Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Colicin-E2 immunity protein

Gene

imm

Organism
Escherichia coli
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

This protein is able to protect a cell, which harbors the plasmid ColE2 encoding colicin E2, against colicin E2.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacteriocin immunity

Names & Taxonomyi

Protein namesi
Recommended name:
Colicin-E2 immunity protein
Alternative name(s):
ImmE2
Microcin-E2 immunity protein
Gene namesi
Name:imm
Synonyms:ceiB
Encoded oniPlasmid ColE2-P90 Publication
OrganismiEscherichia coli
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8686Colicin-E2 immunity proteinPRO_0000218703Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-59336N.

Structurei

Secondary structure

1
86
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 93Combined sources
Helixi12 – 2413Combined sources
Beta strandi27 – 293Combined sources
Helixi30 – 4415Combined sources
Turni47 – 504Combined sources
Helixi51 – 544Combined sources
Beta strandi58 – 603Combined sources
Helixi64 – 7714Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2NO8NMR-A1-86[»]
2WPTX-ray1.78A1-86[»]
3U43X-ray1.72A1-86[»]
ProteinModelPortaliP04482.
SMRiP04482. Positions 2-86.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP04482.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.1200.20. 1 hit.
InterProiIPR023802. Colicin/pyocin_immunity_dom.
IPR000290. Colicin_pyocin.
[Graphical view]
PfamiPF01320. Colicin_Pyocin. 1 hit.
[Graphical view]
PRINTSiPR01299. PYOCIN.
ProDomiPD007225. Colicin_pyocin. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47345. SSF47345. 1 hit.

Sequencei

Sequence statusi: Complete.

P04482-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELKHSISDY TEAEFLEFVK KICRAEGATE EDDNKLVREF ERLTEHPDGS
60 70 80
DLIYYPRDDR EDSPEGIVKE IKEWRAANGK SGFKQG
Length:86
Mass (Da):9,995
Last modified:August 13, 1987 - v1
Checksum:i1C5C89ED7E87BC39
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02227 Genomic DNA. Translation: CAA26146.1.
X01163 Genomic DNA. Translation: CAA25610.1.
M29885 Genomic DNA. Translation: AAA23069.1.
PIRiA03512. IMECE2.
RefSeqiWP_000420693.1. NZ_LMBJ01000169.1.
YP_001966153.1. NC_010883.1.
YP_002221665.1. NC_011228.1.

Genome annotation databases

GeneIDi6383670.
6921858.
KEGGipg:6383670.
pg:6921858.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02227 Genomic DNA. Translation: CAA26146.1.
X01163 Genomic DNA. Translation: CAA25610.1.
M29885 Genomic DNA. Translation: AAA23069.1.
PIRiA03512. IMECE2.
RefSeqiWP_000420693.1. NZ_LMBJ01000169.1.
YP_001966153.1. NC_010883.1.
YP_002221665.1. NC_011228.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2NO8NMR-A1-86[»]
2WPTX-ray1.78A1-86[»]
3U43X-ray1.72A1-86[»]
ProteinModelPortaliP04482.
SMRiP04482. Positions 2-86.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-59336N.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6383670.
6921858.
KEGGipg:6383670.
pg:6921858.

Miscellaneous databases

EvolutionaryTraceiP04482.

Family and domain databases

Gene3Di1.10.1200.20. 1 hit.
InterProiIPR023802. Colicin/pyocin_immunity_dom.
IPR000290. Colicin_pyocin.
[Graphical view]
PfamiPF01320. Colicin_Pyocin. 1 hit.
[Graphical view]
PRINTSiPR01299. PYOCIN.
ProDomiPD007225. Colicin_pyocin. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47345. SSF47345. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparative nucleotide sequences encoding the immunity proteins and the carboxyl-terminal peptides of colicins E2 and E3."
    Lau P.C.K., Rowsome R.W., Zuker M., Visentin L.P.
    Nucleic Acids Res. 12:8733-8745(1984) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Structure and expression of the ColE2-P9 immunity gene."
    Masaki H., Toba M., Ohta T.
    Nucleic Acids Res. 13:1623-1635(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Molecular characterisation of the colicin E2 operon and identification of its products."
    Cole S.T., Saint-Joanis B., Pugsley A.P.
    Mol. Gen. Genet. 198:465-472(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiIMM2_ECOLX
AccessioniPrimary (citable) accession number: P04482
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 13, 1987
Last modified: May 11, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Plasmid

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.