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Protein

Probable early E4 11 kDa protein

Gene
N/A
Organism
Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • identical protein binding Source: IntAct
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Probable early E4 11 kDa protein
OrganismiHuman adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Taxonomic identifieri28285 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageAdenoviridaeMastadenovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000004992 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 116116Probable early E4 11 kDa proteinPRO_0000221771Add
BLAST

Expressioni

Keywords - Developmental stagei

Early protein

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself5EBI-6398911,EBI-6398911
PMLP29590-34EBI-6398911,EBI-8099068From a different organism.

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

DIPiDIP-571N.
IntActiP04489. 3 interactions.
MINTiMINT-146166.

Structurei

Secondary structure

1
116
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi2 – 109Combined sources
Helixi11 – 199Combined sources
Helixi24 – 3714Combined sources
Helixi38 – 425Combined sources
Beta strandi47 – 537Combined sources
Beta strandi55 – 6612Combined sources
Helixi70 – 9627Combined sources
Beta strandi108 – 1114Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DJBX-ray2.05A/B1-116[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR009699. Adenovirus-2_E4/Orf3.
[Graphical view]
PfamiPF06931. Adeno_E4_ORF3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P04489-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRCLRLKVE GALEQIFTMA GLNIRDLLRD ILRRWRDENY LGMVEGAGMF
60 70 80 90 100
IEEIHPEGFS LYVHLDVRAV CLLEAIVQHL TNAIICSLAV EFDHATGGER
110
VHLIDLHFEV LDNLLE
Length:116
Mass (Da):13,298
Last modified:August 13, 1987 - v1
Checksum:iAE4EF38B8F81EE0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M73260 Genomic DNA. No translation available.
X02998 Genomic DNA. Translation: CAA26757.1.
PIRiB03807. Q4ADE5.
RefSeqiAP_000230.1. AC_000008.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M73260 Genomic DNA. No translation available.
X02998 Genomic DNA. Translation: CAA26757.1.
PIRiB03807. Q4ADE5.
RefSeqiAP_000230.1. AC_000008.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DJBX-ray2.05A/B1-116[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-571N.
IntActiP04489. 3 interactions.
MINTiMINT-146166.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

PROiP04489.

Family and domain databases

InterProiIPR009699. Adenovirus-2_E4/Orf3.
[Graphical view]
PfamiPF06931. Adeno_E4_ORF3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix."
    Sarnow P., Hearing P., Anderson C.W., Reich N., Levine A.J.
    J. Mol. Biol. 162:565-583(1982) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2."
    Chroboczek J., Bieber F., Jacrot B.
    Virology 186:280-285(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiE411_ADE05
AccessioniPrimary (citable) accession number: P04489
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 13, 1987
Last modified: May 11, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.