Skip Header

Contribute Send feedback
Read comments (?) or add your own

P04842 (ALOX_PICPA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alcohol oxidase

Short name=AOX
EC=1.1.3.13
Alternative name(s):
Methanol oxidase
Short name=MOX
OrganismKomagataella pastoris (Yeast) (Pichia pastoris)
Taxonomic identifier4922 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella

Protein attributes

Sequence length33 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

A primary alcohol + O2 = an aldehyde + H2O2.

Cofactor

FAD.

Pathway

Energy metabolism; methane degradation.

Subunit structure

Homooctamer.

Subcellular location

Peroxisome.

Sequence similarities

Belongs to the GMC oxidoreductase family.

Ontologies

Keywords
   Biological processMethanol utilization
   Cellular componentPeroxisome
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processmethane catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

methanol metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentperoxisome

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionalcohol oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›33›33Alcohol oxidase
PRO_0000205582

Regions

Nucleotide binding8 – ›33›26FAD Probable

Experimental info

Non-terminal residue331

Sequences

Sequence LengthMass (Da)Tools
P04842 [UniParc].

Last modified August 13, 1987. Version 1.
Checksum: 9C747B94793FE5CB

FASTA333,372
        10         20         30 
MAIPEEFDIL VLGGGSSGSC IAGRLANLDH SLK 

« Hide

References

[1]"Isolation of alcohol oxidase and two other methanol regulatable genes from the yeast Pichia pastoris."
Ellis S.B., Brust P.F., Koutz P.J., Waters A.F., Harpold M.M., Gingeras T.R.
Mol. Cell. Biol. 5:1111-1121(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Biosynthesis and assembly of alcohol oxidase, a peroxisomal matrix protein in methylotrophic yeasts: a review."
van der Klei I.J., Harder W., Veenhuis M.
Yeast 7:195-209(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: REVIEW.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X02646 Genomic DNA. Translation: CAA26484.1.
PIRA23483.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00147.

Family and domain databases

PROSITEPS00623. GMC_OXRED_1. Partial match.
PS00624. GMC_OXRED_2. Partial match.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALOX_PICPA
AccessionPrimary (citable) accession number: P04842
Entry history
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 13, 1987
Last modified: April 3, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families