P04464 (CALM_WHEAT) Reviewed, UniProtKB/Swiss-Prot
Last modified
September 21, 2011.
Version 69.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Calmodulin Short name=CaM |
| Organism | Triticum aestivum (Wheat) |
| Taxonomic identifier | 4565 [NCBI] |
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Triticum |
Protein attributes
| Sequence length | 149 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. |
| Miscellaneous | This protein has four functional calcium-binding sites. |
| Sequence similarities | Belongs to the calmodulin family. Contains 4 EF-hand domains. |
Ontologies
| Keywords | |
|---|---|
| Domain | Repeat |
| Ligand | Calcium |
| PTM | Acetylation Methylation |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Molecular function | calcium ion binding Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Initiator methionine | 1 | 1 | Removed Ref.1 | ||||||
| Chain | 2 – 149 | 148 | Calmodulin | PRO_0000198308 | |||||
Regions | |||||||||
| Domain | 8 – 43 | 36 | EF-hand 1 | ||||||
| Domain | 44 – 79 | 36 | EF-hand 2 | ||||||
| Domain | 81 – 116 | 36 | EF-hand 3 | ||||||
| Domain | 117 – 149 | 33 | EF-hand 4 | ||||||
| Calcium binding | 21 – 32 | 12 | 1 | ||||||
| Calcium binding | 57 – 68 | 12 | 2 | ||||||
| Calcium binding | 94 – 105 | 12 | 3 | ||||||
| Calcium binding | 130 – 141 | 12 | 4 | ||||||
Amino acid modifications | |||||||||
| Modified residue | 2 | 1 | N-acetylalanine Ref.1 | ||||||
| Modified residue | 116 | 1 | N6,N6,N6-trimethyllysine Ref.1 | ||||||
Sequences
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References
| [1] | "Amino acid sequence of calmodulin from wheat germ." Toda H., Yazawa M., Sakiyama F., Yagi K. J. Biochem. 98:833-842(1985) [PubMed: 4086472] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-149. Tissue: Germ. |
| [2] | Erratum Toda H., Yazawa M., Sakiyama F., Yagi K. J. Biochem. 115:367-367(1994) [PubMed: 8206888] [Abstract] Cited for: SEQUENCE REVISION. |
Cross-references
Sequence databases | |
|---|---|
| PIR | MCWT. A03025. |
3D structure databases | |
| ProteinModelPortal | P04464. |
| SMR | P04464. Positions 1-148. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Organism-specific databases | |
| Gramene | P04464. |
Family and domain databases | |
| InterPro | IPR018248. EF-hand. IPR011992. EF-hand-like_dom. IPR018247. EF_Hand_1_Ca_BS. IPR018249. EF_HAND_2. IPR002048. EF_hand_Ca-bd. [Graphical view] |
| Gene3D | G3DSA:1.10.238.10. EF-Hand_type. 2 hits. |
| Pfam | PF00036. efhand. 4 hits. [Graphical view] |
| SMART | SM00054. EFh. 4 hits. [Graphical view] |
| PROSITE | PS00018. EF_HAND_1. 4 hits. PS50222. EF_HAND_2. 4 hits. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | CALM_WHEAT | ||||||||
| Accession | Primary (citable) accession number: P04464 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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