P04874 (NSS_BUNLC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Non-structural protein NS-S

Gene names

Name:

N

Organism

Bunyavirus La Crosse

Taxonomic identifier

11577 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Bunyaviridae › Orthobunyavirus › California encephalitis virus

Virus host

Aedes triseriatus (Eastern treehole mosquito) (Ochlerotatus triseriatus) [TaxID: 7162]
Cervidae (deer) [TaxID: 9850]
Homo sapiens (Human) [TaxID: 9606]
Tamias [TaxID: 13712]

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the orthobunyavirus NS-S protein family.

Ontologies

Keywords
Coding sequence diversity	Alternative initiation
Gene Ontology (GO)
Biological_process	viral reproduction Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative initiation. [Align] [Select]

Isoform NSS (identifier: P04874-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: Produced by alternative initiation in the N gene, but encoded on another frame.

Isoform N (identifier: P04873-1)

The sequence of this isoform can be found in the external entry P04873.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	Non-structural protein NS-S		PRO_0000221973
Experimental info
	Sequence conflict	40	1	P → L in AAA42780. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform NSS [UniParc]. Last modified August 13, 1987. Version 1. Checksum: 03572181F26C6348	FASTA	92	10,441
	10 20 30 40 50 60 MMSHQQVQMD LILMQGIWTS VLKMQNHSTL LQLGSSSSMP QRPRLLSRVS QRGRLTLNLE 70 80 90 SGRWRLSIII FLETGTTQLV TTILPSTDYL GI
	Isoform N [UniParc]. See P04873.		–	–

References

[1]	"Comparison of the sequences and coding of La Crosse and snowshoe hare bunyavirus S RNA species." Akashi H., Bishop D.H.L. J. Virol. 45:1155-1158(1983) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]	"Molecular cloning and sequencing of the La Crosse virus S RNA." Cabradilla C.D. Jr., Holloway B.P., Obijeski J.F. Virology 128:463-468(1983) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	K00610 Genomic RNA. Translation: AAA42783.1. K00108 Genomic RNA. Translation: AAA42780.1.
PIR	MNVULV. A04106.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000797. Bunya_NSs. [Graphical view]
Pfam	PF01104. Bunya_NS-S. 1 hit. [Graphical view]
PIRSF	PIRSF003954. NS-S_OrthobunV. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NSS_BUNLC

Accession

Primary (citable) accession number: P04874

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 13, 1987
Last sequence update:	August 13, 1987
Last modified:	April 3, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program