → V in CAA27957. Ref.2
Sequence conflict2001A → V in CAA28053. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P04907 [UniParc].

Last modified January 23, 2007. Version 4.
Checksum: 4CB77A3B1B6E3C46

FASTA22223,849
        10         20         30         40         50         60 
MAPLKLYGMP LSPNVVRVAT VLNEKGLDFE IVPVDLTTGA HKQPDFLALN PFGQIPALVD 

        70         80         90        100        110        120 
GDEVLFESRA INRYIASKYA SEGTDLLPAT ASAAKLEVWL EVESHHFHPN ASPLVFQLLV 

       130        140        150        160        170        180 
RPLLGGAPDA AVVEKHAEQL AKVLDVYEAH LARNKYLAGD EFTLADANHA LLPALTSARP 

       190        200        210        220 
PRPGCVAARP HVKAWWEAIA ARPAFQKTVA AIPLPPPPSS SA 

« Hide

References

[1]"Characterization and heterospecific expression of cDNA clones of genes in the maize GSH S-transferase multigene family."
Grove G., Zarlengo R.P., Timmerman K.P., Li N.-Q., Tam M.F., Tu C.-P.D.
Nucleic Acids Res. 16:425-438(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Cloning and expression of a cDNA encoding a maize glutathione-S-transferase in E. coli."
Moore R.E., Davies M.S., O'Connell K.M., Harding E.I., Wiegand R.C., Tiemeier D.C.
Nucleic Acids Res. 14:7227-7235(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]"The maize two dimensional gel protein database: towards an integrated genome analysis program."
Touzet P., Riccardi F., Morin C., Damerval C., Huet J.-C., Pernollet J.-C., Zivy M., de Vienne D.
Theor. Appl. Genet. 93:997-1005(1996) [AGRICOLA] [Europe PMC]
Cited for: PROTEIN SEQUENCE OF 143-153.
Tissue: Coleoptile.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X06755 mRNA. Translation: CAA29929.1.
X04375 mRNA. Translation: CAA27957.1.
X04455 mRNA. Translation: CAA28053.1.
PIRXUZM31. A24703.
XUZM32. S00717.
RefSeqNP_001106075.1. NM_001112605.1.
UniGeneZm.103382.

3D structure databases

ProteinModelPortalP04907.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP04907.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100127012.
KEGGzma:100127012.

Organism-specific databases

GrameneP04907.
MaizeGDB65344.

Phylogenomic databases

HOGENOMHOG000125746.
KOK00799.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTF3_MAIZE
AccessionPrimary (citable) accession number: P04907
Secondary accession number(s): P15542
Entry history
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 90 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families