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Protein

ADP,ATP carrier protein 1, mitochondrial

Gene

ANT1

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.

Miscellaneous

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. At least 2 of the odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei160NucleotideBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 1, mitochondrial
Alternative name(s):
ADP/ATP translocase 1
Adenine nucleotide translocator 1
Short name:
ANT 1
Gene namesi
Name:ANT1
Synonyms:ANT-G1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Chromosome 5

Organism-specific databases

MaizeGDBi17145.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei84 – 118Helical; Name=1By similarityAdd BLAST35
Transmembranei155 – 179Helical; Name=2By similarityAdd BLAST25
Transmembranei188 – 222Helical; Name=3By similarityAdd BLAST35
Transmembranei257 – 284Helical; Name=4By similarityAdd BLAST28
Transmembranei289 – 323Helical; Name=5By similarityAdd BLAST35
Transmembranei352 – 377Helical; Name=6By similarityAdd BLAST26

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 77MitochondrionSequence analysisAdd BLAST77
ChainiPRO_000001924878 – 387ADP,ATP carrier protein 1, mitochondrialAdd BLAST310

Proteomic databases

PaxDbiP04709.
PRIDEiP04709.

Expressioni

Gene expression databases

ExpressionAtlasiP04709. baseline and differential.

Interactioni

Subunit structurei

Homodimer.

Structurei

3D structure databases

ProteinModelPortaliP04709.
SMRiP04709.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati85 – 178Solcar 1Add BLAST94
Repeati190 – 282Solcar 2Add BLAST93
Repeati290 – 376Solcar 3Add BLAST87

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi317 – 322Substrate recognitionBy similarity6

Sequence similaritiesi

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
HOGENOMiHOG000165727.
KOiK05863.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom_sf.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P04709-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADQANQPTV LHKLGGQFHL RSIISEGVRA RNICPSVSSY ERRFATRNYM
60 70 80 90 100
TQSLWGPSMS VSGGINVPVM QTPLCANAPA EKGGKNFMID FMMGGVSAAV
110 120 130 140 150
SKTAAAPIER VKLLIQNQDE MIKSGRLSEP YKGIVDCFKR TIKDEGFSSL
160 170 180 190 200
WRGNTANVIR YFPTQALNFA FKDYFKRLFN FKKDRDGYWK WFAGNLASGG
210 220 230 240 250
AAGASSLFFV YSLDYARTRL ANDAKAAKGG GERQFNGLVD VYRKTLKSDG
260 270 280 290 300
IAGLYRGFNI SCVGIIVYRG LYFGLYDSIK PVVLTGNLQD NFFASFALGW
310 320 330 340 350
LITNGAGLAS YPIDTVRRRM MMTSGEAVKY KSSLDAFQQI LKKEGPKSLF
360 370 380
KGAGANILRA IAGAGVLSGY DQLQILFFGK KYGSGGA
Length:387
Mass (Da):42,392
Last modified:August 1, 1992 - v3
Checksum:iDE73BB0F478BD57D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti102K → E in CAA33742 (PubMed:2547608).Curated1
Sequence conflicti154N → Y in CAA26600 (PubMed:2994015).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57556 mRNA. Translation: CAA40781.1.
X15711 Genomic DNA. Translation: CAA33742.1.
X02842 mRNA. Translation: CAA26600.1.
PIRiS14876.
RefSeqiNP_001105431.1. NM_001111961.1.
UniGeneiZm.729.

Genome annotation databases

EnsemblPlantsiZm00001d017857_T001; Zm00001d017857_P001; Zm00001d017857.
Zm00001d017857_T004; Zm00001d017857_P004; Zm00001d017857.
GeneIDi542386.
GrameneiZm00001d017857_T001; Zm00001d017857_P001; Zm00001d017857.
Zm00001d017857_T004; Zm00001d017857_P004; Zm00001d017857.
KEGGizma:542386.

Similar proteinsi

Entry informationi

Entry nameiADT1_MAIZE
AccessioniPrimary (citable) accession number: P04709
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 1, 1992
Last modified: November 22, 2017
This is version 125 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families