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P04450

- RL14_GEOSE

UniProt

P04450 - RL14_GEOSE

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Protein
50S ribosomal protein L14
Gene
rplN
Organism
Geobacillus stearothermophilus (Bacillus stearothermophilus)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Forms part of two intersubunit bridges in the 70S ribosome By similarity. Binds to 23S rRNA.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L14
Gene namesi
Name:rplN
OrganismiGeobacillus stearothermophilus (Bacillus stearothermophilus)
Taxonomic identifieri1422 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Subcellular locationi

GO - Cellular componenti

  1. large ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12212250S ribosomal protein L14UniRule annotation
PRO_0000128529Add
BLAST

Proteomic databases

PRIDEiP04450.

Interactioni

Subunit structurei

Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8 By similarity. Part of the 50S ribosomal subunit.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi7 – 104
Beta strandi12 – 2413
Beta strandi38 – 469
Beta strandi50 – 523
Beta strandi57 – 648
Beta strandi83 – 875
Beta strandi93 – 964
Helixi105 – 1084
Helixi112 – 1176

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WHIX-ray1.50A1-122[»]
2B9PX-ray6.46O1-122[»]
ProteinModelPortaliP04450.
SMRiP04450. Positions 1-122.

Miscellaneous databases

EvolutionaryTraceiP04450.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di2.40.150.20. 1 hit.
HAMAPiMF_01367. Ribosomal_L14.
InterProiIPR005745. Ribosomal_L14_bac-type.
IPR019972. Ribosomal_L14_CS.
IPR023571. Ribosomal_L14_dom.
IPR000218. Ribosomal_L14b/L23e.
[Graphical view]
PANTHERiPTHR11761. PTHR11761. 1 hit.
PfamiPF00238. Ribosomal_L14. 1 hit.
[Graphical view]
SUPFAMiSSF50193. SSF50193. 1 hit.
TIGRFAMsiTIGR01067. rplN_bact. 1 hit.
PROSITEiPS00049. RIBOSOMAL_L14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P04450-1 [UniParc]FASTAAdd to Basket

« Hide

MIQQESRLKV ADNSGAREVL VIKVLGGSGR RYANIGDVVV ATVKDATPGG    50
VVKKGQVVKA VVVRTKRGVR RPDGSYIRFD ENACVIIRDD KSPRGTRIFG 100
PVARELRDKD FMKIISLAPE VI 122
Length:122
Mass (Da):13,346
Last modified:August 13, 1987 - v1
Checksum:iEF0BA6CD5927D324
GO

Sequence databases

PIRiA02789. R5BS14.

Cross-referencesi

Sequence databases

PIRi A02789. R5BS14.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1WHI X-ray 1.50 A 1-122 [» ]
2B9P X-ray 6.46 O 1-122 [» ]
ProteinModelPortali P04450.
SMRi P04450. Positions 1-122.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P04450.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P04450.

Family and domain databases

Gene3Di 2.40.150.20. 1 hit.
HAMAPi MF_01367. Ribosomal_L14.
InterProi IPR005745. Ribosomal_L14_bac-type.
IPR019972. Ribosomal_L14_CS.
IPR023571. Ribosomal_L14_dom.
IPR000218. Ribosomal_L14b/L23e.
[Graphical view ]
PANTHERi PTHR11761. PTHR11761. 1 hit.
Pfami PF00238. Ribosomal_L14. 1 hit.
[Graphical view ]
SUPFAMi SSF50193. SSF50193. 1 hit.
TIGRFAMsi TIGR01067. rplN_bact. 1 hit.
PROSITEi PS00049. RIBOSOMAL_L14. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete primary structure of ribosomal proteins L1, L14, L15, L23, L24 and L29 from Bacillus stearothermophilus."
    Kimura M., Kimura J., Ashman K.
    Eur. J. Biochem. 150:491-497(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
  2. "Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross-linking studies."
    Urlaub H., Kruft V., Bischof O., Mueller E.-C., Wittmann-Liebold B.
    EMBO J. 14:4578-4588(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 24-35, CROSS-LINKING TO RRNA.
    Strain: 799.
  3. "The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus."
    Davies C., White S.W., Ramakrishnan V.
    Structure 4:55-66(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS).
  4. "Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit."
    Ban N., Nissen P., Hansen J., Capel M., Moore P.B., Steitz T.A.
    Nature 400:841-847(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: 3D-STRUCTURE MODELING ONTO THE H.MARISMORTUI 50S RIBOSOME.

Entry informationi

Entry nameiRL14_GEOSE
AccessioniPrimary (citable) accession number: P04450
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 13, 1987
Last modified: March 19, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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