Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P04383

- CAPSD_CARMV

UniProt

P04383 - CAPSD_CARMV

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Capsid protein

Gene

ORF4

Organism
Carnation mottle virus (CarMV)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs By similarity.By similarity

Cofactori

Binds calcium ions. Calcium ions probably promote virus assembly and stabilize the virus particle By similarity.By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
  2. structural molecule activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Calcium, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid protein
Alternative name(s):
Coat protein
p38
Gene namesi
ORF Names:ORF4
OrganismiCarnation mottle virus (CarMV)
Taxonomic identifieri11986 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeCarmovirus
Virus hostiBegonia [TaxID: 3681]
Dianthus barbatus [TaxID: 278075]
Dianthus caryophyllus (Carnation) (Clove pink) [TaxID: 3570]
Dianthus chinensis [TaxID: 118431]
Dianthus superbus [TaxID: 288950]
Malus domestica (Apple) (Pyrus malus) [TaxID: 3750]
Saponaria officinalis (Common soapwort) (Lychnis saponaria) [TaxID: 3572]

Subcellular locationi

Virion By similarity

GO - Cellular componenti

  1. T=3 icosahedral viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, T=3 icosahedral capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 348348Capsid proteinPRO_0000222860Add
BLAST

Interactioni

Subunit structurei

Homodimer. Homomultimer.By similarity

Structurei

Secondary structure

1
348
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi84 – 9512
Beta strandi98 – 1014
Beta strandi103 – 1097
Turni114 – 1163
Helixi118 – 1247
Beta strandi127 – 14115
Beta strandi150 – 1578
Helixi167 – 1715
Beta strandi173 – 1808
Beta strandi185 – 1895
Helixi206 – 2094
Beta strandi212 – 2198
Beta strandi221 – 2255
Beta strandi227 – 24216
Beta strandi249 – 2513
Helixi255 – 2573
Beta strandi263 – 2686
Beta strandi271 – 2766
Beta strandi278 – 28710
Beta strandi289 – 2946
Beta strandi298 – 3014
Beta strandi304 – 3118
Turni312 – 3154
Beta strandi316 – 32510
Beta strandi328 – 3347
Beta strandi342 – 3476

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1OPOX-ray3.20A/B/C1-348[»]
ProteinModelPortaliP04383.
SMRiP04383. Positions 81-348.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP04383.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 8181R domain, disordered, interaction with RNAAdd
BLAST
Regioni82 – 239158S domain, virion shellAdd
BLAST
Regioni240 – 348109P domain, projectingAdd
BLAST

Sequence similaritiesi

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR013669. Coat_prot_C_Carmovir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF08462. Carmo_coat_C. 1 hit.
PF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P04383-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MENKGEKIAM NPTVQTLAQK GDKLAVKLVT RGWASLSTNQ KRRAEMLAGY
60 70 80 90 100
TPAILAFTPR RPRMTNPPPR TSRNSPGQAG KSMTMSKTEL LSTVKGTTGV
110 120 130 140 150
IPSFEDWVVS PRNVAVFPQL SLLATNFNKY RITALTVKYS PACSFETNGR
160 170 180 190 200
VALGFNDDAS DTPPTTKVGF YDLGKHVETA AQTAKDLVIP VDGKTRFIRD
210 220 230 240 250
SASDDAKLVD FGRIVLSTYG FDKADTVVGE LFIQYTIVLS DPTKTAKISQ
260 270 280 290 300
ASNDKVSDGP TYVVPSVNGN ELQLRVVAAG KWCIIVRGTV EGGFTKPTLI
310 320 330 340
GPGISGDVDY ESARPIAVCE LVTQMEGQIL KITKTSAEQP LQWVVYRM
Length:348
Mass (Da):37,787
Last modified:March 20, 1987 - v1
Checksum:iE9EEA336C45B0D39
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X02986 Genomic RNA. Translation: CAA26728.1.
PIRiA04209. VCVECV.
RefSeqiYP_009032648.1. NC_001265.2.

Genome annotation databases

GeneIDi19493256.

Cross-referencesi

Web resourcesi

Virus Particle ExploreR db

Icosahedral capsid structure

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X02986 Genomic RNA. Translation: CAA26728.1 .
PIRi A04209. VCVECV.
RefSeqi YP_009032648.1. NC_001265.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1OPO X-ray 3.20 A/B/C 1-348 [» ]
ProteinModelPortali P04383.
SMRi P04383. Positions 81-348.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 19493256.

Miscellaneous databases

EvolutionaryTracei P04383.

Family and domain databases

Gene3Di 2.60.120.20. 1 hit.
InterProi IPR000937. Capsid_prot_S-dom_vir.
IPR013669. Coat_prot_C_Carmovir.
IPR029053. Viral_coat.
[Graphical view ]
Pfami PF08462. Carmo_coat_C. 1 hit.
PF00729. Viral_coat. 1 hit.
[Graphical view ]
PRINTSi PR00233. ICOSAHEDRAL.
PROSITEi PS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence and genome organization of carnation mottle virus RNA."
    Guilley H., Carrington J.C., Balazs E., Jonard G., Richards K., Morris T.J.
    Nucleic Acids Res. 13:6663-6677(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS).

Entry informationi

Entry nameiCAPSD_CARMV
AccessioniPrimary (citable) accession number: P04383
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 1987
Last sequence update: March 20, 1987
Last modified: October 29, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3