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Protein

Recombination and repair protein

Gene

UVSX

Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi60 – 67ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processDNA damage, DNA recombination, DNA repair, DNA replication
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Recombination and repair protein
Gene namesi
Name:UVSX
OrganismiEnterobacteria phage T4 (Bacteriophage T4)
Taxonomic identifieri10665 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000009087 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001229581 – 391Recombination and repair proteinAdd BLAST391

Structurei

Secondary structure

1391
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi37 – 44Combined sources8
Beta strandi53 – 65Combined sources13
Helixi66 – 80Combined sources15
Beta strandi85 – 92Combined sources8
Helixi97 – 102Combined sources6
Helixi107 – 109Combined sources3
Beta strandi110 – 114Combined sources5
Helixi118 – 130Combined sources13
Beta strandi138 – 143Combined sources6
Helixi168 – 185Combined sources18
Beta strandi189 – 195Combined sources7
Helixi214 – 217Combined sources4
Beta strandi218 – 226Combined sources9
Beta strandi239 – 246Combined sources8
Beta strandi248 – 250Combined sources3
Beta strandi255 – 260Combined sources6
Turni268 – 271Combined sources4
Helixi272 – 278Combined sources7
Beta strandi281 – 283Combined sources3
Beta strandi289 – 295Combined sources7
Turni297 – 299Combined sources3
Beta strandi302 – 304Combined sources3
Helixi311 – 314Combined sources4
Helixi317 – 324Combined sources8
Helixi327 – 337Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3IO5X-ray2.40A/B30-358[»]
ProteinModelPortaliP04529.
SMRiP04529.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP04529.

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.Curated

Phylogenomic databases

OrthoDBiVOG090000BH.

Family and domain databases

InterProiView protein in InterPro
IPR013765. DNA_recomb/repair_RecA.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR020587. RecA_monomer-monomer_interface.
PANTHERiPTHR22942:SF52. PTHR22942:SF52. 1 hit.
PfamiView protein in Pfam
PF00154. RecA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.

Sequencei

Sequence statusi: Complete.

P04529-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLKSRLIK ASTSKLTAEL TASKFFNEKD VVRTKIPMMN IALSGEITGG
60 70 80 90 100
MQSGLLILAG PSKSFKSNFG LTMVSSYMRQ YPDAVCLFYD SEFGITPAYL
110 120 130 140 150
RSMGVDPERV IHTPVQSLEQ LRIDMVNQLD AIERGEKVVV FIDSLGNLAS
160 170 180 190 200
KKETEDALNE KVVSDMTRAK TMKSLFRIVT PYFSTKNIPC IAINHTYETQ
210 220 230 240 250
EMFSKTVMGG GTGPMYSADT VFIIGKRQIK DGSDLQGYQF VLNVEKSRTV
260 270 280 290 300
KEKSKFFIDV KFDGGIDPYS GLLDMALELG FVVKPKNGWY AREFLDEETG
310 320 330 340 350
EMIREEKSWR AKDTNCTTFW GPLFKHQPFR DAIKRAYQLG AIDSNEIVEA
360 370 380 390
EVDELINSKV EKFKSPESKS KSAADLETDL EQLSDMEEFN E
Length:391
Mass (Da):43,998
Last modified:July 11, 2001 - v2
Checksum:i96A38E586706CB27
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti321 – 324GPLF → VLI in CAB40822 (PubMed:2932679).Curated4
Sequence conflicti321 – 324GPLF → VLI in AAA32552 (PubMed:2932679).Curated4

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03099 Genomic DNA. Translation: CAB40822.1.
AF158101 Genomic DNA. Translation: AAD42669.2.
J04978 Genomic DNA. Translation: AAA32523.1.
K03113 Genomic DNA. Translation: AAA32552.1.
PIRiA04307. RRBPT4.
RefSeqiNP_049656.2. NC_000866.4.

Genome annotation databases

GeneIDi1258704.
KEGGivg:1258704.

Similar proteinsi

Entry informationi

Entry nameiUVSX_BPT4
AccessioniPrimary (citable) accession number: P04529
Secondary accession number(s): Q9MBK8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: July 11, 2001
Last modified: September 27, 2017
This is version 97 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families