Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sarcoplasmic calcium-binding protein

Gene
N/A
Organism
Hediste diversicolor (Sandworm) (Nereis diversicolor)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Like parvalbumins, SCP's seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi16 – 27121Add
BLAST
Calcium bindingi104 – 115122Add
BLAST
Calcium bindingi138 – 149123Add
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Muscle protein

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Sarcoplasmic calcium-binding protein
Short name:
SCP
OrganismiHediste diversicolor (Sandworm) (Nereis diversicolor)
Taxonomic identifieri126592 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaPalpataAciculataPhyllodocidaNereididaeHedisteHediste diversicolor species group

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 174174Sarcoplasmic calcium-binding proteinPRO_0000073628Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylserine

Keywords - PTMi

Acetylation

Structurei

Secondary structure

1
174
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi2 – 1514Combined sources
Beta strandi20 – 234Combined sources
Helixi25 – 3814Combined sources
Helixi45 – 5915Combined sources
Helixi61 – 633Combined sources
Turni64 – 674Combined sources
Helixi72 – 8211Combined sources
Helixi86 – 894Combined sources
Helixi90 – 934Combined sources
Helixi95 – 1039Combined sources
Beta strandi108 – 1125Combined sources
Helixi113 – 12210Combined sources
Helixi127 – 1293Combined sources
Helixi130 – 1378Combined sources
Beta strandi142 – 1454Combined sources
Helixi147 – 15913Combined sources
Helixi165 – 1684Combined sources
Beta strandi169 – 1724Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Q80NMR-A1-174[»]
2SCPX-ray2.00A/B1-174[»]
ProteinModelPortaliP04571.
SMRiP04571. Positions 1-174.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP04571.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 3836EF-hand 1PROSITE-ProRule annotationAdd
BLAST
Domaini55 – 9036EF-hand 2PROSITE-ProRule annotationAdd
BLAST
Domaini91 – 12636EF-hand 3PROSITE-ProRule annotationAdd
BLAST
Domaini127 – 16034EF-hand 4PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 4 EF-hand domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13202. EF-hand_5. 3 hits.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P04571-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SDLWVQKMKT YFNRIDFDKD GAITRMDFES MAERFAKESE MKAEHAKVLM
60 70 80 90 100
DSLTGVWDNF LTAVAGGKGI DETTFINSMK EMVKNPEAKS VVEGPLPLFF
110 120 130 140 150
RAVDTNEDNN ISRDEYGIFF GMLGLDKTMA PASFDAIDTN NDGLLSLEEF
160 170
VIAGSDFFMN DGDSTNKVFW GPLV
Length:174
Mass (Da):19,486
Last modified:August 13, 1987 - v1
Checksum:i9569B2FD57AC449B
GO

Sequence databases

PIRiA31989.

Cross-referencesi

Sequence databases

PIRiA31989.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Q80NMR-A1-174[»]
2SCPX-ray2.00A/B1-174[»]
ProteinModelPortaliP04571.
SMRiP04571. Positions 1-174.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP04571.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13202. EF-hand_5. 3 hits.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSCP_HEDDI
AccessioniPrimary (citable) accession number: P04571
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 13, 1987
Last modified: December 9, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Miscellaneous

The sarcoplasmic calcium-binding proteins are abundant in the muscle of arthropods, mollusks, annelids, and protochordates.
This protein has three functional calcium-binding sites; potential site 2 has lost affinity for calcium.

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.