Reviewed,
UniProtKB/Swiss-Prot P04499 (TERM_ADE05)
Last modified
July 28, 2009.
Version 46.
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: DNA terminal protein Alternative name(s): Bellett protein pTP protein | ||
| Gene names |
| ||
| Organism | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) | ||
| Taxonomic identifier | 28285 [NCBI] | ||
| Taxonomic lineage | Viruses › dsDNA viruses, no RNA stage › Adenoviridae › Mastadenovirus | ||
| Virus host | Homo sapiens (Human) [TaxID: 9606] |
Protein attributes
| Sequence length | 653 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | This protein is covalently attached to the termini of replicating DNA in vivo and nascent DNA synthesized in vitro and may play some role in DNA replication. |
| Post-translational modification | The site of the covalent attachment of DNA is assigned by similarity to human adenovirus C serotype 2 DNA terminal protein. |
| Sequence similarities | Belongs to the adenoviridae terminal protein family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | DNA replication |
| PTM | Covalent protein-DNA linkage Phosphoprotein |
| Gene Ontology (GO) | |
| Biological process | DNA replication Inferred from electronic annotation. Source: UniProtKB-KW protein-DNA covalent cross-linkingInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | DNA binding Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The nucleotide sequence of fragment HindIII-C of human adenovirus type 5 DNA (map positions 17.1-31.7)." Dekker B.M.M., van Ormondt H. Gene 27:115-120(1984) [PubMed: 6325298] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2." Chroboczek J., Bieber F., Jacrot B. Virology 186:280-285(1992) [PubMed: 1727603] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [3] | "Structure of the linkage between adenovirus DNA and the 55,000 molecular weight terminal protein." Desiderio S.V., Kelly T.J. Jr. J. Mol. Biol. 145:319-337(1981) [PubMed: 7265205] [Abstract] Cited for: COVALENT DNA LINKAGE TO A SERINE. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | X02996 Genomic DNA. Translation: CAA26750.1. M73260 Genomic DNA. No translation available. |
| PIR | UZADP5. A03840. |
3D structure databases | |
| ModBase | Search... |
Family and domain databases | |
| InterPro | IPR003391. Adeno_terminal. [Graphical view] |
| Pfam | PF02459. Adeno_terminal. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TERM_ADE05 | ||||||||
| Accession | Primary (citable) accession number: P04499 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Virus (Virus annotation project) | ||||||||
