Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P04450 (RL14_GEOSE) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L14
Gene names
Name:rplN
OrganismGeobacillus stearothermophilus (Bacillus stearothermophilus)
Taxonomic identifier1422 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length122 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Forms part of two intersubunit bridges in the 70S ribosome By similarity. Binds to 23S rRNA. HAMAP-Rule MF_01367

Subunit structure

Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8 By similarity. Part of the 50S ribosomal subunit.

Sequence similarities

Belongs to the ribosomal protein L14P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical term3D-structure
Direct protein sequencing
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentlarge ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12212250S ribosomal protein L14 HAMAP-Rule MF_01367
PRO_0000128529

Secondary structure

................... 122
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P04450 [UniParc].

Last modified August 13, 1987. Version 1.
Checksum: EF0BA6CD5927D324

FASTA12213,346
        10         20         30         40         50         60 
MIQQESRLKV ADNSGAREVL VIKVLGGSGR RYANIGDVVV ATVKDATPGG VVKKGQVVKA 

        70         80         90        100        110        120 
VVVRTKRGVR RPDGSYIRFD ENACVIIRDD KSPRGTRIFG PVARELRDKD FMKIISLAPE 


VI 

« Hide

References

[1]"The complete primary structure of ribosomal proteins L1, L14, L15, L23, L24 and L29 from Bacillus stearothermophilus."
Kimura M., Kimura J., Ashman K.
Eur. J. Biochem. 150:491-497(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
[2]"Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross-linking studies."
Urlaub H., Kruft V., Bischof O., Mueller E.-C., Wittmann-Liebold B.
EMBO J. 14:4578-4588(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 24-35, CROSS-LINKING TO RRNA.
Strain: 799.
[3]"The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus."
Davies C., White S.W., Ramakrishnan V.
Structure 4:55-66(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS).
[4]"Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit."
Ban N., Nissen P., Hansen J., Capel M., Moore P.B., Steitz T.A.
Nature 400:841-847(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: 3D-STRUCTURE MODELING ONTO THE H.MARISMORTUI 50S RIBOSOME.
+Additional computationally mapped references.

Cross-references

Sequence databases

PIRR5BS14. A02789.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1WHIX-ray1.50A1-122[»]
2B9PX-ray6.46O1-122[»]
ProteinModelPortalP04450.
SMRP04450. Positions 1-122.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP04450.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.40.150.20. 1 hit.
HAMAPMF_01367. Ribosomal_L14.
InterProIPR005745. Ribosomal_L14_bac-type.
IPR019972. Ribosomal_L14_CS.
IPR023571. Ribosomal_L14_dom.
IPR000218. Ribosomal_L14b/L23e.
[Graphical view]
PANTHERPTHR11761. PTHR11761. 1 hit.
PfamPF00238. Ribosomal_L14. 1 hit.
[Graphical view]
SUPFAMSSF50193. SSF50193. 1 hit.
TIGRFAMsTIGR01067. rplN_bact. 1 hit.
PROSITEPS00049. RIBOSOMAL_L14. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP04450.

Entry information

Entry nameRL14_GEOSE
AccessionPrimary (citable) accession number: P04450
Entry history
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 13, 1987
Last modified: March 19, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references