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Protein

Glycinin G2

Gene

Gy2

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Glycinin is the major seed storage protein of soybean.

GO - Molecular functioni

Keywordsi

Molecular functionSeed storage protein, Storage protein

Names & Taxonomyi

Protein namesi
Recommended name:
Glycinin G2
Cleaved into the following 2 chains:
Gene namesi
Name:Gy2
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
Proteomesi
  • UP000008827 Componenti: Chromosome 3

Pathology & Biotechi

Protein family/group databases

Allergomei1143 Gly m 6.0201
5821 Gly m 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 181 PublicationAdd BLAST18
ChainiPRO_000003201319 – 296Glycinin A2 subunitAdd BLAST278
PropeptideiPRO_0000032014297 – 3001 Publication4
ChainiPRO_0000032015301 – 480Glycinin B1a subunitAdd BLAST180
PropeptideiPRO_0000032016481 – 4855

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi28 ↔ 61By similarity
Disulfide bondi104 ↔ 307Interchain (between A2 and B1a chains)1 Publication

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP04405

Interactioni

Subunit structurei

Hexamer; each subunit is composed of an acidic and a basic chain derived from a single precursor and linked by a disulfide bond.

Structurei

3D structure databases

ProteinModelPortaliP04405
SMRiP04405
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiP04405

Family and domain databases

Gene3Di2.60.120.10, 2 hits
InterProiView protein in InterPro
IPR022379 11S_seedstore_CS
IPR006044 11S_seedstore_pln
IPR006045 Cupin_1
IPR014710 RmlC-like_jellyroll
IPR011051 RmlC_Cupin_sf
PfamiView protein in Pfam
PF00190 Cupin_1, 2 hits
PRINTSiPR00439 11SGLOBULIN
SMARTiView protein in SMART
SM00835 Cupin_1, 2 hits
SUPFAMiSSF51182 SSF51182, 3 hits
PROSITEiView protein in PROSITE
PS00305 11S_SEED_STORAGE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P04405-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLVLSLCF LLFSGCFALR EQAQQNECQI QKLNALKPDN RIESEGGFIE
60 70 80 90 100
TWNPNNKPFQ CAGVALSRCT LNRNALRRPS YTNGPQEIYI QQGNGIFGMI
110 120 130 140 150
FPGCPSTYQE PQESQQRGRS QRPQDRHQKV HRFREGDLIA VPTGVAWWMY
160 170 180 190 200
NNEDTPVVAV SIIDTNSLEN QLDQMPRRFY LAGNQEQEFL KYQQQQQGGS
210 220 230 240 250
QSQKGKQQEE ENEGSNILSG FAPEFLKEAF GVNMQIVRNL QGENEEEDSG
260 270 280 290 300
AIVTVKGGLR VTAPAMRKPQ QEEDDDDEEE QPQCVETDKG CQRQSKRSRN
310 320 330 340 350
GIDETICTMR LRQNIGQNSS PDIYNPQAGS ITTATSLDFP ALWLLKLSAQ
360 370 380 390 400
YGSLRKNAMF VPHYTLNANS IIYALNGRAL VQVVNCNGER VFDGELQEGG
410 420 430 440 450
VLIVPQNFAV AAKSQSDNFE YVSFKTNDRP SIGNLAGANS LLNALPEEVI
460 470 480
QHTFNLKSQQ ARQVKNNNPF SFLVPPQESQ RRAVA
Length:485
Mass (Da):54,391
Last modified:October 1, 1989 - v2
Checksum:i78BB459837F77AD8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti39D → G in CAA26575 (Ref. 5) Curated1
Sequence conflicti39D → N AA sequence (PubMed:6541652).Curated1
Sequence conflicti61C → S AA sequence (PubMed:6541652).Curated1
Sequence conflicti117R → C AA sequence (PubMed:6541652).Curated1
Sequence conflicti343W → S AA sequence (PubMed:6541652).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti103G → D. 1
Natural varianti318N → T. 1
Natural varianti331I → V. 1
Natural varianti413K → R. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15122 Genomic DNA Translation: CAA33216.1
D00216 mRNA Translation: BAA00154.1
Y00398 Genomic DNA Translation: CAA68460.1
X02806 mRNA Translation: CAA26575.1
K02646 Genomic DNA Translation: AAA33963.1
X53404 Genomic DNA Translation: CAA37480.1
PIRiA91341 FWSYG1
S11002
RefSeqiNP_001235810.1, NM_001248881.1
UniGeneiGma.1857

Genome annotation databases

EnsemblPlantsiKRH67383; KRH67383; GLYMA_03G163500
GeneIDi547900
GrameneiKRH67383; KRH67383; GLYMA_03G163500
KEGGigmx:547900

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiGLYG2_SOYBN
AccessioniPrimary (citable) accession number: P04405
Secondary accession number(s): P04121, P04348, P04349
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 1987
Last sequence update: October 1, 1989
Last modified: April 25, 2018
This is version 111 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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