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Reviewed, UniProtKB/Swiss-Prot P04464 (CALM_WHEAT)

Last modified June 16, 2009. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Calmodulin
      Short name=CaM
OrganismTriticum aestivum (Wheat)
Taxonomic identifier4565 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeTriticum

Protein attributes

Sequence length149 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Calmodulin mediates the control of a large number of enzymes and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases.

Miscellaneous

This protein has four functional calcium-binding sites.

Sequence similarities

Belongs to the calmodulin family.

Contains 4 EF-hand domains.

Ontologies

Keywords
   DomainRepeat
   LigandCalcium
   PTMAcetylation
Methylation
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Molecular functioncalcium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.1
Chain2 – 149148Calmodulin
PRO_0000198308

Regions

Domain8 – 4336EF-hand 1
Domain44 – 7936EF-hand 2
Domain81 – 11636EF-hand 3
Domain117 – 14933EF-hand 4
Calcium binding21 – 32121
Calcium binding57 – 68122
Calcium binding94 – 105123
Calcium binding130 – 141124

Amino acid modifications

Modified residue21N-acetylalanine Ref.1
Modified residue1161N6,N6,N6-trimethyllysine Ref.1

Sequences

Sequence LengthMass (Da)Tools
P04464-1 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 9E5AF05D066A759C

FASTA14916,847
        10         20         30         40         50         60 
MADQLTDEQI AEFKEAFSLF DKDGDGCITT KELGTVMRSL GQNPTEAELQ DMINEVDADG 

        70         80         90        100        110        120 
NGTIDFPEFL NLMARKMKDT DSEEELKEAF RVFDKDQDGF ISAAELRHVM TNLGEKLTDE 

       130        140 
EVDEMIREAD VDGDGQINYE EFVKVMMAK 

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References

[1]"Amino acid sequence of calmodulin from wheat germ."
Toda H., Yazawa M., Sakiyama F., Yagi K.
J. Biochem. 98:833-842(1985) [PubMed: 4086472] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-149.
Tissue: Germ.
[2]Erratum
Toda H., Yazawa M., Sakiyama F., Yagi K.
J. Biochem. 115:367-367(1994) [PubMed: 8206888] [Abstract]
Cited for: SEQUENCE REVISION.

Cross-references

Sequence databases

PIRMCWT. A03025.

3D structure databases

HSSPHSSP built from PDB template 1F70 based on UniProtKB P02593.
SMRP04464. Positions 1-148.
ModBaseSearch...

Organism-specific databases

GrameneP04464.

Family and domain databases

InterProIPR011992. EF-Hand_type.
IPR018248. EF_hand.
IPR018247. EF_HAND_1.
IPR018249. EF_HAND_2.
IPR002048. EF_hand_Ca_bd.
[Graphical view]
Gene3DG3DSA:1.10.238.10. EF-Hand_type. 1 hit.
PfamPF00036. efhand. 4 hits.
[Graphical view]
ProDomPD000012. EF-hand. 2 hits.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00054. EFh. 4 hits.
[Graphical view]
PROSITEPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCALM_WHEAT
AccessionPrimary (citable) accession number: P04464
Entry history
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: January 23, 2007
Last modified: June 16, 2009
This is version 60 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents