ID   CALM_WHEAT              Reviewed;         149 AA.
AC   P04464;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   22-SEP-2009, entry version 61.
DE   RecName: Full=Calmodulin;
DE            Short=CaM;
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Pooideae; Triticeae; Triticum.
OX   NCBI_TaxID=4565;
RN   [1]
RP   PROTEIN SEQUENCE OF 2-149.
RC   TISSUE=Germ;
RX   MEDLINE=86111690; PubMed=4086472;
RA   Toda H., Yazawa M., Sakiyama F., Yagi K.;
RT   "Amino acid sequence of calmodulin from wheat germ.";
RL   J. Biochem. 98:833-842(1985).
RN   [2]
RP   ERRATUM, AND SEQUENCE REVISION.
RX   MEDLINE=94266769; PubMed=8206888;
RA   Toda H., Yazawa M., Sakiyama F., Yagi K.;
RL   J. Biochem. 115:367-367(1994).
CC   -!- FUNCTION: Calmodulin mediates the control of a large number of
CC       enzymes and other proteins by Ca(2+). Among the enzymes to be
CC       stimulated by the calmodulin-Ca(2+) complex are a number of
CC       protein kinases and phosphatases.
CC   -!- MISCELLANEOUS: This protein has four functional calcium-binding
CC       sites.
CC   -!- SIMILARITY: Belongs to the calmodulin family.
CC   -!- SIMILARITY: Contains 4 EF-hand domains.
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DR   PIR; A03025; MCWT.
DR   HSSP; P02593; 1F70.
DR   SMR; P04464; 1-148.
DR   Gramene; P04464; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR011992; EF-Hand_type.
DR   InterPro; IPR018248; EF_hand.
DR   InterPro; IPR018247; EF_HAND_1_Ca_BS.
DR   InterPro; IPR018249; EF_HAND_2.
DR   InterPro; IPR002048; EF_hand_Ca_bd.
DR   Gene3D; G3DSA:1.10.238.10; EF-Hand_type; 1.
DR   Pfam; PF00036; efhand; 4.
DR   ProDom; PD000012; EF-hand; 2.
DR   SMART; SM00054; EFh; 4.
DR   PROSITE; PS00018; EF_HAND_1; 4.
DR   PROSITE; PS50222; EF_HAND_2; 4.
PE   1: Evidence at protein level;
KW   Acetylation; Calcium; Direct protein sequencing; Methylation; Repeat.
FT   INIT_MET      1      1       Removed.
FT   CHAIN         2    149       Calmodulin.
FT                                /FTId=PRO_0000198308.
FT   DOMAIN        8     43       EF-hand 1.
FT   DOMAIN       44     79       EF-hand 2.
FT   DOMAIN       81    116       EF-hand 3.
FT   DOMAIN      117    149       EF-hand 4.
FT   CA_BIND      21     32       1.
FT   CA_BIND      57     68       2.
FT   CA_BIND      94    105       3.
FT   CA_BIND     130    141       4.
FT   MOD_RES       2      2       N-acetylalanine.
FT   MOD_RES     116    116       N6,N6,N6-trimethyllysine.
SQ   SEQUENCE   149 AA;  16847 MW;  9E5AF05D066A759C CRC64;
     MADQLTDEQI AEFKEAFSLF DKDGDGCITT KELGTVMRSL GQNPTEAELQ DMINEVDADG
     NGTIDFPEFL NLMARKMKDT DSEEELKEAF RVFDKDQDGF ISAAELRHVM TNLGEKLTDE
     EVDEMIREAD VDGDGQINYE EFVKVMMAK
//