P04873 (NCAP_BUNLC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nucleoprotein

Alternative name(s):
Nucleocapsid protein
Short name=Protein N

Gene names

Name:

N

Organism

Bunyavirus La Crosse

Taxonomic identifier

11577 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Bunyaviridae › Orthobunyavirus › California encephalitis virus

Virus host

Aedes triseriatus (Eastern treehole mosquito) (Ochlerotatus triseriatus) [TaxID: 7162]
Cervidae (deer) [TaxID: 9850]
Homo sapiens (Human) [TaxID: 9606]
Tamias [TaxID: 13712]

Protein attributes

Sequence length	235 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Virion. Note: Internal protein of virus particle.
Sequence similarities	Belongs to the orthobunyavirus nucleocapsid protein family.

Ontologies

Keywords
Cellular component	Virion
Coding sequence diversity	Alternative initiation
Ligand	RNA-binding Viral nucleoprotein
Molecular function	Ribonucleoprotein
Gene Ontology (GO)
Cellular_component	ribonucleoprotein complex Inferred from electronic annotation. Source: UniProtKB-KW viral nucleocapsid Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative initiation. [Align] [Select]

Isoform N (identifier: P04873-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform NSS (identifier: P04874-1)

The sequence of this isoform can be found in the external entry P04874.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Note: Produced by alternative initiation in the N gene, but encoded on another frame.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 235	235	Nucleoprotein		PRO_0000221990

Sequences

	Sequence		Length	Mass (Da)
	Isoform N [UniParc]. Last modified August 13, 1987. Version 1. Checksum: 56EBB4D64AD04A96	FASTA	235	26,530
	10 20 30 40 50 60 MSDLVFYDVA STGANGFDPD AGYMDFCVKN AESLNLAAVR IFFLNAAKAK AALSRKPERK 70 80 90 100 110 120 ANPKFGEWQV EVINNHFPGN RNNPIGNNDL TIHRLSGYLA RWVLDQYNEN DDESQHELIR 130 140 150 160 170 180 TTIINPIAES NGVGWDSGPE IYLSFFPGTE MFLETFKFYP LTIGIHRVKQ GMMDPQYLKK 190 200 210 220 230 ALRQRYGTLT ADKWMSQKVA AIAKSLKDVE QLKWGKGGLS DTAKTFLQKF GIRLP
	Isoform NSS [UniParc]. See P04874.		–	–

References

[1]	"Comparison of the sequences and coding of La Crosse and snowshoe hare bunyavirus S RNA species." Akashi H., Bishop D.H.L. J. Virol. 45:1155-1158(1983) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]	"Molecular cloning and sequencing of the La Crosse virus S RNA." Cabradilla C.D. Jr., Holloway B.P., Obijeski J.F. Virology 128:463-468(1983) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	K00610 Genomic RNA. Translation: AAA42782.1. K00108 Genomic RNA. Translation: AAA42779.1.
PIR	VHVULV. A04104.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001784. Bunya_nucleocap. [Graphical view]
Pfam	PF00952. Bunya_nucleocap. 1 hit. [Graphical view]
PIRSF	PIRSF003947. N_OrthobunV. 1 hit.
ProDom	PD001909. Bunya_nucleocap. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

NCAP_BUNLC

Accession

Primary (citable) accession number: P04873

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 13, 1987
Last sequence update:	August 13, 1987
Last modified:	April 3, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program