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P04650 (RL39_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 110. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L39
Alternative name(s):
L46
YL40
Gene names
Name:RPL39
Synonyms:RPL46, SPB2
Ordered Locus Names:YJL189W
ORF Names:J0360
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length51 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.4

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00629.

Sequence similarities

Belongs to the ribosomal protein L39e family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.5
Chain2 – 515060S ribosomal protein L39 HAMAP-Rule MF_00629
PRO_0000127044

Sequences

Sequence LengthMass (Da)Tools
P04650 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: FE518D8B3949C163

FASTA516,342
        10         20         30         40         50 
MAAQKSFRIK QKMAKAKKQN RPLPQWIRLR TNNTIRYNAK RRNWRRTKMN I 

« Hide

References

« Hide 'large scale' references
[1]"The genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed."
Leer R.J., van Raamsdonk-Duin M.M.C., Kraakman P., Mager W.H., Planta R.J.
Nucleic Acids Res. 13:701-709(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
Planta R.J., Mager W.H.
Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE, SUBUNIT.
[5]"The action of N-terminal acetyltransferases on yeast ribosomal proteins."
Arnold R.J., Polevoda B., Reilly J.P., Sherman F.
J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: CLEAVAGE OF INITIATOR METHIONINE.
[6]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]"Crystal structure of the eukaryotic ribosome."
Ben-Shem A., Jenner L., Yusupova G., Yusupov M.
Science 330:1203-1209(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
[8]"The structure of the eukaryotic ribosome at 3.0 A resolution."
Ben-Shem A., Garreau de Loubresse N., Melnikov S., Jenner L., Yusupova G., Yusupov M.
Science 334:1524-1529(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X01963 Genomic DNA. Translation: CAA25999.1.
Z49464 Genomic DNA. Translation: CAA89483.1.
BK006943 Genomic DNA. Translation: DAA08618.1.
PIRR6BY46. B23082.
RefSeqNP_012346.1. NM_001181622.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2WW9electron microscopy8.60O1-51[»]
2WWAelectron microscopy8.90O1-51[»]
3IZSelectron microscopy-o1-51[»]
3O58X-ray4.00e1-51[»]
3O5HX-ray4.00e1-51[»]
3U5EX-ray3.00l1-51[»]
3U5IX-ray3.00l1-51[»]
4B6Aelectron microscopy8.10l1-51[»]
4BYNelectron microscopy4.30l2-51[»]
4BYUelectron microscopy6.60l2-51[»]
ProteinModelPortalP04650.
SMRP04650. Positions 2-51.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33574. 24 interactions.
DIPDIP-4522N.
IntActP04650. 8 interactions.
MINTMINT-8285272.
STRING4932.YJL189W.

Proteomic databases

PaxDbP04650.
PeptideAtlasP04650.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL189W; YJL189W; YJL189W.
GeneID853250.
KEGGsce:YJL189W.

Organism-specific databases

SGDS000003725. RPL39.

Phylogenomic databases

eggNOGCOG2167.
GeneTreeENSGT00390000014814.
HOGENOMHOG000230627.
KOK02924.
OrthoDBEOG7HMSDR.

Enzyme and pathway databases

BioCycYEAST:G3O-31621-MONOMER.

Gene expression databases

GenevestigatorP04650.

Family and domain databases

Gene3D1.10.1620.10. 1 hit.
HAMAPMF_00629. Ribosomal_L39e.
InterProIPR000077. Ribosomal_L39.
IPR020083. Ribosomal_L39_CS.
IPR023626. Ribosomal_L39e_dom.
[Graphical view]
PANTHERPTHR19970. PTHR19970. 1 hit.
PfamPF00832. Ribosomal_L39. 1 hit.
[Graphical view]
SUPFAMSSF48662. SSF48662. 1 hit.
PROSITEPS00051. RIBOSOMAL_L39E. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP04650.
NextBio973493.
PROP04650.

Entry information

Entry nameRL39_YEAST
AccessionPrimary (citable) accession number: P04650
Secondary accession number(s): D6VW02
Entry history
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 110 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references