Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P04383 (CAPSD_CARMV) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Capsid protein
Alternative name(s):
Coat protein
p38
Gene names
ORF Names:ORF4
OrganismCarnation mottle virus (CarMV)
Taxonomic identifier11986 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeCarmovirus
Virus hostBegonia [TaxID: 3681]
Dianthus barbatus [TaxID: 278075]
Dianthus caryophyllus (Carnation) (Clove pink) [TaxID: 3570]
Dianthus chinensis [TaxID: 118431]
Dianthus superbus [TaxID: 288950]
Malus domestica (Apple) (Pyrus malus) [TaxID: 3750]
Saponaria officinalis (Common soapwort) (Lychnis saponaria) [TaxID: 3572]

Protein attributes

Sequence length348 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs By similarity.

Cofactor

Binds calcium ions. Calcium ions probably promote virus assembly and stabilize the virus particle By similarity.

Subunit structure

Homodimer By similarity. Homomultimer By similarity.

Subcellular location

Virion By similarity.

Sequence similarities

Belongs to the icosahedral plant coat protein family.

Ontologies

Keywords
   Cellular componentCapsid protein
T=3 icosahedral capsid protein
Virion
   LigandCalcium
RNA-binding
   Technical term3D-structure
Gene Ontology (GO)
   Cellular_componentT=3 icosahedral viral capsid

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

structural molecule activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 348348Capsid protein
PRO_0000222860

Regions

Region1 – 8181R domain, disordered, interaction with RNA
Region82 – 239158S domain, virion shell
Region240 – 348109P domain, projecting

Secondary structure

................................................... 348
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P04383 [UniParc].

Last modified March 20, 1987. Version 1.
Checksum: E9EEA336C45B0D39

FASTA34837,787
        10         20         30         40         50         60 
MENKGEKIAM NPTVQTLAQK GDKLAVKLVT RGWASLSTNQ KRRAEMLAGY TPAILAFTPR 

        70         80         90        100        110        120 
RPRMTNPPPR TSRNSPGQAG KSMTMSKTEL LSTVKGTTGV IPSFEDWVVS PRNVAVFPQL 

       130        140        150        160        170        180 
SLLATNFNKY RITALTVKYS PACSFETNGR VALGFNDDAS DTPPTTKVGF YDLGKHVETA 

       190        200        210        220        230        240 
AQTAKDLVIP VDGKTRFIRD SASDDAKLVD FGRIVLSTYG FDKADTVVGE LFIQYTIVLS 

       250        260        270        280        290        300 
DPTKTAKISQ ASNDKVSDGP TYVVPSVNGN ELQLRVVAAG KWCIIVRGTV EGGFTKPTLI 

       310        320        330        340 
GPGISGDVDY ESARPIAVCE LVTQMEGQIL KITKTSAEQP LQWVVYRM 

« Hide

References

[1]"Nucleotide sequence and genome organization of carnation mottle virus RNA."
Guilley H., Carrington J.C., Balazs E., Jonard G., Richards K., Morris T.J.
Nucleic Acids Res. 13:6663-6677(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"The atomic structure of Carnation mottle virus capsid protein."
Morgunova E.Y., Dauter Z., Stuart D.I., Stel'Mashchuk V.Y., Mikhailov A.M., Wilson K.S., Vainshtein B.K.
FEBS Lett. 338:267-271(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS).

Web resources

Virus Particle ExploreR db

Icosahedral capsid structure

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X02986 Genomic RNA. Translation: CAA26728.1.
PIRVCVECV. A04209.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1OPOX-ray3.20A/B/C1-348[»]
ProteinModelPortalP04383.
SMRP04383. Positions 81-348.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.120.20. 1 hit.
InterProIPR000937. Capsid_prot_S-dom_vir.
IPR013669. Coat_prot_C_Carmovir.
IPR029053. Viral_coat.
[Graphical view]
PfamPF08462. Carmo_coat_C. 1 hit.
PF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSPR00233. ICOSAHEDRAL.
PROSITEPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP04383.

Entry information

Entry nameCAPSD_CARMV
AccessionPrimary (citable) accession number: P04383
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 1987
Last sequence update: March 20, 1987
Last modified: July 9, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references